Search Results - "Cuellar, Mauricio"

Design, synthesis, antifungal activity, and structure–activity relationship studies of chalcones and hybrid dihydrochromane–chalcones by Mellado, Marco, Espinoza, Luis, Madrid, Alejandro, Mella, Jaime, Chávez-Weisser, Eduardo, Diaz, Katy, Cuellar, Mauricio

“…A series of ten chalcones ( 7a–j ) and five new dihydrochromane–chalcone hybrids ( 7k–o ) were synthesized and identified using spectroscopic techniques (IR,…”
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New Brassinosteroid Analogs with 23,24-Dinorcholan Side Chain, and Benzoate Function at C-22: Synthesis, Assessment of Bioactivity on Plant Growth, and Molecular Docking Study by Aitken, Vanessa, Diaz, Katy, Soto, Mauricio, Olea, Andrés F, Cuellar, Mauricio A, Nuñez, Maria, Espinoza-Catalán, Luis

“…The synthesis and biological evaluation of brassinosteroids (BRs) analogs with chemical modification in the side alkyl chain is a matter of current interest…”
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Novel Brassinosteroid Analogues with 3,6 Dioxo Function, 24-Nor-22( S )-Hydroxy Side Chain and p -Substituted Benzoate Function at C-23-Synthesis and Evaluation of Plant Growth Effects by Jorquera, Sebastián, Soto, Mauricio, Díaz, Katy, Nuñez, María, Cuellar, Mauricio A, Olea, Andrés F, Espinoza-Catalán, Luis

“…Brassinosteroids (BRs) are an important group of polyhydroxylated naturally occurring steroidal phytohormones found in the plant kingdom in extremely low…”
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Antimicrobial Activity of Drimanic Sesquiterpene Compounds from Drimys winteri against Multiresistant Microorganisms by Montenegro, Iván, Pazmiño, Rolando, Araque, Ileana, Madrid, Alejandro, Besoain, Ximena, Werner, Enrique, Espinoza-Catalán, Luis, Olea, Andrés F, Parra, Claudio, Navarrete Molina, Valentina, Godoy, Patricio, Olguín, Yusser, Cuellar, Mauricio A

“…In this work, a group of ten sesquiterpene drimanes, including polygodial ( ), isopolygodial ( ), and drimenol ( ) obtained from the bark of F. and seven…”
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Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol by Araque, Ileana, Ramírez, Javiera, Vergara, Rut, Mella, Jaime, Aránguiz, Pablo, Espinoza, Luis, Vera, Waleska, Montenegro, Iván, Salas, Cristian O, Villena, Joan, Cuellar, Mauricio A

“…In this study, we aimed to evaluate two sets of sesquiterpene-aryl derivatives linked by an ester bond, their cytotoxic activities, and their capacity to…”
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Chemical Analysis and In Vitro Bioactivity of Essential Oil of Laurelia sempervirens and Safrole Derivatives against Oomycete Fish Pathogens by Madrid, Alejandro, Morales, Ana Lizeth, Saffirio, Valentina, Cuellar, Mauricio A, Werner, Enrique, Said, Bastián, Godoy, Patricio, Caro, Nelson, Melo, Mirna, Montenegro, Iván

“…In this study, the essential oil (EO) from was analyzed by GC/MS and safrole ( ) was identified as the major metabolite , was subjected to direct reactions on…”
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Effect of Cannabis sativa L. extracts, phytocannabinoids and their acetylated derivates on the SHSY-5Y neuroblastoma cells' viability and caspases 3/7 activation by Tapia-Tapia, Elizabeth, Aránguiz, Pablo, Diaz, Rodrigo, Espinoza, Luis, Weinstein-Oppenheimer, Caroline R, Cuellar, Mauricio

“…There is a need for novel treatments for neuroblastoma, despite the emergence of new biological and immune treatments, since refractory pediatric neuroblastoma…”
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(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of Angucyclinones by Quiñones, Natalia, Hernández, Santiago, Espinoza Catalán, Luis, Villena, Joan, Brito, Ivan, Cabrera, Alan R, Salas, Cristian O, Cuellar, Mauricio A

“…We describe the syntheses of nine new angucyclinone 6-aza-analogues, achieved through a hetero Diels-Alder reaction between the shikimic acid…”
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Synthesis of New Brassinosteroid 24-Norcholane Type Analogs Conjugated in C-3 with Benzoate Groups by Ferrer, Karoll, Díaz, Katy, Kvasnica, Miroslav, Olea, Andrés F, Cuellar, Mauricio, Espinoza, Luis

“…The metabolism of brassinosteroid leads to structural modifications in the ring skeleton or the side alkyl chain. The esterification and glycosylation at C-3…”
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Cytotoxic Effects on Breast Cancer Cell Lines of Chalcones Derived from a Natural Precursor and Their Molecular Docking Analysis by Bustos, Luis, Echiburú-Chau, Carlos, Castro-Alvarez, Alejandro, Bradshaw, Ben, Simirgiotis, Mario J., Mellado, Marco, Parra, Claudio, Cuellar, Mauricio

“…This study aimed to determine the in vitro cytotoxicity and understand possible cytotoxic mechanisms via an in silico study of eleven chalcones synthesized…”
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New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase by Espinosa-Bustos, Christian, Ortiz Pérez, Mariana, Gonzalez-Gonzalez, Alonzo, Zarate, Ana María, Rivera, Gildardo, Belmont-Díaz, Javier A., Saavedra, Emma, Cuellar, Mauricio A., Vázquez, Karina, Salas, Cristian O.

