Search Results - "Culp, David J"
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Murine Salivary Amylase Protects Against Streptococcus mutans -Induced Caries
Published in Frontiers in physiology (02-07-2021)“…Saliva protects dental surfaces against cavities (i. e., dental caries), a highly prevalent infectious disease frequently associated with acidogenic …”
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2
Genomewide Identification of Essential Genes and Fitness Determinants of Streptococcus mutans UA159
Published in mSphere (01-01-2018)“…Transposon mutagenesis coupled with next-generation DNA sequencing (Tn-seq) is a powerful tool for discovering regions of the genome that are required for the…”
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3
Cariogenic potential of the Streptococcus mutans Cid/Lrg system: an in vivo animal case study
Published in Microbiology spectrum (30-10-2024)“…In our prior study using a dual-species ( ) competitive mouse caries model to investigate the contribution of LrgAB to fitness, wild-type and Δ mutants…”
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4
Oral epithelial membrane‐associated mucins and transcriptional changes with Sjögren's syndrome
Published in Oral diseases (01-07-2019)“…Objectives To determine expression and localization of membrane‐associated mucins within human keratinized and non‐keratinized oral epithelia, and to explore…”
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5
Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva
Published in The Journal of biological chemistry (30-01-2015)“…Saliva functions in innate immunity of the oral cavity, protecting against demineralization of teeth (i.e. dental caries), a highly prevalent infectious…”
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6
VIP and muscarinic synergistic mucin secretion by salivary mucous cells is mediated by enhanced PKC activity via VIP-induced release of an intracellular Ca2+ pool
Published in Pflügers Archiv (01-03-2020)“…Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via…”
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7
Manganese transport by Streptococcus sanguinis in acidic conditions and its impact on growth in vitro and in vivo
Published in Molecular microbiology (01-02-2022)“…Streptococcus sanguinis is an oral commensal and an etiological agent of infective endocarditis. Previous studies have identified the SsaACB manganese…”
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8
In Vivo Colonization with Candidate Oral Probiotics Attenuates Streptococcus mutans Colonization and Virulence
Published in Applied and environmental microbiology (01-02-2021)“…A collection of 113 Streptococcus strains from supragingival dental plaque of caries-free individuals were recently tested in vitro for direct antagonism of…”
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Journal Article -
9
Testing of candidate probiotics to prevent dental caries induced by Streptococcus mutans in a mouse model
Published in Journal of applied microbiology (01-05-2022)“…Aims We evaluated two species of human oral commensal streptococci in protection against dental caries induced by Streptococcus mutans. Methods and Results…”
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10
Immunohistochemical Assessment of Fractalkine, Inflammatory Cells, and Human Herpesvirus 7 in Human Salivary Glands
Published in The journal of histochemistry and cytochemistry (01-05-2004)“…Human fractalkine (CX3CL1), a 8-chemokine, is implicated in the mediation of multiple cell functions. In addition to serving as a chemotactic factor for…”
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11
Oral colonization by Streptococcus mutans and caries development is reduced upon deletion of carbonic anhydrase VI expression in saliva
Published in Biochimica et biophysica acta (01-12-2011)“…Carbonic anhydrase VI (CA VI), encoded by type A transcripts of the gene Car6, is a secretory product of salivary glands and is found in the enamel pellicle…”
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12
Tissue Distibution of Murine Muc19/Smgc Gene Products
Published in The journal of histochemistry and cytochemistry (01-02-2010)“…The recently identified gene Muc19/Smgc encodes two diverse splice variants, Smgc (submandibular gland protein C) and Muc19 (mucin 19). Muc19 is a member of…”
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13
Expression of Muc19/Smgc Gene Products During Murine Sublingual Gland Development: Cytodifferentiation and Maturation of Salivary Mucous Cells
Published in The journal of histochemistry and cytochemistry (01-04-2009)“…Muc19/Smgc expresses two splice variants, Smgc (submandibular gland protein C) and Muc19 (mucin 19), the latter a major exocrine product of differentiated…”
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14
The sld genetic defect: two intronic CA repeats promote insertion of the subsequent intron and mRNA decay
Published in The Journal of biological chemistry (24-05-2013)“…The autosomal recessive mutation, sld, attenuates mucous cell expression in murine sublingual glands with corresponding effects on mucin 19 (Muc19). We…”
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15
Tissue Distribution of Murine Muc19/Smgc Gene Products
Published in The journal of histochemistry and cytochemistry (01-02-2010)“…The recently identified gene Muc19/Smgc encodes two diverse splice variants, Smgc (submandibular gland protein C) and Muc19 (mucin 19). Muc19 is a member of…”
Get full text
Journal Article -
16
VIP and muscarinic synergistic mucin secretion by salivary mucous cells is mediated by enhanced PKC activity via VIP-induced release of an intracellular Ca 2+ pool
Published in Pflügers Archiv (01-03-2020)“…Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via…”
Get full text
Journal Article -
17
Salivary Mucin 19 Glycoproteins
Published in The Journal of biological chemistry (30-01-2015)“…Saliva functions in innate immunity of the oral cavity, protecting against demineralization of teeth (i.e. dental caries), a highly prevalent infectious…”
Get full text
Journal Article -
18
Establishment and characterization of a telomerase immortalized human gingival epithelial cell line
Published in Journal of periodontal research (01-12-2013)“…Background and Objective Gingival keratinocytes are used in model systems to investigate the interaction between periodontal bacteria and the epithelium in the…”
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Journal Article -
19
A Descriptive Analysis of Rehearsal Techniques of Expert Middle School Band Directors from Kentucky, Mississippi, and Tennessee
Published 01-01-2018“…The purpose of the present study was to identify rehearsal techniques among expert middle school band directors Kentucky, Tennessee, and Mississippi…”
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Dissertation -
20
In Vivo Colonization with Candidate Oral Probiotics Attenuates Colonization and Virulence of Streptococcus mutans
Published in Applied and environmental microbiology (01-03-2021)“…A collection of 113 strains from supragingival dental plaque of caries-free individuals were recently tested for direct antagonism of the dental caries…”
Get full text
Journal Article