Search Results - "Culot, M."

Predicting human neurotoxicity of propylene glycol methyl ether (PGME) by implementing in vitro neurotoxicity results into toxicokinetic modelling by Reale, E., Sandstrom, J., Culot, M., Hechon, J., Wellens, S., Heymans, M., Tschudi-Monnet, F., Vernez, D., Hopf, N.B.

“…Although organic solvents have been associated with CNS toxicity, neurotoxicity testing is rarely a regulatory requirement. We propose a strategy to assess the…”
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Accelerated Caco-2 cell permeability model for drug discovery by Sevin, E., Dehouck, L., Fabulas-da Costa, A., Cecchelli, R., Dehouck, M.P., Lundquist, S., Culot, M.

“…By culturing Caco-2 cells according to a new and optimized protocol, it has been possible to accelerate the cell culture process in such a way that the cells…”
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Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood–brain barrier by Bellwon, P., Culot, M., Wilmes, A., Schmidt, T., Zurich, M.G., Schultz, L., Schmal, O., Gramowski-Voss, A., Weiss, D.G., Jennings, P., Bal-Price, A., Testai, E., Dekant, W.

“…•CyclosporinA (CsA) uptake into brain tissue limited by Pgp at the blood–brain barrier.•In 2 rodent brain models limited CsA uptake likely due to missing…”
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In vitro blood–brain barrier model adapted to repeated-dose toxicological screening by Fabulas-da Costa, A., Aijjou, R., Hachani, J., Landry, C., Cecchelli, R., Culot, M.

“…•An in vitro BBB model is adapted to study the effects of repeated dose treatment.•The effects on BBB permeability of 12 drugs after repeated treatment are…”
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In vitro blood–brain barrier model adapted to repeated dose toxicological screening by da Costa, A., Hachani, J., Landry, C., Cecchelli, R., Culot, M.

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Effect of Organic Farming Practices on Five Orchard Soil Bio-Indicators by Jamar, L, Magein, H, Lateur, M, Aubinet, M, Culot, M

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Environmental aspects in plant protection practices of non-agricultural pesticide users: case study of communes and the ministry of public works and transport (MET) of the Walloon Region (Belgium) by Godeaux, D, Schiffers, B, Culot, M

“…In order to gain a better understanding of non-agricultural pesticide use and to prepare the legislative and technical dossiers required under the Water…”
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Impact of the plant protection practices on the operators' exposure: survey by the communes and ministry of equipment and transport (MET-RW) by Godeaux, D, Schiffers, B, Culot, M

“…In order to gain a better understanding of non-agricultural pesticide use and to prepare the legislative and technical dossiers required under the Water…”
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Exploring in vitro the potential effects of repeated drug treatment on the distribution of other xenobiotics at the human blood-brain barrier (BBB) by Heymans, M., Lontouo, C., Sevin, E., Gosselet, F., Culot, M.

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Factors influencing microbiological and chemical composition of South-Belgian raw sludge by Guillemet, Thibault A, Maesen, Philippe, Delcarte, Émile, Lognay, Georges C, Gillet, Adeline, Claustriaux, Jean-Jacques, Culot, Marc

“…Wastewater treatment plants produce sludges which are likely to contain microbial pathogens, metallic trace elements and organic micropollutants. The aim of…”
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An in vitro harmonized strategy to assess the toxicity of chemicals using multiple human induced pluripotent stem cell (hiPSC)-derived models by Nunes, C., Singh, P., Mazidi, Z., Murphy, C., Bourguignon, A., Wellens, S, Ghosh, S., Zana, M., Verfaillie, C., Culot, M., Dinnyés, A, Jennings, P., Grillari, J., Exner, T., Zurich, M.-G.

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Biofilters to treat the pesticides wastes from spraying applications: results after 4 years of study by Pigeon, O, De Vleeschouwer, C, Cors, F, Weickmans, B, Huyghebaert, B, Planchon, V, Pussemier, L, Culot, M

“…Biofilters were developed in order to eliminate or reduce the quantity of pesticides from rinsing and cleaning waters of sprayers. Biofilters consist in 1, 2…”
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Development of biofilters to treat the pesticides wastes from spraying applications by Pigeon, O, de Vleeschouwer, C, Cors, F, Weickmans, B, de Ryckel, B, Pussemier, L, Debongnie, Ph, Culot, M

“…Several studies carried out in Europe showed the importance of direct losses to the contamination of surface water by pesticides. These pesticides losses can…”
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Household solid waste generation and characteristics in Cape Haitian city, Republic of Haiti by Philippe, Féniel, Culot, Marc

“…Because of a lack of planning and of the poor HSW (household solid waste) management, the municipal authorities of Cape Haitian are unable to cope with the…”
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An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening by Culot, Maxime, Lundquist, Stefan, Vanuxeem, Dorothée, Nion, Stéphane, Landry, Christophe, Delplace, Yannick, Dehouck, Marie-Pierre, Berezowski, Vincent, Fenart, Laurence, Cecchelli, Roméo

“…There is a growing interest to use in vitro BBB cell assays in early safety assessment of compounds. By modifying a well-validated co-culture model of brain…”
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Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: An in vitro study by Culot, Maxime, Mysiorek, Caroline, Renftel, Mila, Roussel, Benoit D, Hommet, Yannick, Vivien, Denis, Cecchelli, Roméo, Fenart, Laurence, Berezowski, Vincent, Dehouck, Marie-Pierre, Lundquist, Stefan

“…Abstract NXY-059, a polar compound with limited transport across the blood-brain barrier, has demonstrated neuroprotection in several animal models of acute…”
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Ca super(2) super(+) regulation of connexin 43 hemichannels in C6 glioma and glial cells by De Vuyst, E, Wang, N, Decrock, E, De Bock, M, Vinken, M, Van Moorhem, M, Lai, C, Culot, M, Rogiers, V, Cecchelli, R, Naus, C C, Evans, W H, Leybaert, L

“…Connexin hemichannels have a low open probability under normal conditions but open in response to various stimuli, forming a release pathway for small…”
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Database "SIGMA Pro" information system and bibliographical management of active substances of plant protection products and biocides by Rung, J, Tricot, B, Copin, A, Culot, M

“…In order to satisfy its obligations as stipulated in European legislative, in 1998, the Management of Surface Waters in the Walloon Region modified its…”
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Theoretical conformational analysis and synthesis of analogues of the heptapeptide antibiotic K-582 A by De Coen, J L, Wathelet, B, Demeuse, F, Mayon, C, Culot, M, Brakel, J

“…A detailed theoretical conformational analysis of the linear heptapeptide antibiotic [Arg2]K-582 A (Arg-Arg-D-Orn-Thr-D-Orn-Lys-D-Tyr) was carried out. The…”
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Caractérisation physique, chimique et microbiologique de trois sols acides tropicaux du Rwanda sous jachères naturelles et contraintes à leur productivité by Culot M, Bucagu C., Mbonigaba Muhinda JJ, Nzeyimana I.

“…Physical, chemical and microbiological characterization of three tropical acidic soils of Rwanda under natural fallows and productivity constraints. Three…”
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