Search Results - "Cummings, Carrie"

Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study by Smith, Jenny L, Ries, Rhonda E, Hylkema, Tiffany, Alonzo, Todd A, Gerbing, Robert B, Santaguida, Marianne T, Eidenschink Brodersen, Lisa, Pardo, Laura, Cummings, Carrie L, Loeb, Keith R, Le, Quy, Imren, Suzan, Leonti, Amanda R, Gamis, Alan S, Aplenc, Richard, Kolb, E Anders, Farrar, Jason E, Triche, Jr, Timothy J, Nguyen, Cu, Meerzaman, Daoud, Loken, Michael R, Oehler, Vivian G, Bolouri, Hamid, Meshinchi, Soheil

“…A cryptic inv(16)(p13.3q24.3) encoding the fusion is associated with poor outcome in infants with acute megakaryocytic leukemia. We aimed to broaden our…”
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Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets by Morris, Valerie A., Cummings, Carrie L., Korb, Brendan, Boaglio, Sean, Oehler, Vivian G.

“…Acute myeloid leukemia (AML) is characterized by increased proliferation and blocked differentiation of hematopoietic progenitors mediated, in part, by altered…”
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The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia by Oehler, Vivian G., Gooley, Ted, Snyder, David S., Johnston, Laura, Lin, Allen, Cummings, Carrie C., Chu, Su, Bhatia, Ravi, Forman, Stephen J., Negrin, Robert S., Appelbaum, Frederick R., Radich, Jerald P.

“…The impact of imatinib mesylate (IM) treatment for chronic myeloid leukemia (CML) on subsequent allogeneic transplantation is uncertain. To better understand…”
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The preferentially expressed antigen in melanoma (PRAME) inhibits myeloid differentiation in normal hematopoietic and leukemic progenitor cells by Oehler, Vivian G., Guthrie, Katherine A., Cummings, Carrie L., Sabo, Kathleen, Wood, Brent L., Gooley, Ted, Yang, Taimei, Epping, Mirjam T., Shou, Yaping, Pogosova-Agadjanyan, Era, Ladne, Paula, Stirewalt, Derek L., Abkowitz, Janis L., Radich, Jerald P.

“…The preferentially expressed antigen in melanoma (PRAME) is expressed in several hematologic malignancies, but either is not expressed or is expressed at only…”
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Discovery of U2AF1 neoantigens in myeloid neoplasms by Biernacki, Melinda Ann, Lok, Jessica, Black, Ralph Graeme, Foster, Kimberly A, Cummings, Carrie, Woodward, Kyle B, Monahan, Tim, Oehler, Vivian G, Stirewalt, Derek L, Wu, David, Rongvaux, Anthony, Deeg, Hans Joachim, Bleakley, Marie

“…BackgroundMyelodysplastic syndromes (MDS) arise from somatic mutations acquired in hematopoietic stem and progenitor cells, causing cytopenias and predisposing…”
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Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation by Heller, Paula G., Glembotsky, Ana C., Gandhi, Manish J., Cummings, Carrie L., Pirola, Carlos J., Marta, Rosana F., Kornblihtt, Laura I., Drachman, Jonathan G., Molinas, Felisa C.

“…Germ-line heterozygous mutations in the hematopoietic transcription factor AML1 (RUNX1) have been identified in patients with familial platelet disorder with…”
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Congenital amegakaryocytic thrombocytopenia in three siblings: molecular analysis of atypical clinical presentation by Gandhi, Manish J., Pendergrass, Thomas W., Cummings, Carrie C., Ihara, Kenji, Blau, C. Anthony, Drachman, Jonathan G.

“…An 11-year-old girl, presenting with fatigue and bruising, was found to be profoundly pancytopenic. Bone marrow exam and clinical evaluation were consistent…”
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FLJ14813 missense mutation: a candidate for autosomal dominant thrombocytopenia on human chromosome 10 by Gandhi, Manish J, Cummings, Carrie L, Drachman, Jonathan G

“…The gene for a novel nonsyndromic autosomal dominant thrombocytopenia has been previously mapped to a region on human chromosome 10p11-12 (THC2, OMIM number…”
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CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia by Biernacki, Melinda A, Foster, Kimberly A, Woodward, Kyle B, Coon, Michael E, Cummings, Carrie, Cunningham, Tanya M, Dossa, Robson G, Brault, Michelle, Stokke, Jamie, Olsen, Tayla M, Gardner, Kelda, Estey, Elihu, Meshinchi, Soheil, Rongvaux, Anthony, Bleakley, Marie

“…Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary for leukemogenesis, persistent…”
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Custom High Throughput Drug Sensitivity Assay Reveals Therapeutic Options for Chronic Myeloid Leukemia Patients Resistant to or Intolerant of Tyrosine Kinase Inhibitors by Oehler, Vivian G., Chien, Sylvia, Dai, Jin, Cummings, Carrie L., Annis, James, Martins, Timothy J, Becker, Pamela S.

