Search Results - "Cuffari, C."

Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease by Cuffari, C, Hunt, S, Bayless, T

“…BACKGROUND AND AIM The immunosuppressive properties of 6-mercaptopurine and its parent compound azathioprine are mediated by their intracellular metabolism…”
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Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease by Cuffari, Carmen, Dassopoulos, Themistocles, Turnbough, Lisa, Thompson, Richard E, Bayless, Theodore M

“…Genetic polymorphism in thiopurine methyltransferase (TPMT) activity may influence clinical responsiveness to azathioprine (AZA) therapy. Our aim was to…”
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Critical Analysis of Bariatric Procedures in Prader‐Willi Syndrome by Scheimann, AO, Butler, MG, Gourash, L, Cuffari, C, Klish, W

“…ABSTRACT Prader‐Willi syndrome (PWS) is a complex genetic disorder localized to chromosome 15 and is considered the most common genetic cause of the…”
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Esophageal polyps in pediatric patients undergoing routine diagnostic upper gastrointestinal endoscopy: a multicenter study by Septer, S., Cuffari, C., Attard, T. M.

“…Summary Esophageal polyps are uncommon findings in pediatric patients, and reports have been limited to case reports. Esophageal polyps have been previously…”
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6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity by Cuffari, C, Théorêt, Y, Latour, S, Seidman, G

“…BACKGROUND: 6-Mercaptopurine (6-MP) has confirmed short and longterm efficacy in the treatment of IBD. However, the relation between its metabolism, efficacy,…”
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Gastric polyps in pediatrics: an 18-year hospital-based analysis by Attard, T.M, Yardley, J.H, Cuffari, C

“…OBJECTIVE: Gastric polyps are recognized as either an incidental finding on routine gastroscopy or a frequent occurrence in patients with polyposis syndromes…”
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Enhanced bioavailability of azathioprine compared to 6‐mercaptopurine therapy in inflammatory bowel disease: correlation with treatment efficacy by Cuffari, C., Hunt, S., Bayless, T. M.

“…Background: Azathioprine and 6‐mercaptopurine have proven efficacy in the treatment of Crohn’s disease. Immunosuppression is mediated by their intracellular…”
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Gastric polyps in pediatrics: an 18-year hospital-based analysis by Attard, T M, Yardley, J H, Cuffari, C

“…Gastric polyps are recognized as either an incidental finding on routine gastroscopy or a frequent occurrence in patients with polyposis syndromes. The aim of…”
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Peripheral blood mononuclear cell DNA 6-thioguanine metabolite levels correlate with decreased interferon-gamma production in patients with Crohn's disease on AZA therapy by Cuffari, C, Li, D Y, Mahoney, J, Barnes, Y, Bayless, T M

“…6-Mercaptopurine (6-MP) and its prodrug azathioprine (AZA) are well known for their lymphocytotoxic and bone marrow suppressive effects in the management of…”
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Inflammatory bowel disease in the pediatric and adolescent patient by Cuffari, C, Darbari, A

“…Advances in genetic testing have confirmed the presence of susceptibility loci on chromosomes 12 and 16 for UC and CD. These loci show a strong association…”
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Optimization of the safety and efficacy of interferon beta 1b and azathioprine combination therapy in multiple sclerosis by Pulicken, M, Bash, C N, Costello, K, Said, A, Cuffari, C, Wilterdink, J L, Rogg, J M, Mills, P, Calabresi, P A

“…We conducted an open-label pilot clinical trial to evaluate the safety and efficacy of adding oral azathioprine to the treatment regimen of 15 multiple…”
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Keep meaning in conversational coordination by Cuffari, Elena C

“…Coordination is a widely employed term across recent quantitative and qualitative approaches to intersubjectivity, particularly approaches that give embodiment…”
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Pharmacogenomics of azathioprine (AZA) metabolism in IBD: correlation with treatment efficacy by Cuffari, C., Bayless, T.M.

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Optimizing therapy in patients with pancolitis by Cuffari, Carmen, Present, Daniel H, Bayless, Theodore M, Lichtenstein, Gary R

“…Pancolitis affects approximately 20% to 40% of the total ulcerative colitis population and remains a therapeutic challenge for clinicians. Practitioners must…”
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Pediatric jejunoileitis: A severe Crohn's disease phenotype that requires intensive nutritional management by Attard, T. M., Horton, K. M., DeVito, K., Darbari, A., Oliva‐Hemker, M., Thompson, R., Cuffari, C.

“…Background: Jejunoileitis (JI) is an unusual manifestation of Crohn's disease (CD) that has been associated with high morbidity and the frequent need for…”
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Quantitation of 6-thioguanine in peripheral blood leukocyte DNA in Crohn's disease patients on maintenance 6-mercaptopurine therapy by Cuffari, C, Seidman, E G, Latour, S, Théorêt, Y

“…The effects of 6-mercaptopurine (6MP) in inflammatory bowel disease are believed to be primarily mediated by its metabolite 6-thioguanine (6TG). Our aim was to…”
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The Clinical Spectrum of Duodenal Polyps in Pediatrics by Attard, T M, Abraham, S C, Cuffari, C

“…OBJECTIVESThe aim of this retrospective study was to determine the prevalence, clinical presentation, and histologic subclassification of duodenal polyps…”
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Inflammatory bowel disease in children: a pediatrician's perspective by Cuffari, C

“…Crohn's disease (CD) and ulcerative colitis (UC) are common and heterogeneous chronic inflammatory bowel disorders of childhood that account for up to 25% of…”
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Peripheral Blood Mononuclear Cell DNA 6-Thioguanine Metabolite Levels Correlate with Decreased Interferon-  Production in Patients with Crohn's Disease on AZA Therapy by Cuffari, C., Li, D. Y., Mahoney, J., Barnes, Y., Bayless, T. M.

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Routine use of the nitric oxide stain in the differential diagnosis of Hirschsprung's disease by Cuffari, C, Rubin, S Z, Krantis, A

“…Hirschsprung's disease (HD) is defined as a congenital absence of ganglion cells in the distal bowel. Functionally, there is a loss of enteric neuromuscular…”
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