Search Results - "Cuevas, N"

Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem by Gingras, Alexandre R, Lagarrigue, Frederic, Cuevas, Monica N, Valadez, Andrew J, Zorovich, Marcus, McLaughlin, Wilma, Lopez-Ramirez, Miguel Alejandro, Seban, Nicolas, Ley, Klaus, Kiosses, William B, Ginsberg, Mark H

“…Rap1 GTPases bind effectors, such as RIAM, to enable talin1 to induce integrin activation. In addition, Rap1 binds directly to the talin1 F0 domain (F0);…”
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Baseline levels of environmental genotoxicity and potential confounding factors using common sole (Solea solea) as sentinel organism by Cuevas, N., Zorita, I.

“…Micronuclei (MN) and nuclear buds (NB) frequency was assessed monthly over a one-year period in erythrocytes of common soles (Solea solea) from the Basque…”
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Occupational asthma induced by fish exposure by Añibarro, B, Feijoo, L, de las Cuevas, N, Seoane, F J

“…Summary Occupational asthma triggered by inhaling fish-derived aerosols is estimated to affect 2–8% of exposed individuals. This primarily affects workers in…”
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High Plasticity of New Granule Cells in the Aging Hippocampus by Trinchero, Mariela F., Buttner, Karina A., Sulkes Cuevas, Jessica N., Temprana, Silvio G., Fontanet, Paula A., Monzón-Salinas, M. Cristina, Ledda, Fernanda, Paratcha, Gustavo, Schinder, Alejandro F.

“…During aging, the brain undergoes changes that impair cognitive capacity and circuit plasticity, including a marked decrease in production of adult-born…”
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Multi-annual survey of health status disturbance in the Bilbao estuary (Bay of Biscay) based on sediment chemistry and juvenile sole (Solea spp.) histopathology by Briaudeau, T., Zorita, I., Cuevas, N., Franco, J., Marigómez, I., Izagirre, U.

“…The Bilbao estuary (SE Bay of Biscay) is a recovering ecosystem whose sediments are still contaminated. They represent a potential risk for the biota including…”
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Multi-organ histopathology in gobies for estuarine environmental risk assessment: A case study in the Ibaizabal estuary (SE Bay of Biscay) by Cuevas, N., Zorita, I., Franco, J., Costa, P.M., Larreta, J.

“…Multi-organ (liver, gills, kidney and spleen) histopathology in gobies (Pomatoschistus spp.) together with metal bioaccumulation and sediment contamination…”
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Explorations on the ecological role of toxin secretion and delivery in jawless predatory Polychaeta by Cuevas, N., Martins, M., Rodrigo, A. P., Martins, C., Costa, P. M.

“…Motivated by biotechnological prospects, there is increasing evidence that we may just be scraping the tip of the iceberg of poisonous marine invertebrates,…”
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Histopathological baseline levels and confounding factors in common sole (Solea solea) for marine environmental risk assessment by Cuevas, N., Zorita, I., Costa, P.M., Larreta, J., Franco, J.

“…Liver and gonad histopathology, biometric parameters and hepatic metal bioaccumulation were assessed monthly over a one-year period in common soles from the…”
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Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer's Disease by Toledo, Juan P, Fernández-Pérez, Eduardo J, Ferreira, Ildete L, Marinho, Daniela, Riffo-Lepe, Nicolas O, Pineda-Cuevas, Benjamin N, Pinochet-Pino, Luis F, Burgos, Carlos F, Rego, A Cristina, Aguayo, Luis G

“…Alzheimer's disease (AD) is the most common cause of senile dementia worldwide, characterized by both cognitive and behavioral deficits. Amyloid beta peptide…”
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In vitro studies of water-stable cationic carbosilane dendrimers as delivery vehicles for gene therapy against HIV and hepatocarcinoma by de Las Cuevas, N, Garcia-Gallego, S, Rasines, B, de la Mata, F J, Guijarro, L G, Muñoz-Fernández, M Á, Gómez, R

“…Here we present a synthetic procedure for water-stable carbosilane dendrimers containing ammonium groups at the periphery of type…”
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Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation by Lagarrigue, Frederic, Gingras, Alexandre R., Paul, David S., Valadez, Andrew J., Cuevas, Monica N., Sun, Hao, Lopez-Ramirez, Miguel A., Goult, Benjamin T., Shattil, Sanford J., Bergmeier, Wolfgang, Ginsberg, Mark H.