“…Introduction. Tyrosine kinase inhibitors (TKIs) have revolutionized chronic phase (CP) chronic myeloid leukemia (CML) care with many patients achieving major…”
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Myeloid/Lymphoid Neoplasm with Eosinophilia and a Novel RUFY1-Pdgfrb Rearrangement by Williams Silva, Karly, Cummings, Carrie L., Rashid, Nahid, Sala-Torra, Olga, Chen, Xueyan, Liu, Yajuan J., Oehler, Vivian G.

“…▪ Myeloid/lymphoid neoplasms associated with eosinophilia (MLN-Eo) and tyrosine kinase fusion genes include rearrangements of PDGFRB with over 30 different…”
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A Shared SF3B1 Neoantigen Is Presented on Primary Malignant Cells and Induced Pluripotent Stem Cell-Derived Hematopoietic Lines by Biernacki, Melinda Ann, Foster, Kimberly A, Clough, Courtnee, Busch, Stephanie, Cummings, Carrie, Oehler, Vivian G., Stirewalt, Derek, Doulatov, Sergei, Bleakley, Marie

“…Myeloid malignancies are susceptible to immunologic destruction but antigen-specific T cell immunotherapies for these diseases are currently limited…”
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Functional miRNA Expression Library Screen Identifies miRNAs That Alter Proliferation and Differentiation in Acute Myeloid Leukemia by Morris, Valerie A., Cummings, Carrie, Meshinchi, Soheil, Oehler, Vivian

“…Acute myeloid leukemia (AML) is characterized by increased self-renewal of leukemia stem/progenitor cells and failure of differentiation to mature myeloid…”
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KDM7A Is Targeted By MiR-155 in Acute Myeloid Leukemia and Impacts Differentiation by Hughes, Maya D., Morris, Valerie A., Cummings, Carrie, Meshinchi, Soheil, Oehler, Vivian G.

“…Acute myeloid leukemia (AML) is a heterogeneous disease that develops secondary to the acquisition of mutations that disrupt cell differentiation,…”
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Krüppel-like Factors KLF4 and KLF2 Regulate microRNA-150 Expression in Myeloid Leukemias by Morris, Valerie A., Cummings, Carrie, Korb, Brendan, Boaglio, Sean M., Oehler, Vivian

“…Background: Acute myeloid leukemia (AML) is characterized by increased self-renewal of leukemia stem/progenitor cells and failure of differentiation to mature…”
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Absolute quantitative detection of ABL tyrosine kinase domain point mutations in chronic myeloid leukemia using a novel nanofluidic platform and mutation-specific PCR by Oehler, V G, Qin, J, Ramakrishnan, R, Facer, G, Ananthnarayan, S, Cummings, C, Deininger, M, Shah, N, McCormick, F, Willis, S, Daridon, A, Unger, M, Radich, J P

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CD52 Expression In Leukemic Stem/Progenitor Cells by Oehler, Vivian G., Walter, Roland B., Cummings, Carrie, Sala-Torra, Olga, Stirewalt, Derek L., Fang, Min, Radich, Jerald P., Wood, Brent

“…Abstract 2743 CD52 is a cell surface glycoprotein of unknown function that is expressed in B and T lymphocytes, macrophages, and monocytes, but is not…”
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Preferentially Expressed Antigen in Melanoma (PRAME) Expression in Normal and CML CD34+ Progenitor Cells Impairs Myeloid Differentiation by Oehler, Vivian, Cummings, Carrie, Sabo, Kathleen, Wood, Brent, Guthrie, Katherine, Gooley, Ted, Pogosova-Agadjanyan, Era, Ladne, Paula, Stirewalt, Derek, Abkowitz, Janis L., Radich, Jerald

“…PRAME, or the Preferentially Expressed Antigen in Melanoma, is an attractive therapeutic target in cancer treatment. It has been described as a…”
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Planit by Cummings, Carrie

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1936: John Lewis by Cummings, Carrie

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