Search Results - "Culberson, Erica J"

Monogenic TCRβ Assembly and Expression Are Paramount for Uniform Antigen Receptor Specificity of Individual αβ T Lymphocytes by Culberson, Erica J, Bassing, Craig H

“…The ability of individual T and B cells to display Ag receptors of unique uniform specificity is the molecular basis of adaptive immunity. Most αβ T cells…”
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Poor-Quality Vβ Recombination Signal Sequences and the DNA Damage Response ATM Kinase Collaborate to Establish TCRβ Gene Repertoire and Allelic Exclusion by Wu, Glendon S, Culberson, Erica J, Allyn, Brittney M, Bassing, Craig H

“…The monoallelic expression (allelic exclusion) of diverse lymphocyte Ag receptor genes enables specific immune responses. Allelic exclusion is achieved by…”
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The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein-Signaled Feedback Inhibition of Vβ Recombination by Culberson, Erica J, Shields, Kymberle C, Glynn, Rebecca A, Allyn, Brittney M, Hayer, Katharina E, Bassing, Craig H

“…In jawed vertebrates, adaptive immunity depends on the process of V(D)J recombination creating vast numbers of T and B lymphocytes that each expresses unique…”
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The RAG1 Ubiquitin Ligase Domain Stimulates Recombination of TCRβ and TCRα Genes and Influences Development of αβ T Cell Lineages by Burn, Thomas N, Miot, Charline, Gordon, Scott M, Culberson, Erica J, Diamond, Tamir, Kreiger, Portia A, Hayer, Katharina E, Bhattacharyya, Anamika, Jones, Jessica M, Bassing, Craig H, Behrens, Edward M

“…RAG1/RAG2 (RAG) endonuclease-mediated assembly of diverse lymphocyte Ag receptor genes by V(D)J recombination is critical for the development and immune…”
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The RAG1 Ubiquitin Ligase Domain Stimulates Recombination of TCR β and α Genes and Influences Development of αβ T Cell Lineages by Burn, Thomas N., Miot, Charline, Gordon, Scott M., Culberson, Erica J., Diamond, Tamir, Kreiger, Portia A., Hayer, Katharina E., Bhattacharyya, Anamika, Jones, Jessica M., Bassing, Craig H., Behrens, Edward M.

“…RAG1/RAG2 (RAG) endonuclease-mediated assembly of diverse lymphocyte antigen receptor genes by V(D)J recombination is critical for the development and immune…”
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