Search Results - "Cuff, Simone M."

Using artificial intelligence to reduce diagnostic workload without compromising detection of urinary tract infections by Burton, Ross J, Albur, Mahableshwar, Eberl, Matthias, Cuff, Simone M

“…A substantial proportion of microbiological screening in diagnostic laboratories is due to suspected urinary tract infections (UTIs), yet approximately two…”
Get full text

CytoPy: An autonomous cytometry analysis framework by Burton, Ross J, Ahmed, Raya, Cuff, Simone M, Baker, Sarah, Artemiou, Andreas, Eberl, Matthias

“…Cytometry analysis has seen a considerable expansion in recent years in the maximum number of parameters that can be acquired in a single experiment. In…”
Get full text

Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis by Brook, Amy C., Jenkins, Robert H., Clayton, Aled, Kift-Morgan, Ann, Raby, Anne-Catherine, Shephard, Alex P., Mariotti, Barbara, Cuff, Simone M., Bazzoni, Flavia, Bowen, Timothy, Fraser, Donald J., Eberl, Matthias

“…Infection remains a major cause of morbidity, mortality and technique failure in patients with end stage kidney failure who receive peritoneal dialysis (PD)…”
Get full text

CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue by Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A, Snelgrove, Robert J, Lacaze, Paul, Jacques, Laura C, Cuff, Simone M, Stanton, Richard J, Gallimore, Awen M, Hussell, Tracy, Wilkinson, Gavin W G, Ghazal, Peter, Taylor, Philip R, Humphreys, Ian R

“…CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200…”
Get full text

GeoWaVe: geometric median clustering with weighted voting for ensemble clustering of cytometry data by Burton, Ross J, Cuff, Simone M, Morgan, Matt P, Artemiou, Andreas, Eberl, Matthias

“…Abstract Motivation Clustering is an unsupervised method for identifying structure in unlabelled data. In the context of cytometry, it is typically used to…”
Get full text

Conventional and unconventional T-cell responses contribute to the prediction of clinical outcome and causative bacterial pathogen in sepsis patients by Burton, Ross J, Raffray, Loïc, Moet, Linda M, Cuff, Simone M, White, Daniel A, Baker, Sarah E, Moser, Bernhard, O'Donnell, Valerie B, Ghazal, Peter, Morgan, Matt P, Artemiou, Andreas, Eberl, Matthias

“…Sepsis is characterized by a dysfunctional host response to infection culminating in life-threatening organ failure that requires complex patient management…”
Get full text

Control of neutrophil influx during peritonitis by transcriptional cross‐regulation of chemokine CXCL1 by IL‐17 and IFN‐γ by Catar, Rusan A, Chen, Lei, Cuff, Simone M, Kift‐Morgan, Ann, Eberl, Matthias, Kettritz, Ralph, Kamhieh‐Milz, Julian, Moll, Guido, Li, Qing, Zhao, Hongfan, Kawka, Edyta, Zickler, Daniel, Parekh, Gita, Davis, Paul, Fraser, Donald J, Dragun, Duska, Eckardt, Kai‐Uwe, Jörres, Achim, Witowski, Janusz

“…Neutrophil infiltration is a hallmark of peritoneal inflammation, but mechanisms regulating neutrophil recruitment in patients with peritoneal dialysis…”
Get full text

The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T‐cell immunity by Twohig, Jason P., Marsden, Morgan, Cuff, Simone M., Ferdinand, John R., Gallimore, Awen M., Perks, William V., Al‐Shamkhani, Aymen, Humphreys, Ian R., Wang, Eddie C. Y.

“…ABSTRACT Death receptor 3 (DR3, TNFRSF25), the closest family relative to tumor necrosis factor receptor 1, promotes CD4+ T‐cell‐driven inflammatory disease…”
Get full text

Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation by Cuff, Simone M, Merola, Joseph P, Twohig, Jason P, Eberl, Matthias, Gray, William P

“…Abstract Rapid determination of an infective aetiology causing neurological inflammation in the cerebrospinal fluid can be challenging in clinical practice…”
Get full text

The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasis by Twohig, Jason P, Cuff, Simone M, Yong, Audrey A, Wang, Eddie C Y

“…Tumor necrosis factor receptor superfamily (TNFRSF) members were initially identified as immunological mediators, and are still commonly perceived as…”
Get more information

IL-21 conditions antigen-presenting human γδ T-cells to promote IL-10 expression in naïve and memory CD4 + T-cells by Tyler, Christopher J, Hoti, Inva, Griffiths, Daniel D, Cuff, Simone M, Andrews, Robert, Keisker, Maximilian, Ahmed, Raya, Hansen, Hinrich P, Lindsay, James O, Stagg, Andrew J, Moser, Bernhard, McCarthy, Neil E, Eberl, Matthias

“…Direct interaction between T-cells exerts a major influence on tissue immunity and inflammation across multiple body sites including the human gut, which is…”
Get full text

CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue: e1004641 by Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A, Snelgrove, Robert J, Lacaze, Paul, Jacques, Laura C, Cuff, Simone M, Stanton, Richard J, Gallimore, Awen M, Hussell, Tracy, Wilkinson, Gavin WG, Ghazal, Peter, Taylor, Philip R, Humphreys, Ian R

“…CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200…”
Get full text