Search Results - "Cullen, Matthew D"

Observation of Direct Sulfenium and Selenenium Group Transfer from Thiiranium and Seleniranium Ions to Alkenes by Denmark, Scott E, Collins, William R, Cullen, Matthew D

“…Sulfenium and selenenium ions undergo a stereospecific transfer from the corresponding three-membered ring species (“-iranium ions”) to unactivated alkenes…”
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Successful total hip arthroplasty in a miniature horse by Cullen, Matthew D., Pettitt, Rob A., Tomlinson, Andrew W., Louro, Luis F., Bennell, Alison J., Michael, Robert, Stack, John D.

“…Abstract Objective To describe the surgical treatment, postoperative management, and outcome of a miniature horse undergoing total hip arthroplasty (THA)…”
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Assessment of intrasynovial injection in horses by contrast‐enhanced ultrasonography using air bubbles created by agitation of solution by Ogden, Nadine K. E., Cullen, Matthew D., Stack, John D.

“…Background Accuracy of intrasynovial injections can be challenging to assess in a clinical setting in horses. Contrast‐enhanced ultrasonography (CEUS) using…”
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Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators and Correctors by Giuliano, Kenneth A, Wachi, Shinichiro, Drew, Lawrence, Dukovski, Danijela, Green, Olivia, Bastos, Cecilia, Cullen, Matthew D, Hauck, Sheila, Tait, Bradley D, Munoz, Benito, Lee, Po-Shun, Miller, John Preston

“…Cystic fibrosis (CF) is a lethal genetic disorder caused by mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Despite recent…”
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A Homogeneous Cell-Based Halide-Sensitive Yellow Fluorescence Protein Assay to Identify Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Ion Channel by Smith, Emery, Giuliano, Kenneth A, Shumate, Justin, Baillargeon, Pierre, McEwan, Brigid, Cullen, Matthew D, Miller, John P, Drew, Lawrence, Scampavia, Louis, Spicer, Timothy P

“…Cystic fibrosis (CF), an inherited genetic disease, is caused by mutation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, which encodes…”
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Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings by Deng, Bo-Liang, Cullen, Matthew D., Zhou, Zhigang, Hartman, Tracy L., Buckheit, Robert W., Pannecouque, Christophe, Clercq, Erik De, Fanwick, Phillip E., Cushman, Mark

“…The syntheses and antiviral activities for a new set of alkenyldiarylmethane (ADAM) HIV-1 reverse transcriptase inhibitors bearing benzoxazolone and…”
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Synthesis and Anti-HIV Activity of New Metabolically Stable Alkenyldiarylmethane Non-Nucleoside Reverse Transcriptase Inhibitors Incorporating N-Methoxy Imidoyl Halide and 1,2,4-Oxadiazole Systems by Sakamoto, Takeshi, Cullen, Matthew D, Hartman, Tracy L, Watson, Karen M, Buckheit, Robert W, Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…The alkenyldiarylmethanes (ADAMs) are a unique class of non-nucleoside reverse transcriptase inhibitors (NNRTIs) that are capable of inhibiting HIV-1 reverse…”
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Synthesis and Biological Evaluation of Alkenyldiarylmethane HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors That Possess Increased Hydrolytic Stability by Cullen, Matthew D, Deng, Bo-Liang, Hartman, Tracy L, Watson, Karen M, Buckheit, Robert W, Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…Non-nucleoside inhibitors of HIV reverse transcriptase (NNRTIs), albeit not the mainstays of HIV/AIDS treatment, have become increasingly important in highly…”
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Crystallographic Study of a Novel Subnanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 Reverse Transcriptase by Cullen, Matthew D, Ho, William C, Bauman, Joseph D, Das, Kalyan, Arnold, Eddy, Hartman, Tracy L, Watson, Karen M, Buckheit, Robert W, Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…Two crystal structures have been solved for separate complexes of alkenyldiarylmethane (ADAM) nonnucleoside reverse transcriptase inhibitors (NNRTI) 3 and 4…”
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Inhibition of tubulin polymerization by select alkenyldiarylmethanes by Cullen, Matthew D., Sarkar, Taradas, Hamel, Ernest, Hartman, Tracy L., Watson, Karen M., Buckheit, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…During studies on the alkenyldiarylmethane (ADAM) class of non-nucleoside reverse transcriptase inhibitors (NNRTIs), analogues were discovered that exhibit low…”
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Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors by Cullen, Matthew D., Cheung, York-Fong, Houslay, Miles D., Hartman, Tracy L., Watson, Karen M., Buckheit, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…The alkenyldiarylmethanes (ADAMs) are currently being investigated as non-nucleoside HIV-1 reverse transcriptase inhibitors (NNRTIs) of potential value in the…”
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Crystallographic Study of a Novel Sub-Nanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 (HIV-1) Reverse Transcriptase by Cullen, Matthew D., Ho, William C., Bauman, Joseph D., Das, Kalyan, Arnold, Eddy, Hartman, Tracy L., Watson, Karen M., Buckheit, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

“…Two crystal structures have been solved for separate complexes of alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTI) 3 and 4…”
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Successful total hip arthroplasty in a miniature horse by Cullen, Matthew D, Pettitt, Rob A, Tomlinson, Andrew W, Louro, Luis F, Bennell, Alison J, Michael, Robert, Stack, John D

“…OBJECTIVETo describe the surgical treatment, postoperative management, and outcome of a miniature horse undergoing total hip arthroplasty (THA).STUDY…”
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