Search Results - "Cuker, A"

Contemporary management of primary immune thrombocytopenia in adults by LAKSHMANAN, S., CUKER, A.

“…Immune thrombocytopenia (ITP) comprises a syndrome of diverse disorders that have in common immune‐mediated thrombocytopenia, but that differ with respect to…”
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The HIT Expert Probability (HEP) Score: a novel pre‐test probability model for heparin‐induced thrombocytopenia based on broad expert opinion by CUKER, A., AREPALLY, G., CROWTHER, M. A., RICE, L., DATKO, F., HOOK, K., PROPERT, K. J., KUTER, D. J., ORTEL, T. L., KONKLE, B. A., CINES, D. B.

“…Background: The diagnosis of heparin‐induced thrombocytopenia (HIT) is challenging. Over‐diagnosis and over‐treatment are common. Objectives: To develop a…”
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Recombinant porcine sequence factor VIII (rpFVIII) for acquired haemophilia A: practical clinical experience of its use in seven patients by Tarantino, M. D., Cuker, A., Hardesty, B., Roberts, J. C., Sholzberg, M.

“…Introduction A recombinant porcine factor VIII B‐domain‐deleted product (rpFVIII; OBIZUR, Baxalta Incorporated, Deerfield, IL 60015, USA) was recently approved…”
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Laboratory measurement of the direct oral anticoagulants: Indications and impact on management in clinical practice by Wright, C., Brown, R., Cuker, A.

“…Although the direct oral anticoagulants (DOACs) do not require routine laboratory monitoring, there may be special situations in which measurement of drug…”
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Inappropriate documentation of heparin allergy in the medical record because of misdiagnosis of heparin‐induced thrombocytopenia: frequency and consequences by McMahon, C. M., Tanhehco, Y. C., Cuker, A.

“…Essentials Misdiagnosis of heparin‐induced thrombocytopenia (HIT) may be associated with adverse outcomes. We conducted a study of patients with a heparin…”
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Diagnostic accuracy of IgG‐specific versus polyspecific enzyme‐linked immunoassays in heparin‐induced thrombocytopenia: a systematic review and meta‐analysis by Husseinzadeh, H. D., Gimotty, P. A., Pishko, A. M., Buckley, M., Warkentin, T. E., Cuker, A.

“…Essentials Immunoassay specificity varies in heparin‐induced thrombocytopenia (HIT) testing. This meta‐analysis examined 9 studies that tested samples by both…”
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Evaluation of the utility of the ISTH-BAT in haemophilia carriers: a multinational study by James, P. D., Mahlangu, J., Bidlingmaier, C., Mingot-Castellano, M. E., Chitlur, M., Fogarty, P. F., Cuker, A., Mancuso, M. E., Holme, P. A., Grabell, J., Satkunam, N., Hopman, W. M., Mathew, P.

“…Introduction There has been increasing recognition in recent years that female carriers of haemophilia manifest abnormal bleeding; however, data on the use of…”
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Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program by Christopherson, Pamela A., Haberichter, Sandra L., Flood, Veronica H., Perry, Crystal L., Sadler, Brooke E., Bellissimo, Daniel B., Di Paola, Jorge, Montgomery, Robert R., Abshire, T, Weiler, H, Lillicrap, D, James, P, O’Donnell, J, Ng, C, Bennett, C, Sidonio, R, Manco‐Johnson, M, Journeycake, J, Zia, A, Lusher, J, Rajpurkar, M, Shapiro, A, Lentz, S, Gill, J, Leissinger, C, Ragni, M, Tarantino, M, Roberts, J, Hord, J, Strouse, J, Ma, A, Valentino, L, Boggio, L, Sharathkumar, A, Gruppo, R, Kerlin, B, Kulkarni, R, Green, D, Hoots, K, Brown, D, Mahoney, D, Mathias, L, Bedros, A, Diamond, C, Neff, A, DiMichele, D, Giardina, P, Cohen, A, Paidas, M, Werner, E, Matsunaga, A, Shafer, F, Konkle, B, Cuker, A, Kouides, P, Stein, D

“…Background Type 3 von Willebrand Disease (VWD) is a rare and severe form of VWD characterized by the absence of von Willebrand factor (VWF). Objectives As part…”
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Prevalence of and risk factors for cerebral microbleeds among adult patients with haemophilia A or B by Husseinzadeh, H., Chiasakul, T., Gimotty, P. A., Pukenas, B., Wolf, R., Kelty, M., Chiang, E., Fogarty, P. F., Cuker, A.

