Search Results - "Cukierski, Mark"

Carcinogenicity and hormone studies with the tissue-selective estrogen receptor modulator bazadoxifene by Wright, David J., Earnhardt, J. Nicole, Perry, Richard, Bailey, Steven, Komm, Barry, Minck, Daniel R., Cukierski, Mark A.

“…Bazedoxifene Acetate (BZA) is a selective estrogen receptor modulator (SERM) that is approved for the prevention and/or treatment of osteoporosis in…”
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Carcinogenicity and Hormone Studies with the Tissue-Selective Estrogen Receptor Modulator Bazedoxifene by Wright, David J., Earnhardt, J. Nicole, Perry, Richard, Bailey, Steven, Komm, Barry, Minck, Daniel R., Cukierski, Mark A.

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Renal Tumors in Male Rats Following Long-term Administration of Bazedoxifene, a Tissue-selective Estrogen Receptor Modulator by Perry, Rick, Thompson, Carol A., Earnhardt, J. Nicole, Wright, David J., Bailey, Steven, Komm, Barry, Cukierski, Mark A.

“…Bazedoxifene acetate (BZA) is a selective estrogen receptor modulator that is approved in a number of countries for the prevention and/or treatment of…”
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The role of maternal toxicity in lovastatin-induced developmental toxicity by Lankas, George R., Cukierski, Mark A., Wise, L. David

“…The role of maternal toxicity in lovastatin‐induced developmental toxicity in rats was examined in a series of studies. The first study administered lovastatin…”
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Impairment of male fertility induced by muscarinic receptor antagonists in rats by Ban, Yoshiki, Sato, Takahiro, Nakatsuka, Toshio, Kemi, Masayuki, Samura, Keiji, Matsumoto, Hiroyoshi, Cukierski, Mark A, van Zwieten, Matthew J

“…Male rats were treated with a muscarinic receptor antagonist at 3, 10, and 100 mg/kg/day for 4 weeks prior to mating with untreated females and their…”
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Carcinogenicity and Hormone Studies with the Tissue-Selective Estrogen Receptor Modulator Bazedoxifene: Erratum by Wright, David J., Earnhardt, J. Nicole, Perry, Richard, Bailey, Steven, Komm, Barry, Minck, Daniel R., Cukierski, Mark A.

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Development of the brain in staged embryos of the long-tailed monkey (Macaca fascicularis) by Makori, Norbert, Rodriguez, Cruz G., Cukierski, Mark A., Hendrickx, Andrew G.

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Abstract 1677: Epithelial hyperplasia induced by a selective B-Raf inhibitor, WYE-130600 by Besteman, Elizabeth, Bienvenu, Jean-Guy, Chaudhary, Inder, Cukierski, Mark, Marsh, Billie, Surprenant, Beth

“…Abstract The Raf-MEK-ERK signaling pathway is critical for cell survival, growth, proliferation and tumorigenesis. The RAF kinases, ARAF, BRAF and CRAF, are…”
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Assessment of male reproductive toxicity in rats under ICH guidelines by Cukierski, M A

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Assessment of immunization against recombinant human bone morphogenetic protein-2 (dibotermin alpha) on reproduction and development in rabbits by Wright, David J., Minck, Daniel R., Nowak, John, Warner, Garvin, Cukierski, Mark

“…BACKGROUND: To determine if the fetus was affected by maternal antibodies to BMP‐2, the antibody response and developmental effects in fetuses from does…”
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Development of the upper lip by Senders, Craig W, Peterson, Erik C, Hendrickx, Andrew G, Cukierski, Mark A

“…To affirm and reanalyze George L. Streeter's "merging theory" of upper-lip development in primates by observing progressive embryologic stages in facial…”
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Teratogenic effects of the endothelin receptor antagonist L-753,037 in the rat by Spence, Stan, Anderson, Charles, Cukierski, Mark, Patrick, Darryl

“…The studies presented in this paper were undertaken to investigate the effects of L-753,037, a balanced endothelin receptor antagonist with similar affinity…”
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Effects of porcine growth hormone on pregnancy and fetal/neonatal development in the rat by Spence, S, Mattson, B, Vetter, C, Cukierski, M, Prahalada, S

“…Porcine growth hormone was given subcutaneously twice daily to two groups of 20 females at dose levels of 0.5 and 2.5 IU/kg (1 and 5 IU/kg/day). A control…”
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Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5 alpha-reductase inhibitor by Wise, L D, Minsker, D H, Cukierski, M A, Clark, R L, Prahalada, S, Antonello, J M, MacDonald, J S, Robertson, R T

“…Finasteride, a 5 alpha-reductase inhibitor, was investigated for its effects on fertility in male rats as part of its preclinical safety assessment. Studies…”
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Neodymium:yttrium-aluminum-garnet laser occlusion of rhesus placental vasculature via fetoscopy by DeLia, J E, Cukierski, M A, Lundergan, D K, Kochenour, N K

“…We tested the feasibility of photocoagulating placental vascular communications with a fetoscopically delivered neodymium:yttrium-aluminum-garnet laser in 12…”
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Predicting the human teratogenic potential of the anticonvulsant, valproic acid, from a non-human primate model by Mast, T J, Cukierski, M A, Nau, H, Hendrickx, A G

“…The anticonvulsant, valproic acid (VPA) is a suspected human teratogen. This study, employing the rhesus monkey as an animal model, demonstrates that VPA has a…”
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Tubuloreticular inclusions in placental chorionic villi of rhesus monkeys after maternal treatment with interferon by Feldman, D, Hoar, R M, Niemann, W H, Valentine, T, Cukierski, M, Hendrickx, A G

“…Tubuloreticular inclusions were observed in placental chorionic villi of rhesus monkeys after pregnant female monkeys were injected intramuscularly with…”
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Synthesis and transport studies of the intrasyncytial lamina: an unusual placental basement membrane in the little brown bat, Myotis lucifugus by Cukierski, M A

“…The chorioallantoic placenta of Myotis lucifugus undergoes a transition from endotheliochorial to hemochorial. The original maternal endothelial basement…”
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Report 3 : ASSESSMENT OF MALE REPRODUCTIVE TOXICITY IN RATS UNDER ICH GUIDELINES (<Session 2>Reproductive toxicities) by Mark A. Ph. D. CUKIERSKI

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