Search Results - "Cullen, Lara M."

Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer by Arndt, Greg M, Dossey, Lesley, Cullen, Lara M, Lai, Angela, Druker, Riki, Eisbacher, Michael, Zhang, Chunyan, Tran, Nham, Fan, Hongtao, Retzlaff, Kathy, Bittner, Anton, Raponi, Mitch

“…MicroRNAs (MiRNAs) are short non-coding RNAs that control protein expression through various mechanisms. Their altered expression has been shown to be…”
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Genome-wide screening for gene function using RNAi in mammalian cells by Cullen, Lara M, Arndt, Greg M

“…Mammalian genome sequencing has identified numerous genes requiring functional annotation. The discovery that dsRNA can direct gene‐specific silencing in both…”
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Haemochromatosis and HLA-H by Jazwinska, Elizabeth C, Cullen, Lara M, Busfield, Frances, Pyper, Wendy R, Webb, Sonja I, Powell, Lawrie W, Morris, C. Philip, Walsh, Terence P

“…The recently identified candidate gene, HLA-H, for haemochromatosis (HH) by Feder et al. generated considerable scientific interest coupled with a degree of…”
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Sequence variation in the ATP‐binding domain of the Wilson disease transporter, ATP7B, affects copper transport in a yeast model system by Hsi, Gloria, Cullen, Lara M., Macintyre, Georgina, Chen, Matthew M., Glerum, D. Moira, Cox, Diane W.

“…ATP7B is a copper transporting P‐type ATPase defective in the autosomal recessive copper storage disorder, Wilson disease (WND). Functional assessment of…”
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Functional assessment of the carboxy-terminus of the Wilson disease copper-transporting ATPase, ATP7B by Hsi, Gloria, Cullen, Lara M, Moira Glerum, D, Cox, Diane W

“…The carboxy-terminus of ATP7B, the protein defective in the copper-transport disorder Wilson disease, was investigated with respect to its role in copper…”
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Generation of a transcription map distal to HLA-F by Goldwurm, S, Van der Griend, B F, Banyer, J L, Cullen, L M, Zournazi, A, Menzies, M L, Busfield, F, Little, P F, Jazwinska, E C

“…We have constructed a transcription map covering a 2 Mb region beginning approximately 1 Mb distal to HLA-F. Cosmids isolated from a chromsome 6 library were…”
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Expression of HLA-linked hemochromatosis in subjects homozygous or heterozygous for the C282Y mutation by Crawford, Darrell H.G., Jazwinska, Elizabeth C., Cullen, Lara M., Powell, Lawrie W.

“…Background & Aims: In the absence of a genetic test, diagnostic criteria for hereditary hemochromatosis have been imprecise. The identification of the HFE gene…”
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The Hemochromatosis 845 G→A and 187 C→G Mutations: Prevalence in Non-Caucasian Populations by Cullen, Lara M., Gao, Xiaojiang, Easteal, Simon, Jazwinska, Elizabeth C.

“…Hemochromatosis, the inherited disorder of iron metabolism, leads, if untreated, to progressive iron overload and premature death. The hemochromatosis gene,…”
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Neonatal Screening for the Hemochromatosis Defect by Cullen, Lara M., Summerville, Lesa, Glassick, Tina V., Crawford, Darrell H.G., Powell, Lawrie W., Jazwinska, Elizabeth C.

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Localization, expression and genomic structure of the gene encoding the human serine protease testisin by Hooper, John D., Bowen, Natalie, Marshall, Heidi, Cullen, Lara M., Sood, Raman, Daniels, Rachael, Stuttgen, Melanie A., Normyle, John F., Higgs, Douglas R., Kastner, Daniel L., Ogbourne, Steven M., Pera, Martin F., Jazwinska, Elizabeth C., Antalis, Toni M.

“…Testisin is a recently identified human serine protease expressed by premeiotic testicular germ cells and is a candidate tumor suppressor for testicular…”
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