Search Results - "Cueva, Juan Fernando"

An olaparib window-of-opportunity trial in patients with early-stage endometrial carcinoma: POLEN study by Romero, Ignacio, Rubio, M. Jesús, Medina, Manuel, Matias-Guiu, Xavier, Santacana, Maria, Schoenenberger, Juan-Antonio, Guerra, Eva Maria, Cortés, Alfonso, Minig, Lucas, Coronado, Pluvio, Cueva, Juan Fernando, Gómez, Lourdes, Malfettone, Andrea, Sampayo, Miguel, Llombart-Cussac, Antonio, Poveda, Andrés

“…Olaparib is a potent inhibitor of poly(ADP-ribose) polymerase (PARP)-1, 2, and 3 with potential activity in endometrial cancer (EC). In this…”
Get full text

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial by Gladieff, Laurence, Martínez-García, Jerónimo, Villacampa, Guillermo, Takekuma, Munetaka, De Giorgi, Ugo, Lindemann, Kristina, Woelber, Linn, Colombo, Nicoletta, Duska, Linda, Leary, Alexandra, Godoy-Ortiz, Ana, Angelergues, Antoine, Rubio, Maria Jesús, Fariñas-Madrid, Lorena, Lorusso, Domenica, Ray-Coquard, Isabelle, Manso, Luis, Joly, Florence, Alarcón, Jesús, Follana, Philippe, Romero, Ignacio, Lebreton, Coriolan, Pérez-Fidalgo, J Alejandro, Yunokawa, Mayu, Dahlstrand, Hanna, Abadie-Lacourtoisie, Sophie, Anzizar, Nerea, Aoki, Daiseuke, Barretina-Ginesta, Maria-Pilar, Battista, Marco, Bentzen, Anne Gry, Berton, Dominique, Bjørge, Line, Bjurberg, Maria, Bologna, Alessandra, Casanova, Claudia, Chekerov, Radoslav, Chevalier, Annick, Cueva, Juan Fernando, Czogalla, Bastian, Delanoy, Nicolas, Denschlag, Dominik, Derke, Oscar, Eichbaum, Michael, Enomoto, Takayuki, Esteban, Carmen, Fabbro, Michel, Fehm, Tanja, Ferrero, Annamaria, Fleisch, Markus, Floquet, Anne, Frassoldati, Antonio, Gaba, Lydia, Gadducci, Angiolo, García, Yolanda, Geuna, Elena, Hanker, Lars, Hardy-Bessard, Anne-Claire, Harter, Philipp, Hasegawa, Kosei, Hellman, Kristina, Herrero, Ana, Hilpert, Felix, Katsaros, Dionyssios, Koegel, Matthias, Koliadi, Anthoula, Kurtz, Jean-Emmanuel, Lampe, Bjoern, Lissoni, Andrea Alberto, Lortholary, Alain, Mangili, Giorgia, Mansi, Laura, Marmé, Frederik, Mathews, Cara, Mina, William, Nagao, Shoji, Nishino, Koji, Nishio, Hiroshi, Nishio, Shin, Oaknin, Ana, Onstad, Michaela, Pardo, Beatriz, Pisano, Carmela, Poveda, Andrés, Radosa, Julia, Randall, Leslie M., Ray-Coquard, Isabelle, Richardson, Debra, Romero, Ignacio, Ronzino, Graziana, Rubio, Maria Jesús, Selle, Frederic, Takekuma, Munetaka, Takeshima, Nobuhiro, Tewari, Krishnansu, Todo, Yukiharu, Wimberger, Pauline, Woelber, Linn, You, Benoît, Yunokawa, Mayu

“…The GOG240 trial established bevacizumab with chemotherapy as standard first-line therapy for metastatic or recurrent cervical cancer. In the BEATcc trial…”
Get full text

Phase II clinical trial assessing the efficacy of enzalutamide in advanced non-resectable granulosa cell ovarian tumors: The GREKO III study (GETHI2016–01) by García-Donas, Jesus, Redondo, Andres, Santaballa, Ana, Garrigos, Laia, Rubio, Mª. Jesus, Lainez, Nuria, González, María Iglesias, Cueva, Juan Fernando, Barquin, Arantzazu, Grazioso, Tatiana P., Hurtado, Alicia, Sevillano, Elena, Grande, Enrique, Rodriguez-Moreno, Juan Francisco, Navarro, Paloma

