Search Results - "Cummins, Breschine"
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1
Subnetwork inclusion and switching of multilevel Boolean networks preserve parameter graph structure and dynamics
Published in Frontiers in applied mathematics and statistics (09-08-2024)“…This study addresses a problem of correspondence between dynamics of a parameterized system and the structure of interactions within that system. The structure…”
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2
Experimental guidance for discovering genetic networks through hypothesis reduction on time series
Published in PLoS computational biology (01-10-2022)“…Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are controlled by a relatively small "core" network of transcription factors…”
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3
Assessing biological network dynamics: comparing numerical simulations with analytical decomposition of parameter space
Published in NPJ systems biology and applications (03-07-2023)“…Mathematical modeling of the emergent dynamics of gene regulatory networks (GRN) faces a double challenge of (a) dependence of model dynamics on parameters,…”
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Multistability and predominant hybrid phenotypes in a four node mutually repressive network of Th1/Th2/Th17/Treg differentiation
Published in NPJ systems biology and applications (24-10-2024)“…Elucidating the emergent dynamics of cellular differentiation networks is crucial to understanding cell-fate decisions. Toggle switch – a network of mutually…”
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5
Quantifying robustness of the gap gene network
Published in Journal of theoretical biology (07-03-2024)“…Early development of Drosophila melanogaster (fruit fly) facilitated by the gap gene network has been shown to be incredibly robust, and the same patterns…”
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6
Oscillator death in coupled biochemical oscillators
Published in Mathematics of control, signals, and systems (01-12-2023)“…Circadian rhythm, cell division and metabolic oscillations are rhythmic cellular behaviors that must be both robust but also to respond to changes in their…”
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AN IMPROVED STOICHIOMETRIC MODEL OF CHONDROCYTE CENTRAL METABOLISM: FLUX BALANCE ANALYSIS AND INITIAL MECHANOTRANSDUCTION RESULTS
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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661 - AN IMPROVED STOICHIOMETRIC MODEL OF CHONDROCYTE CENTRAL METABOLISM: FLUX BALANCE ANALYSIS AND INITIAL MECHANOTRANSDUCTION RESULTS
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
Journal Article -
9
Leveraging social networks for identification of people with HIV who are virally unsuppressed
Published in AIDS (London) (01-02-2024)“…This study investigates primary peer-referral engagement (PRE) strategies to assess which strategy results in engaging higher numbers of people with HIV (PWH)…”
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10
A yeast cell cycle pulse generator model shows consistency with multiple oscillatory and checkpoint mutant datasets
Published in Mathematical biosciences (01-01-2024)“…Modeling biological systems holds great promise for speeding up the rate of discovery in systems biology by predicting experimental outcomes and suggesting…”
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11
Robustness and reproducibility of simple and complex synthetic logic circuit designs using a DBTL loop
Published in Synthetic biology (Oxford University Press) (2023)“…Abstract Computational tools addressing various components of design–build–test–learn (DBTL) loops for the construction of synthetic genetic networks exist but…”
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12
Highly-automated, high-throughput replication of yeast-based logic circuit design assessments
Published in Synthetic biology (Oxford University Press) (2022)“…Abstract We describe an experimental campaign that replicated the performance assessment of logic gates engineered into cells of Saccharomyces cerevisiae by…”
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13
Generalized Measures of Population Synchrony
Published 22-06-2024“…Synchronized behavior among individuals is a ubiquitous feature of populations. Understanding mechanisms of (de)synchronization demands meaningful,…”
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14
A yeast cell cycle pulse generator model shows consistency with multiple oscillatory and checkpoint mutant datasets
Published 24-02-2023“…The regulatory mechanisms driving progression of the yeast cell cycle appears to be comprised of an interacting network of transcription factors (TFs),…”
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15
Determining the biomechanical response of a filiform hair array: A low Reynolds number fluid-structure model
Published 01-01-2009“…A model system that has been the subject of many anatomical, developmental, functional, and theoretical studies over the last 30 years is the cercal sensory…”
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Dissertation -
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Determining the biomechanical response of a filiform hair array: A low Reynolds number fluid-structure model
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Dissertation