“…Activation of platelet glycoprotein IIb-IIIa (GPIIb-IIIa; integrin αIIbβ3) leads to high-affinity fibrinogen binding and platelet aggregation during…”
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Assessment of the Relationship Between Inflammation and Glomerular Filtration Rate by Ramirez-Gonzalez, J. B., Morales-BuenRostro, L. E., Garcia-Covarrubias, L., Pacheco-Domínguez, R. L., Durazo-Arvizu, R., Cuevas-Medina, E. N., Furuzawa-Carballeda, J., Osorio-Juárez, R. A., Correa-Rotter, R., Rincón-Pedrero, R., Alberú-Gómez, Josefina, López Cervantes, Malaquías

“…Background: Chronic kidney disease (CKD) is a global health problem. As it progresses to end stages, renal replacement therapy is required but ultimately, the…”
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Identification and evaluation of inhibitors of the EhGEF1 protein from Entamoeba histolytica by Hernández-Cuevas, N. A., Hernandez-Rivas, R., Sosa-Peinado, A., Rojo-Domínguez, A., Vargas, M.

“…The Dbl family of guanine nucleotide exchange factors (GEFs) is made up of a vast array of members that participate in the activation of the Rho family of…”
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EhNCABP166: A nucleocytoplasmic actin-binding protein from Entamoeba histolytica by Campos-Parra, A.D., Hernández-Cuevas, N.A., Hernandez-Rivas, R., Vargas, M.

“…The actin cytoskeleton consists of multiple actin binding proteins (ABPs) that participate cooperatively in different cellular functions such as the…”
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Gene promoter hypermethylation in oral rinses of leukoplakia patients—a diagnostic and/or prognostic tool? by López, M, Aguirre, J.M, Cuevas, N, Anzola, M, Videgain, J, Aguirregaviria, J, Martı́nez de Pancorbo, M

“…Leukoplakia is the most frequent oral precancerous lesion and shows a variable rate of malignant transformation. We hypothesised that the detection of…”
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C0031: Pulmonary Artery Thromboembolism in Oncologic Children by Conde Cuevas, N, García Aldana, D, Benítez Carabante, M.I, Varo Rodríguez, A, Martínez de Sancha, A, Calvo, C, Fernández-Tejeiro Álvarez, A

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Talin-1 is the principal platelet Rap1 effector of integrin activation by Lagarrigue, Frederic, Paul, David S., Gingras, Alexandre R., Valadez, Andrew J., Sun, Hao, Lin, Jenny, Cuevas, Monica N., Ablack, Jailal N., Lopez-Ramirez, Miguel Alejandro, Bergmeier, Wolfgang, Ginsberg, Mark H.

“…Ras-related protein 1 (Rap1) is a major convergence point of the platelet-signaling pathways that result in talin-1 binding to the integrin β cytoplasmic…”
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Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients by Cuevas, Natividad de las, Muñoz, Úrsula, Hermida, Ofelia G., Martín-Requero, Ángeles

“…Cell cycle disturbances may precede neuronal death in Alzheimer's disease (AD). We described alterations, in lymphocytes from AD patients, on the activity of…”
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Impaired apoptosis in lymphoblasts from Alzheimer's disease patients: cross-talk of Ca2+/calmodulin and ERK1/2 signaling pathways by Bartolomé, F, de Las Cuevas, N, Muñoz, U, Bermejo, F, Martín-Requero, A

“…We have analyzed the intracellular signals that allow lymphoblasts from Alzheimer's disease (AD) patients to escape from serum deprivation-induced apoptosis…”
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P0493 BODY MASS INDEX AND CARDIOVASCULAR RISK ESTIMATED IN SPANISH POPULATION by Cuevas, N, Recarte, Carlos, Salomon, Roberto, Villalba, Maria Victoria, Vilalta, Encarnación, Salor, Diana, Ferrer, Maria, Marin, Olga, Oliveros, Eduardo, Millan, Jesus

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