“…Granulosa cell ovarian tumors (GCT) are orphan disease with limited treatments. Hormone therapy is a potential treatment, due to the overexpression of hormone…”
Get full text

Atezolizumab and chemotherapy for advanced or recurrent endometrial cancer (AtTEnd): a randomised, double-blind, placebo-controlled, phase 3 trial by Colombo, Nicoletta, Biagioli, Elena, Harano, Kenichi, Galli, Francesca, Hudson, Emma, Antill, Yoland, Choi, Chel Hun, Rabaglio, Manuela, Marth, Christian, Parma, Gabriella, Fariñas-Madrid, Lorena, Nishio, Shin, Allan, Karen, Lee, Yeh Chen, Piovano, Elisa, Pardo, Beatriz, Nakagawa, Satoshi, McQueen, John, Zamagni, Claudio, Manso, Luis, Takehara, Kazuhiro, Ferrero, Annamaria, Tognon, Germana, Lissoni, Andrea Alberto, Petrella, Mariacristina, Laudani, Maria Elena, Uggeri, Sara, Barretina Ginesta, M Pilar, Casanova, Claudia, Arcangeli, Valentina, Antonuzzo, Lorenzo, Gadducci, Angiolo, Cosio, Stefania, McNeish, Ian, Tookman, Laura, Redondo Sanchez, Andrés, Choi, Chel Hun, Baldini, Editta, Palaia, Innocenza, Benedetti Panici, Pierluigi, Takahashi, Nobutaka, Lombard, Janine, Ardizzoia, Antonio, Bologna, Alessandra, Herrero Ibáñez, Ana Maria, Musolino, Antonino, Márquez Vázquez, Raúl, Pietzner, Klaus, Braicu, Elena, Heinzelmann-Schwarz, Viola A., Powell, Melanie, Yokoyama, Yoshihito, Abeni, Chiara, Cueva, Juan Fernando, Trillsch, Fabian, Ataseven, Beyhan, Petru, Edgar, Heubner, MartinLeonhard, Sadozye, Azmat Hassanq, Dubey, Sidharth, Tiley, Susan, Chrystal, Kathryn, Kim, Sang Wun, Fehr, Mathias, Scatchard, Kate, Anand, Anjana, Taylor, Alexandra, Enomoto, Takayuki, Yoshihara, Kosuke, Selva-Nayagam, Sudarsha, Karki, Bhaskar, Wilkinson, Kate, Chantrill, Lorraine, Lee, Chulmin, Bertolini, Alessandro, Narducci, Filomena, Bellotti, Giovanna, Fusco, Vittorio, Aebi, Stefan, Del Grande, Maria, Tokunaga, Hideki, Shigeta, Shogo, Goss, Geraldine, Siow, Zhen Rong, Steer, Christopher, Lee, Kwang-Beom, Di Meglio, Giovanni, Massa, Elena, De Marino, Elvira, Tortora, Vincenzo, Palacio Vazquez, Isabel, Tsuji, Kosuke, Tominaga, Eiichiro, Black, Allison, So, Kyeong A, Suh, Dong Hoon, Lee, Keun Ho, Fossati, Roldano, Carlucci, Luciano, Barberis, Massimo

“…At the time of AtTEnd trial design, standard treatment for advanced or recurrent endometrial cancer included carboplatin and paclitaxel chemotherapy. This…”
Get full text

Laboratory cross-comparison of homologous recombination repair mutation analysis in tumor in a multicenter epithelial ovarian cancer series: The BORNEO GEICO 60-0 study by Romero, Ignacio, Oaknin, Ana, Garcia-Casado, Zaida, Marquez, Raul, Yubero Esteban, Alfonso, Gallego, Alejandro, Sanchez, Ana Beatriz, Pérez Segura, Cristina, Alarcon Company, Jesus, Barretina Ginesta, Pilar, Palacio Vázquez, Isabel, Fariñas Madrid, Lorena, Cueva, Juan Fernando, Matito, Judit, Poveda, Andres, Lopez-Guerrero, Jose Antonio, Vivancos, Ana

