Search Results - "Cullen, Carlie L."

How Does Transcranial Magnetic Stimulation Influence Glial Cells in the Central Nervous System? by Cullen, Carlie L, Young, Kaylene M

“…Transcranial magnetic stimulation (TMS) is widely used in the clinic, and while it has a direct effect on neuronal excitability, the beneficial effects…”
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Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System by Auderset, Loic, Cullen, Carlie L, Young, Kaylene M

“…The low density lipoprotein-receptor related protein 1 (LRP1) is a large endocytic cell surface receptor that is known to interact with a variety of ligands,…”
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How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood? by Pepper, Renee E, Pitman, Kimberley A, Cullen, Carlie L, Young, Kaylene M

“…Oligodendrocyte progenitor cells (OPCs) are immature cells in the central nervous system (CNS) that can rapidly respond to changes within their environment by…”
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Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function by Cullen, Carlie L., O'Rourke, Megan, Beasley, Shannon J., Auderset, Loic, Zhen, Yilan, Pepper, Renee E., Gasperini, Robert, Young, Kaylene M.

“…Primary cilia are small microtubule‐based organelles capable of transducing signals from growth factor receptors embedded in the cilia membrane…”
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Low dose prenatal ethanol exposure induces anxiety-like behaviour and alters dendritic morphology in the basolateral amygdala of rat offspring by Cullen, Carlie L, Burne, Thomas H J, Lavidis, Nickolas A, Moritz, Karen M

“…Prenatal exposure to high levels of alcohol is strongly associated with poor cognitive outcomes particularly in relation to learning and memory. It is also…”
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Safety of low-intensity repetitive transcranial magneTic brAin stimUlation foR people living with mUltiple Sclerosis (TAURUS): study protocol for a randomised controlled trial by Makowiecki, Kalina, Stevens, Natasha, Cullen, Carlie L, Zarghami, Amin, Nguyen, Phuong Tram, Johnson, Lewis, Rodger, Jennifer, Hinder, Mark R, Barnett, Michael, Young, Kaylene M, Taylor, Bruce V

“…Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease, characterised by oligodendrocyte death and demyelination. Oligodendrocyte progenitor…”
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A phase II trial examining the safety and preliminary efficacy of repetitive transcranial magnetic stimulation (rTMS) for people living with multiple sclerosis by Stevens, Natasha, Ezegbe, Chigozie, Fuh-Ngwa, Valery, Makowiecki, Kalina, Zarghami, Amin, Nguyen, Phuong Tram, Sansom, Julie, Smith, Kate, Laslett, Laura L, Denham, Meg, Cullen, Carlie L, Barnett, Michael H, Hinder, Mark R, Breslin, Monique, Young, Kaylene M, Taylor, Bruce V

“…Multiple sclerosis (MS) is a chronic neurological condition and the leading cause of non-traumatic disability in young adults. MS pathogenesis leads to the…”
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Evaluating Tissue-Specific Recombination in a Pdgfrα-CreERT2 Transgenic Mouse Line by O'Rourke, Megan, Cullen, Carlie L, Auderset, Loic, Pitman, Kimberley A, Achatz, Daniela, Gasperini, Robert, Young, Kaylene M

“…In the central nervous system (CNS) platelet derived growth factor receptor alpha (PDGFRα) is expressed exclusively by oligodendrocyte progenitor cells (OPCs),…”
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Low dose prenatal alcohol exposure does not impair spatial learning and memory in two tests in adult and aged rats by Cullen, Carlie L, Burne, Thomas H J, Lavidis, Nickolas A, Moritz, Karen M

“…Consumption of alcohol during pregnancy can have detrimental impacts on the developing hippocampus, which can lead to deficits in learning and memory function…”
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Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain by Auderset, Loic, Pitman, Kimberley A., Cullen, Carlie L., Pepper, Renee E., Taylor, Bruce V., Foa, Lisa, Young, Kaylene M.

“…Low-density lipoprotein receptor-related protein 1 (LRP1) is a large, endocytic cell surface receptor that is highly expressed by oligodendrocyte progenitor…”
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Protocadherin 15 suppresses oligodendrocyte progenitor cell proliferation and promotes motility through distinct signalling pathways by Zhen, Yilan, Cullen, Carlie L., Ricci, Raphael, Summers, Benjamin S., Rehman, Sakina, Ahmed, Zubair M., Foster, Antoinette Y., Emery, Ben, Gasperini, Robert, Young, Kaylene M.

