Search Results - "Cullum, Emily"
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Deficiency in non-classical major histocompatibility class II-like molecule, H2-O confers protection against Staphylococcus aureus in mice
Published in PLoS pathogens (01-06-2024)“…Staphylococcus aureus is a human-adapted pathogen that replicates by asymptomatically colonizing its host. S. aureus is also the causative agent of purulent…”
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Journal Article -
2
G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence
Published in Nucleic acids research (18-09-2015)“…G-quadruplexes (GQs) are alternative DNA secondary structures that can form throughout the human genome and control the replication and transcription of…”
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Journal Article -
3
Validation of a clinical test of auditory emotion recognition
Published in The Journal of the Acoustical Society of America (01-03-2023)“…Currently, there are no accessible clinical tests that can be used to measure auditory emotion recognition. Experimental emotion recognition tasks usually…”
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Journal Article -
4
The Role of H2-O and Additional Novel Loci in Antigen Presentation and the Immune Response against Bacteria and Viruses in Mice
Published 01-01-2022“…Whether or not a host organism mounts a protective immune response to invading pathogens is determined by a number of factors, including the genetic makeup of…”
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Dissertation -
5
H2-O does not preempt autoimmunity but controls murine γherpesvirus MHV68
Published in The Journal of immunology (1950) (22-11-2021)“…H2-O (human HLA-DO) is a relatively conserved non-classical Major Histocompatibility Class II (MHCII)-like molecule. H2-O interaction with H2-M (human HLA-DM)…”
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Journal Article -
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MHC Class II Presentation Is Affected by Polymorphism in the H2-Ob Gene and Additional Loci
Published in The Journal of immunology (1950) (01-07-2021)“…Pathogen-derived peptides are loaded on MHC class II (MHCII) and presented to CD4 T cells for their activation. Peptide loading of MHCII occurs in specialized…”
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Journal Article -
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Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68
Published in The Journal of immunology (1950) (15-12-2021)“…H2-O (human HLA-DO) is a relatively conserved nonclassical MHC class II (MHCII)-like molecule. H2-O interaction with human HLA-DM edits the repertoire of…”
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Journal Article -
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Genetic Control of Neonatal Immune Tolerance to an Exogenous Retrovirus
Published in Journal of virology (23-11-2020)“…Viruses, including retroviruses, can be passed from mothers to their progeny during birth and breastfeeding. It is assumed that newborns may develop immune…”
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Journal Article