“…Abstract only e17550 Background: In epithelial ovarian cancer (EOC), the identification of mutations in homologous recombination repair (HRR) genes on tumor is…”
Get full text

Laboratory cross-comparison of tumor BRCA1/2 analysis in a multicenter epithelial ovarian cancer series: The BORNEO GEICO60-0 study by Romero, Ignacio, Oaknin, Ana, Garcia-Casado, Zaida, Marquez, Raul, Yubero Esteban, Alfonso, Gallego, Alejandro, Sanchez, Ana Beatriz, Perez Segura, Cristina, Alarcon, Jesus, Barretina-Ginesta, Maria Pilar, Palacio Vázquez, Isabel, Farinas-Madrid, Lorena, Cueva, Juan Fernando, Matito, Judit, Poveda, Andres, Lopez Guerrero, Jose Antonio, Vivancos, Ana

“…Abstract only 6055 Background: Epithelial ovarian cancer (EOC) identification of BRCA1 and BRCA2 mutations is usually carried out in germline, representing…”
Get full text

Preoperative olaparib in early-stage endometrial cancer (EC): A phase 0, window of opportunity trial to evaluate the PARP inhibition effect, targeting cell cycle-related proteins (POLEN study) by Romero, Ignacio, Rubio, M. Jesús, Medina, Manuel, Serrano, Raquel, Guerra, Eva Mª, Salgado, Alfonso Cortes, Pérez, Belén, Minig, Lucas, Casado, Antonio, Coronado, Pluvio, Cueva, Juan Fernando, Vilar, Ana, Torné, Aureli, Ordi, Jaume, Cros, Sara, Salinas, Gaspar, Santacana, Maria, Schoenenberger-Arnaiz, Juan Antonio, Llombart-Cussac, Antonio, Poveda, Andres

“…Abstract only…”
Get full text

Preventing alpelisib-related hyperglycaemia in HR+/HER2−/PIK3CA-mutated advanced breast cancer using metformin (METALLICA): a multicentre, open-label, single-arm, phase 2 trialResearch in context by Antonio Llombart-Cussac, José Manuel Pérez-Garcia, Manuel Ruiz Borrego, Pablo Tolosa, Salvador Blanch, Adela Fernández-Ortega, Ander Urruticoechea, Isabel Blancas, Cristina Saura, Beatriz Rojas, Begoña Bermejo, José Ponce Lorenzo, María Gion, Patricia Cortez-Castedo, Elisenda Llabres, Elena Galve, Juan Fernando Cueva, Ana López, José Luis Alonso-Romero, Santiago González-Santiago, Eduardo Martínez de Dueñas, Eva Ciruelos, Griselda Martrat, Petra Gener, Daniel Alcalá-López, Miguel Sampayo-Cordero, Fernando Gómez-Peralta, Javier Cortés

“…Background: Hyperglycaemia is an early and frequent adverse event during alpelisib treatment. METALLICA aimed to evaluate prophylactic metformin to prevent or…”
Get full text

Open label phase II clinical trial of orteronel (TAK-700) in metastatic or advanced non-resectable granulosa cell ovarian tumors: The Greko II study by García-Donas, Jesús, Garrigos, Laia, Lainez, Nuria, Santaballa, Ana, Redondo, Andres, Cueva, Juan Fernando, Rubio, M Jesus, Prieto, Mario, Lopez-Guerrero, Jose Antonio, Garcia-Casado, Zaida, Grande, Enrique, Guerra Alia, Eva, Bover, Isabel, Hernando Polo, Susana, Sanchez-escribano, Ricardo, Hurtado, Alicia, Navarro, Paloma, Rodriguez-Moreno, Juan Francisco

“…Abstract only 5577 Background: Granulosa-cell tumors (GCT) of the ovary are a rare entity characterized by presenting a punctual mutation at the FOXL2 gene…”
Get full text