“…Oligodendrocyte progenitor cells (OPCs) express protocadherin 15 (Pcdh15), a member of the cadherin superfamily of transmembrane proteins. Little is known…”
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Can Thyroid Hormone Analogues Be Used to Overcome Hypomyelination and Demyelination of the Central Nervous System? by Cullen, Carlie L., Young, Kaylene M.

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Oligodendrogenesis and myelination regulate cortical development, plasticity and circuit function by Fletcher, Jessica L., Makowiecki, Kalina, Cullen, Carlie L., Young, Kaylene M.

“…During cortical development and throughout adulthood, oligodendrocytes add myelin internodes to glutamatergic projection neurons and GABAergic inhibitory…”
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Low‐intensity transcranial magnetic stimulation promotes the survival and maturation of newborn oligodendrocytes in the adult mouse brain by Cullen, Carlie L., Senesi, Matteo, Tang, Alexander D., Clutterbuck, Mackenzie T., Auderset, Loic, O'Rourke, Megan E., Rodger, Jennifer, Young, Kaylene M.

“…Neuronal activity is a potent extrinsic regulator of oligodendrocyte generation and central nervous system myelination. Clinically, repetitive transcranial…”
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Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain by Cullen, Carlie L., Pepper, Renee E., Clutterbuck, Mackenzie T., Pitman, Kimberley A., Oorschot, Viola, Auderset, Loic, Tang, Alexander D., Ramm, Georg, Emery, Ben, Rodger, Jennifer, Jolivet, Renaud B., Young, Kaylene M.

“…Central nervous system myelination increases action potential conduction velocity. However, it is unclear how myelination is coordinated to ensure the…”
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Oligodendrogenesis increases in hippocampal grey and white matter prior to locomotor or memory impairment in an adult mouse model of tauopathy by Ferreira, Solène, Pitman, Kimberley A., Summers, Benjamin S., Wang, Shiwei, Young, Kaylene M., Cullen, Carlie L.

“…Myelin and axon losses are associated with cognitive decline in healthy ageing but are worse in people diagnosed with tauopathy. To determine whether tauopathy…”
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Low intensity repetitive transcranial magnetic stimulation enhances remyelination by newborn and surviving oligodendrocytes in the cuprizone model of toxic demyelination by Nguyen, Phuong Tram, Makowiecki, Kalina, Lewis, Thomas S., Fortune, Alastair J., Clutterbuck, Mackenzie, Reale, Laura A., Taylor, Bruce V., Rodger, Jennifer, Cullen, Carlie L., Young, Kaylene M.

“…In people with multiple sclerosis (MS), newborn and surviving oligodendrocytes (OLs) can contribute to remyelination, however, current therapies are unable to…”
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Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain by Ferreira, Solène, Pitman, Kimberley A., Wang, Shiwei, Summers, Benjamin S., Bye, Nicole, Young, Kaylene M., Cullen, Carlie L.

“…In Alzheimer's disease, amyloid plaque formation is associated with the focal death of oligodendrocytes and soluble amyloid β impairs the survival of…”
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Pericyte ablation causes hypoactivity and reactive gliosis in adult mice by Cashion, Jake M., Brown, Lachlan S., Morris, Gary P., Fortune, Alastair J., Courtney, Jo-Maree, Makowiecki, Kalina, Premilovac, Dino, Cullen, Carlie L., Young, Kaylene M., Sutherland, Brad A.

“…•PDGFRβ-CreERT2 mice enable Cre-mediated recombination specifically in pericytes.•Pericyte ablation can be titrated based on tamoxifen dose.•Pericyte ablation…”
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Amyloid β precursor protein regulates neuron survival and maturation in the adult mouse brain by Wang, Shiwei, Bolós, Marta, Clark, Rosemary, Cullen, Carlie L, Southam, Katherine A, Foa, Lisa, Dickson, Tracey C, Young, Kaylene M

“…The amyloid-β precursor protein (APP) is a transmembrane protein that is widely expressed within the central nervous system (CNS). While the pathogenic…”
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