“…To develop novel chemotherapeutic alternatives for the treatment of Chagas disease, in this study, a set of new amino naphthoquinone derivatives were…”
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Biopesticide Activity from Drimanic Compounds to Control Tomato Pathogens by Montenegro, Iván, Madrid, Alejandro, Cuellar, Mauricio, Seeger, Michael, Alfaro, Juan Felipe, Besoain, Ximena, Martínez, Juan Pablo, Ramirez, Ingrid, Olguín, Yusser, Valenzuela, Miryam

“…Tomato crops can be affected by several infectious diseases produced by bacteria, fungi, and oomycetes. Four phytopathogens are of special concern because of…”
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Chemical Characterization and Anti-Oomycete Activity of Laureliopsis philippianna Essential Oils against Saprolegnia parasitica and S. australis by Madrid, Alejandro, Godoy, Patricio, González, Sebastián, Zaror, Luis, Moller, Alejandra, Werner, Enrique, Cuellar, Mauricio, Villena, Joan, Montenegro, Iván

“…Laureliopsis philippiana (Looser) R. Schodde (Monimiaceae) is a native tree widespread in the forest areas in the south of Chile and Argentina, known for its…”
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Antifeedant effect of polygodial and drimenol derivatives against Spodoptera frugiperda and Epilachna paenulata and quantitative structure‐activity analysis by Montenegro, Iván J, del Corral, Soledad, Diaz Napal, Georgina N, Carpinella, María C, Mellado, Marco, Madrid, Alejandro M, Villena, Joan, Palacios, Sara M, Cuellar, Mauricio A

“…BACKGROUND The antifeedant activity of 18 sesquiterpenoids of the drimane family (polygodial, drimenol and derivatives) was investigated. RESULTS Polygodial,…”
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QSAR‐driven synthesis of antiproliferative chalcones against SH‐SY5Y cancer cells: Design, biological evaluation, and redesign by Mellado, Marco, Reyna‐Jeldes, Mauricio, Weinstein‐Oppenheimer, Caroline, Covarrubias, Alejandra A., Aguilar, Luis F., Coddou, Claudio, Mella, Jaime, Cuellar, Mauricio A.

“…Neuroblastoma is one of the most frequent types of cancer found in infants, and traditional chemotherapy has limited efficacy against this pathology. Thus, the…”
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Synthesis and Evaluation of Novel Oxyalkylated Derivatives of 2',4'-Dihydroxychalcone as Anti-Oomycete Agents against Bronopol Resistant Strains of Saprolegnia sp by Flores, Susana, Montenegro, Iván, Villena, Joan, Cuellar, Mauricio, Werner, Enrique, Godoy, Patricio, Madrid, Alejandro

“…A series of novel oxyalkylchalcones substituted with alkyl groups were designed and synthesized, and the antioomycete activity of the series was evaluated in…”
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Structural requirements for the antifungal activities of natural drimane sesquiterpenes and analogues, supported by conformational and electronic studies by Derita, Marcos, Montenegro, Iván, Garibotto, Francisco, Enriz, Ricardo D, Fritis, Mauricio Cuellar, Zacchino, Susana A

“…Seventeen drimanes including polygodial (1), isopolygodial (2), drimenol (3) and confertifolin (4) obtained from natural sources and the semi-synthetic…”
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Study on the cytotoxic activity of drimane sesquiterpenes and nordrimane compounds against cancer cell lines by Montenegro, Ivan, Tomasoni, Giacomo, Bosio, Claudia, Quiñones, Natalia, Madrid, Alejandro, Carrasco, Hector, Olea, Andres, Martinez, Rolando, Cuellar, Mauricio, Villena, Joan

“…Twelve drimanes, including polygodial (1), isopolygodial (2), drimenol (3), confertifolin (4), and isodrimenin (5), were obtained from natural sources…”
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2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity by Apablaza, Gastón, Montoya, Luisa, Morales-Verdejo, Cesar, Mellado, Marco, Cuellar, Mauricio, Lagos, Carlos F, Soto-Delgado, Jorge, Chung, Hery, Pessoa-Mahana, Carlos David, Mella, Jaime

“…The β₃ adrenergic receptor is raising as an important drug target for the treatment of pathologies such as diabetes, obesity, depression, and cardiac diseases…”
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Comparative study on the larvicidal activity of drimane sesquiterpenes and nordrimane compounds against Drosophila melanogaster til-til by Montenegro, Ivan, Pino, Luis, Werner, Enrique, Madrid, Alejandro, Espinoza, Luis, Moreno, Luis, Villena, Joan, Cuellar, Mauricio

“…Natural compounds from Drimys winteri Forst and derivatives exhibited larvicidal effects against Drosophila melanogaster til-til. The most active compound was…”
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