“…Introduction Cerebral microbleeds (CMBs) represent clinically silent haemorrhagic events. Cerebral microbleeds (CMBs) portend negative neurovascular and…”
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Prevalence and impact of obesity in people with haemophilia: Review of literature and expert discussion around implementing weight management guidelines by Kahan, S., Cuker, A., Kushner, R. F., Maahs, J., Recht, M., Wadden, T., Willis, T., Majumdar, S., Ungar, D., Cooper, D.

“…Obesity affects more than 35% of Americans, increasing the risk of more than 200 comorbid conditions, impaired quality of life and premature mortality. This…”
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Recombinant factor VIIa addition to haemophilic blood perfused over collagen/tissue factor can sufficiently bypass the factor IXa/VIIIa defect to rescue fibrin generation by Li, R., Panckeri, K. A., Fogarty, P. F., Cuker, A., Diamond, S. L.

“…Introduction Factor VIII (FVIII) or factor IX (FIX)‐deficient haemophilic patients display deficits in platelet and fibrin deposition under flow detectable in…”
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Interlaboratory agreement in the monitoring of unfractionated heparin using the anti‐factor Xa‐correlated activated partial thromboplastin time by CUKER, A., PTASHKIN, B., KONKLE, B. A., PIPE, S. W., WHINNA, H. C., ZHENG, X. L., CINES, D. B., POLLAK, E. S.

“…Background: In an effort to improve interlaboratory agreement in the monitoring of unfractionated heparin (UFH), the College of American Pathologists (CAP)…”
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Similarity in joint function limitation in Type 3 von Willebrand's disease and moderate haemophilia A by Sood, S. L., Cuker, A., Wang, C., Metjian, A. D., Chiang, E. Y., Soucie, J. M., Konkle, B. A.

“…Summary Type 3 von Willebrand's disease (VWD) is a rare bleeding diathesis with complete or near complete deficiency of von Willebrand factor (VWF) and low…”
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Heparin-induced thrombocytopenia (HIT) in 2011: an epidemic of overdiagnosis by Cuker, Adam

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Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease by METJIAN, A. D., WANG, C., SOOD, S. L., CUKER, A., PETERSON, S. M., SOUCIE, J. M., KONKLE, B. A.

“…Type 3 von Willebrand disease (VWD) is a rare bleeding disorder with markedly decreased or absent von Willebrand factor (VWF) protein, accompanied by a…”
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Treatment of primary autoimmune thrombocytopenia (AITP) [1] by Schipperus, M. R., Fijnheer, R., Pabinger, I., Godeau, B., Michel, M., Tomiyama, Y., Imbach, P., Cuker, A., Cines, B., Panzer, S., Reesink, H. W.

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Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant by George, Lindsey A, Sullivan, Spencer K, Giermasz, Adam, Rasko, John E.J, Samelson-Jones, Benjamin J, Ducore, Jonathan, Cuker, Adam, Sullivan, Lisa M, Majumdar, Suvankar, Teitel, Jerome, McGuinn, Catherine E, Ragni, Margaret V, Luk, Alvin Y, Hui, Daniel, Wright, J. Fraser, Chen, Yifeng, Liu, Yun, Wachtel, Katie, Winters, Angela, Tiefenbacher, Stefan, Arruda, Valder R, van der Loo, Johannes C.M, Zelenaia, Olga, Takefman, Daniel, Carr, Marcus E, Couto, Linda B, Anguela, Xavier M, High, Katherine A

“…An adeno-associated viral vector was used to introduce a FIX gene with enhanced biologic activity in 10 participants with hemophilia B. The annualized bleeding…”
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How I treat heparin-induced thrombocytopenia by Cuker, Adam, Cines, Douglas B.

“…Heparin-induced thrombocytopenia is a prothrombotic adverse drug effect induced by platelet-activating antibodies against multimolecular complexes of platelet…”
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OC 15.1 A Novel Point-of-Care Whole Blood Portable Analyzer for Direct Oral Anticoagulant Monitoring by Cuker, A., Santiago, M., Tubia, I., Mijangos, I., Montes, T.

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PB0534 Rapid Measurement of DOAC Concentration and Platelet Function Using Whole Blood in a Disposable Microfluidic Device by Rossi, J., Panckeri, K., Ghosh, S., Grosser, T., Cuker, A., Diamond, S.

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