Search Results - "Cundall, Meghan"

Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids by Cundall, Meghan, Sun, Yongchang, Miranda, Christina, Trudeau, John B., Barnes, Stephen, Wenzel, Sally E.

“…Matrix metalloproteinase (MMP)-9 levels are increased in bronchoalveolar lavage (BAL) fluid from patients with severe asthma on high doses of glucocorticoids…”
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Interleukin-13-Dependent Expression of Matrix Metalloproteinase-12 Is Required for the Development of Airway Eosinophilia in Mice by Pouladi, Mahmoud A, Robbins, Clinton S, Swirski, Filip K, Cundall, Meghan, McKenzie, Andrew N.J, Jordana, Manel, Shapiro, Steven D, Stampfli, Martin R

“…We investigated the expression and function of matrix metalloproteinase-12 (MMP-12) in a model of allergic airway inflammation. Mice were sensitized mucosally…”
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Granulocyte Macrophage Colony-Stimulating Factor-Driven Respiratory Mucosal Sensitization Induces Th2 Differentiation and Function Independently of Interleukin-4 by Ritz, Stacey A, Cundall, Meghan J, Gajewska, Beata U, Alvarez, David, Gutierrez-Ramos, Jose-Carlos, Coyle, Anthony J, McKenzie, Andrew N. J, Stampfli, Martin R, Jordana, Manel

“…The development of T helper (Th)2 responses is a key step in the pathogenesis of asthma. Interleukin (IL)-4 is thought to be important, although not strictly…”
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Increased TGF-β2 in severe asthma with eosinophilia by Balzar, Silvana, Chu, Hong Wei, Silkoff, Phillip, Cundall, Meghan, Trudeau, John B., Strand, Matthew, Wenzel, Sally

“…Airway eosinophilia and thickened subepithelial basement membrane have previously been reported to increase with increases in TGF-β expression. However, little…”
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Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: Association with asthma severity, neutrophilic inflammation, and wound repair by Wenzel, Sally E., Balzar, Silvana, Cundall, Meghan, Chu, Hong Wei

“…Background: Asthma likely involves an active injury and repair process, including components such as neutrophils and matrix metalloproteinase 9 (MMP-9)…”
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TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts by Wenzel, Sally E, Trudeau, John B, Barnes, Steve, Zhou, XiuXia, Cundall, Meghan, Westcott, Jay Y, McCord, Kelly, Chu, Hong Wei

“…Chronic diseases may involve an "innate" response followed by an adaptive immune response, of a Th1 or Th2 variety. Little is known regarding the interactions…”
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Increased TGF-beta2 in severe asthma with eosinophilia by Balzar, Silvana, Chu, Hong Wei, Silkoff, Phillip, Cundall, Meghan, Trudeau, John B, Strand, Matthew, Wenzel, Sally

“…Airway eosinophilia and thickened subepithelial basement membrane have previously been reported to increase with increases in TGF-beta expression. However,…”
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Increased TGF-[beta]2 in severe asthma with eosinophilia by Balzar, Silvan a, Chu, Hong Wei, Silkoff, Phillip, Cundall, Meghan, Trudeau, John B, Strand, Matthew, Wenzel, Sally

“…Background Airway eosinophilia and thickened subepithelial basement membrane have previously been reported to increase with increases in TGF-β expression…”
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Interleukin-13 augments transforming growth factor-beta1-induced tissue inhibitor of metalloproteinase-1 expression in primary human airway fibroblasts by Zhou, XiuXia, Trudeau, John B, Schoonover, Kathryn J, Lundin, Jessica I, Barnes, Steve M, Cundall, Meghan J, Wenzel, Sally E

“…Tissue inhibitor of metalloproteinase (TIMP)-1 is a potent inhibitor of activated matrix metalloproteinases (MMPs) such as gelatinases and collagenases. TIMP-1…”
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Neutrophil-derived matrix metalloproteinase-9 is increased in severe asthma and poorly inhibited by glucocorticoids: Atopic Dermatitis Intervention to Control the Atopic March by CUNDALL, Meghan, YONGCHANG SUN, MIRANDA, Christina, TRUDEAU, John B, BARNES, Stephen, WENZEL, Sally E

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Temporal-Spatial Analysis of the Immune Response in a Murine Model of Ovalbumin-Induced Airways Inflammation by Gajewska, Beata U, Swirski, Filip K, Alvarez, David, Ritz, Stacey A, Goncharova, Susanna, Cundall, Meghan, Snider, Denis P, Coyle, Anthony J, Gutierrez-Ramos, Jose-Carlos, Stampfli, Martin R, Jordana, Manel

“…The objective of this study was to define phenotypic changes of antigen-presenting cells (APCs) and T cells in a murine model of antigen-induced airways…”
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Expression of GM-CSF in the airway drives Th2 differentiation and effector function in mice exposed to ragweed intranasally by Cates, Elizabeth C, Fattouh, Ramzi, Alvarez, David, Cundall, Meghan J, Goncharova, Susanna, Stampfli, Martin R, Cwiartka, Monika, Coyle, Anthony J, GutierrezRamos, Jose-Carlos, Waserman, Susan, Jordana, Manel

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TGF-{beta} and IL-13 Synergistically Increase Eotaxin-1 Production in Human Airway Fibroblasts by Wenzel, Sally E, Trudeau, John B, Barnes, Steve, Zhou, XiuXia, Cundall, Meghan, Westcott, Jay Y, McCord, Kelly, Chu, Hong Wei

“…Chronic diseases may involve an "innate" response followed by an adaptive immune response, of a Th1 or Th2 variety. Little is known regarding the interactions…”
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