Abstract PD8-02: Metformin (MET) for the prevention of Alpelisib (ALP)-related Hyperglycemia (HG) in PIK3CA-mutated, Hormone Receptor-Positive (HR[+]) HER2-Negative (HER2[-]) Advanced Breast Cancer (ABC): The METALLICA study by Borrego, Manuel Ruiz, Tolosa, Pablo, Blanch, Salvador, Fernández, Adela, Urriticoechea, Ander, Blancas, Isabel, Saura, Cristina, Rojas, Beatriz, Bermejo, Begoña, Ponce, Jose, Gión, Maria, Llabres, Elisenda, Galve, Elena, Cueva, Juan Fernando, López, Ana, Alonso-Romero, José L, González-Santiago, Santiago, De Dueñas, Eduardo Martínez, Peralta, Fernando Gomez, Ciruelos, Eva, Pérez-García, José Manuel, Llombart-Cussac, Antonio, Cortés, Javier

“…Abstract Background: HG is an on-target AE of PI3K inhibition, reported in 63.7% (36.6% G≥3) of HR[+]/HER2[-] ABC patients (pts) treated with ALP plus…”
Get full text

Preventing alpelisib-related hyperglycaemia in HR+/HER2−/PIK3CA-mutated advanced breast cancer using metformin (METALLICA): a multicentre, open-label, single-arm, phase 2 trial by Llombart-Cussac, Antonio, Pérez-Garcia, José Manuel, Ruiz Borrego, Manuel, Tolosa, Pablo, Blanch, Salvador, Fernández-Ortega, Adela, Urruticoechea, Ander, Blancas, Isabel, Saura, Cristina, Rojas, Beatriz, Bermejo, Begoña, Ponce Lorenzo, José, Gion, María, Cortez-Castedo, Patricia, Llabres, Elisenda, Galve, Elena, Cueva, Juan Fernando, López, Ana, Alonso-Romero, José Luis, González-Santiago, Santiago, Martínez de Dueñas, Eduardo, Ciruelos, Eva, Martrat, Griselda, Gener, Petra, Alcalá-López, Daniel, Sampayo-Cordero, Miguel, Gómez-Peralta, Fernando, Cortés, Javier

“…Hyperglycaemia is an early and frequent adverse event during alpelisib treatment. METALLICA aimed to evaluate prophylactic metformin to prevent or reduce…”
Get full text

Open label phase II clinical trial of orteronel (TAK-700) in metastatic or advanced non-resectable granulosa cell ovarian tumors: The Greko II study—GETHI 2013-01 by Rodriguez-Moreno, Jf, García-Donas, Jesús, Garrigos, Laia, Laínez, Nuria, Santaballa, Ana, Redondo, Andrés, Cueva, Juan Fernando, Rubio, Maria Jesus, Hernando Polo, Susana, Bover, Isabel, Palacio, Isabel, Garcia-Casado, Zaida, Grande, Enrique, Hurtado, Alicia

“…Abstract only…”
Get full text

Open-label phase II clinical trial of orteronel (TAK-700) in metastatic or advanced nonresectable granulosa cell ovarian tumors: The GREKO II study by Garrigos, Laia, Santaballa, Ana, Hurtado, Alicia, Rodriguez-Moreno, Juan Francisco, Sanchez-escribano, Ricardo, Redondo, Andres, Lainez, Nuria, Rubio, M Jesus, Bover, Isabel, Cueva, Juan Fernando, Hernando Polo, Susana, Izquierdo Manuel, Marta, Prieto, Mario, Lopez-Guerrero, Jose Antonio, Garcia-Casado, Zaida, Perez, Ignacio, De Las Penas, Ramon, Grande, Enrique, García-Donas, Jesús

“…Abstract only…”
Get full text

Neoadjuvant chemotherapy followed by chemoradiation in selected locally advanced squamous cervical cancer by Cueva, Juan Fernando, Martinez Lago, Nieves, Vieito, Maria, Gonzalez Patino, Ezequiel, Curiel Garcia, Maria Teresa, salvador Garrido, Nuria, Palacios Ozores, Patricia, Candamio, Sonia, López López, Rafael

“…Abstract only 5603 Background: Although there has not been a direct comparison between neoadjuvant chemotherapy followed by chemoradiation with chemoradiation…”
Get full text

