Search Results - "Cuffini Silvia"
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NMR Longitudinal Rotating Frame Relaxation Time (T1ρ) with a Weak Spin Locking Field as an Approach to Characterize Solid-State Active Pharmaceutical Ingredients: Proof of Concept
Published in Analytical chemistry (Washington) (28-05-2024)“…Nuclear magnetic resonance (NMR) longitudinal rotating frame relaxation time (T1ρ), rarely used in low-field NMR, can be more effective than conventional T1…”
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2
Drug Solubility Enhancement through the Preparation of Multicomponent Organic Materials: Eutectics of Lovastatin with Carboxylic Acids
Published in Pharmaceutics (09-03-2019)“…Lovastatin (LOV) is a drug used to treat hypercholesterolemia. Recent studies have identified its antioxidant effects and potential use in the treatment of…”
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3
Eutectic mixtures containing the active pharmaceutical ingredient ezetimibe: Phase diagrams, solid state characterization and dissolution profiles
Published in Journal of crystal growth (15-09-2024)“…•Eutectic systems of Ezetimibe with Methylparaben, Salicylic Acid and Nicotinamide.•Phase and Tamman diagrams and structural analyses of Ezetimibe…”
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4
Quantitative analysis and evaluation of solid-state stability of mebendazole Forms A and C suspensions by powder X-ray diffraction using the Rietveld method
Published in International journal of pharmaceutics (25-01-2024)“…Mebendazole (MBZ) is a broad-spectrum active pharmaceutical ingredient (API) indicated for treating parasitosis, and it has three solid-state forms, A, B, and…”
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5
Eutectic mixtures of nevirapine: Phase diagrams, solid-state characterization, and dissolution studies
Published in Journal of crystal growth (01-01-2025)“…•Phase diagram and structural analyses of the eutectic systems: nevirapine–caffeine and nevirapine–theophylline.•Construction and comparison of the phase…”
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6
Challenging identification of polymorphic mixture: Polymorphs I, II and III in olanzapine raw materials
Published in International journal of pharmaceutics (10-02-2019)“…[Display omitted] Olanzapine (OLZ), a drug for the treatment of schizophrenia, presents in more than 60 crystal forms. Polymorphs I, II and III were reported,…”
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Polymorphism of Anti-HIV Drug Efavirenz: Investigations on Thermodynamic and Dissolution Properties
Published in Crystal growth & design (01-10-2014)“…Polymorphs, cocrystals, solvates, and hydrates have been reported for efavirenz (EFV), which is part of high activity antiretroviral therapy (HAART), and it is…”
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8
New Multicomponent Forms of the Antiretroviral Nevirapine with Improved Dissolution Performance
Published in Crystal growth & design (05-02-2020)“…In the pharmaceutical area, some drugs exhibit physicochemical properties that adversely affect the formulation processes for bioavailability and…”
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9
The effect of solution environment and the electrostatic factor on the crystallisation of desmotropes of irbesartan
Published in RSC advances (11-02-2019)“…The experimental conditions necessary for stabilising irbesartan (IBS) tautomers in solution and selectively obtaining the desmotropic crystal forms are…”
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10
Solid-state evaluation and polymorphic quantification of venlafaxine hydrochloride raw materials using the Rietveld method
Published in Talanta (Oxford) (15-12-2013)“…Venlafaxine hydrochloride (VEN) is an antidepressant drug widely used for the treatment of depression. The purpose of this study was to carry out the…”
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11
Effect of ethylcellulose on the structure and stability of non-aqueous oil based propylene glycol emulsions
Published in Food research international (01-08-2014)“…The hydrophobic polymer ethylcellulose (EC) has been used to structure vegetable oils and as a stabilizer of oil/water (o/w) emulsions, among other non food…”
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12
Development and validation of an intrinsic dissolution method for nimodipine polymorphs
Published in Open Chemistry (01-05-2014)Get full text
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13
Determination of Azithromycin by an Alternative FIA Amperometric Method for Different Pharmaceutical Applications
Published in Industrial & engineering chemistry research (10-04-2013)“…This work presents a fast and reliable electroanalytical procedure for the quantification of azithromycin (AZ) in different systems that couples flow injection…”
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14
Dissolution properties, solid-state transformation and polymorphic crystallization: progesterone case study
Published in Pharmaceutical development and technology (01-11-2014)“…Abstract Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2…”
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15
Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties
Published in Journal of pharmaceutical analysis (01-10-2019)“…Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between…”
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16
Nuclear Quadrupole Resonance: A Technique to Control Hydration Processes in the Pharmaceutical Industry
Published in Analytical chemistry (Washington) (01-03-2011)“…Pharmaceuticals can exist in many solid forms, which can have different physical and chemical properties. These solid forms include polymorphs, solvates,…”
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17
The staling of bread: an X-ray diffraction study
Published in European food research & technology (01-02-2004)“…Bread crumb X-ray patterns were analysed by different methods, the objective being to provide more in-depth knowledge of the relationships among starch…”
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18
Morphology study of progesterone polymorphs prepared by polymer-induced heteronucleation (PIHn)
Published in Scanning (01-07-2013)“…Summary In this article, morphology of progesterone polymorphs prepared by polymer‐induced heteronucleation (PIHn) technique was studied. Hydroxypropyl…”
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DETERMINATION OF DICLOFENAC SODIUM IN RABBIT PLASMA BY HPLC/UV: EVALUATION AND CHARACTERIZATION OF ITS CRYSTALLINE FORMS, ANHYDROUS AND HYDRATE, ON THE ANTIPYRETIC EFFECT
Published in Journal of liquid chromatography & related technologies (01-01-2012)“…Diclofenac sodium (DS) is a non-steroidal anti-inflammatory drug that is widely prescribed for the treatment of rheumatoid arthritis and post-surgery…”
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Solid-state characterization and dissolution properties of Fluvastatin sodium salt hydrates
Published in Pharmaceutical development and technology (01-03-2013)“…The present study reports the solid-state properties of Fluvastatin sodium salt crystallized from different solvents for comparison with crystalline forms of…”
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