Open-label phase II clinical trial of orteronel (TAK-700) in metastatic or advanced nonresectable granulosa cell ovarian tumors: The GREKO II study by Hurtado, Alicia, García-Donas, Jesús, Garrigos, Laia, Laínez, Nuria, Redondo, Andres, Cueva, Juan Fernando, Santaballa, Ana, Rubio, Maria Jesus, Palacio, Isabel, Bover, Isabel, Lopez-Guerrero, Jose Antonio, Prieto, Mario, Garcia-Casado, Zaida, Hernando Polo, Susana, Romero, Nuria, Grande, Enrique

“…Abstract only…”
Get full text

Ketoconazole as inhibitor of the enzyme CYP17 in locally advanced or disseminated granulosa cell tumors of the ovary (the GreKo I study) (gethi 11-03) by Garrigos, Laia, Hurtado, Alicia, Santaballa, Ana, Redondo, Andrés, Laínez, Nuria, Vidal Boixader, Laura, Guerra Alia, Eva, Rodriguez, Victor, Cueva, Juan Fernando, Bover, Isabel, Palacio, Isabel, Rubio, M Jesus, Prieto, Mario, Lopez-Guerrero, Jose Antonio, Romero, Nuria, Garcia-Casado, Zaida, García-Martínez, Elena, Grande, Enrique, García-Donas, Jesús

“…Abstract only…”
Get full text

Comprehensive management of cervical cancer by Cueva Bañuelos, Juan Fernando, Palacios Ozores, Patricia, Arias Baltar, María Efigenia, Rodríguez López, Carmela, Pereiro Corbacho, Diego, Curiel Garcia, María Teresa, Cortegoso Mosquera, Alexandra, Couselo Paniagua, María de la Luz, Vilar Lagares, Ana, Varela Pazos, Ana María

Get full text

Metastatic and unresectable biliary tract tumors: A single-center retrospective review by Vieito, Maria, Martinez Lago, Nieves, Aguin Losada, Santiago, Lopez, Rafael, Candamio, Sonia, Brozos Vazquez, Elena Maria, Gallardo, Elena, Varela Ponte, Rafael, Anido, Urbano, Vazquez, Francisca, Vidal, Yolanda, Cueva Banuelos, Juan Fernando, Campos, Marta Carmona, Rodriguez Lopez, Carmela

“…Abstract only e14733 Background: Biliary tract tumours are rare and often poor prognosis cancers that comprise cholangiocarcinomas, ampullary tumours and…”
Get full text

Experiencia de un comité de ética de la investigación durante la pandemia por COVID-19 by Fernández Rial, José Álvaro, Ferreira Díaz, Mª José, Cruz del Río, Juana, Romero Yuste, Susana, Bugarín González, Rosendo, Fernández Trisac, José Luis, Millán Calenti, Rafael Alvaro, Vázquez Lago, J.M, López Vázquez, Paula María, Cueva Bañuelos, Juan Fernando, Santos García, Diego, Rodríguez-Tenreiro Sánchez, María del Carmen, Zarra Ferro, Irene, Pía Morandeira, Agustín, Verdejo González, Asunción, Prado Casal, Jorge, Casariego Rosón, Juan, Carballeda Feijóo, Nuria

“…Background: The health crisis caused by COVID-19 required the prompt launch of research in order to generate scientific evidence pertaining to the new disease…”
Get full text

Ethics Committee experience during COVID-19 emergency. A brief report. by Bugarín González, Rosendo, Romero-Yuste, Susana María, López Vázquez, Paula Mª, Casariego Rosón, Juan, Carballeda Feijóo, Nuria, Cruz Del Río, Juana Mª, Cueva Bañuelos, Juan Fernando, Fernández Rial, José Álvaro, Fernández Trisac, José Luis, Ferreira Díaz, Mª José, Millán Calenti, Rafael Álvaro, Pía Morandeira, Agustín, Prado Casal, Jorge, Rodríguez-Tenreiro Sánchez, Carmen, Santos García, Diego, Vázquez Lago, Juan Manuel, Verdejo González, Mª Asunción, Zarra Ferro, Irene

“…The health crisis caused by COVID-19 required the prompt launch of research in order to generate scientific evidence pertaining to the new disease oriented to…”
Get more information