Search Results - "Cubells, Joseph"

The Gut Microbiome: A New Frontier in Autism Research by Mulle, Jennifer G., Sharp, William G., Cubells, Joseph F.

“…The human gut harbors a complex community of microbes that profoundly influence many aspects of growth and development, including development of the nervous…”
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Epigenetic modification of the oxytocin receptor gene: implications for autism symptom severity and brain functional connectivity by Andari, Elissar, Nishitani, Shota, Kaundinya, Gopinath, Caceres, Gabriella A, Morrier, Michael J, Ousley, Opal, Smith, Alicia K, Cubells, Joseph F, Young, Larry J

“…The role of oxytocin in social cognition has attracted tremendous interest in social neuroscience and psychiatry. Some studies have reported improvement in…”
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Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills by Skuse, David H., Lori, Adriana, Cubells, Joseph F., Lee, Irene, Conneely, Karen N., Puura, Kaija, Lehtimäki, Terho, Binder, Elisabeth B., Young, Larry J.

“…The neuropeptides oxytocin and vasopressin are evolutionarily conserved regulators of social perception and behavior. Evidence is building that they are…”
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Trauma exposure and stress-related disorders in inner city primary care patients by Gillespie, Charles F., M.D., Ph.D, Bradley, Bekh, Ph.D, Mercer, Kristie, M.P.H, Smith, Alicia K., Ph.D, Conneely, Karen, Ph.D, Gapen, Mark, Ph.D, Weiss, Tamara, M.D, Schwartz, Ann C., M.D, Cubells, Joseph F., M.D., Ph.D, Ressler, Kerry J., M.D., Ph.D

“…Abstract Objective This study was undertaken to increase understanding of environmental risk factors for posttraumatic stress disorder (PTSD) and major…”
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SPARK: A US Cohort of 50,000 Families to Accelerate Autism Research by Feliciano, Pamela, Daniels, Amy M., Esler, Amy, Gutierrez, Anibal, Nicholson, Amy, Stephens, Alexandra N., Stedman, Amy, Finucane, Brenda, O’Roak, Brian J., Robertson, Beverly E., Rodriguez, Barbara, Van Metre, Bonnie, Bradley, Catherine, Erickson, Craig A., Harkins, Christina, Ochoa-Lubinoff, Cesar, Rosenberg, Cordelia R., Smith, Christopher J., Taylor, Cora M., White, Loran Casey, Walston, Corrie H., Amaral, David G., Coury, Daniel Lee, Sarver, Dustin E., Li, Deana, Berry-Kravis, Elizabeth, Fombonne, Eric J., Hofammann, Eugenia, Wodka, Ericka L., O’Connor, Eirene, Miller, Fiona, Stein, Gail, Hutter, Hanna, Li, Hai, Lechniak, Holly, Schneider, Hoa Lam, Zaydens, Hana, Arriaga, Ivette, Cubells, Joseph F., Cordova, Jeanette M., Gunderson, Jaclyn, McCracken, James T., Michaelson, Jacob J., Neely, Jason, Orobio, Jessica, Piven, Joseph, Tjernagel, Jennifer, Dent, Katherine, Schweers, Kathryn A., Law, J. Kiely, Lowe, Kathryn, O’Brien, Kaela, Smith, Kaitlin, Pawlowski, Katherine G., Pierce, Karen L., Roeder, Katherine, Coppola, Leigh A., Carpenter, Laura, Huang-Storms, Lark Y., Herbert, Lynette M., Simon, Laura, Soorya, Latha V., Wasserburg, Lucy, Lazar, Maya, Currin, Mary Hannah, Heyman, Michelle, Jones, Mark, Jordy, Michelle, Sahin, Mustafa, Siegel, Matthew S., Yinger, Meredith, Hanna, Nathan, Juarez, A. Pablo, Remington, Rick, Schultz, Robert T., Carpenter, Sarah, Eldred, Sara, Francis, Sunday, Horner, Susannah, Lee, Soo J., Mastel, Sarah A., Myers, Vincent J., Amatya, Alpha, Chatha, Ahmad S., Lash, Alex E., Ridenour, Curtis, Stock, Colleen M., Schmidt, Danielle, Butler, Martin E., Carriero, Nicholas, Volfovsky, Natalia, Edgar, Ron, Chin, Wubin, Jensen, William, Krentz, Anthony D., Astrovskaya, Irina, Gibbs, Richard A., Han, Xinwei, Shen, Yufeng, Reichardt, Louis F.

“…The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.org, a dynamic platform that is engaging thousands of individuals with…”
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Reduced amplitude and slowed latency of the acoustic startle response in adolescents and adults with 22q11.2 deletion syndrome by Parker, David Alan, Imes, Sid, Ruban, Gabrielle, Ousley, Opal Yates, Henshey, Brett, Massa, Nicholas M., Walker, Elaine, Cubells, Joseph F., Duncan, Erica

“…22q11.2 deletion syndrome (22q11DS) is one of the most robust genetic predictors of psychosis and other psychiatric illnesses. In this study, we examined…”
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Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder by Smith, Alicia K., Conneely, Karen N., Kilaru, Varun, Mercer, Kristina B., Weiss, Tamara E., Bradley, Bekh, Tang, Yilang, Gillespie, Charles F., Cubells, Joseph F., Ressler, Kerry J.

“…DNA methylation may mediate persistent changes in gene function following chronic stress. To examine this hypothesis, we evaluated African American subjects…”
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Alcohol and alcohol-related harm in China: policy changes needed by TANG, Yi-Lang, XIANG, Xiao-Jun, WANG, Xu-Yi, CUBELLS, Joseph F, BABOR, Thomas F, WEI HAO

“…In China, alcohol consumption is increasing faster than anywhere else in the world. A steady increase in alcohol production has also been observed in the…”
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Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion by Engchuan, Worrawat, Hestand, Matthew S., Heung, Tracy, Johnston, H. Richard, Monfeuga, Thomas, McDonald-McGinn, Donna M., Gur, Raquel E., Morrow, Bernice E., Swillen, Ann, Vorstman, Jacob A. S., Chow, Eva W. C., van den Bree, Marianne, Emanuel, Beverly S., Warren, Stephen T., Chopra, Pankaj, Cutler, David J., Duncan, Richard, Mulle, Jennifer G., Voss, Anna J., Zwick, Michael E., Diacou, Alexander, Guo, Tingwei, Lin, Jhih-Rong, Wang, Tao, Zhang, Zhengdong, Zhao, Yingjie, Marshall, Christian, Jin, Andrea, Lilley, Brenna, Salmons, Harold I., Tran, Oanh, Pardinas, Antonio, Walters, James T. R., Demaerel, Wolfram, Boot, Erik, Butcher, Nancy J., Lowther, Chelsea, Evers, Rens, van Amelsvoort, Therese A. M. J., van Duin, Esther, Vingerhoets, Claudia, Breckpot, Jeroen, Devriendt, Koen, Vogels, Annick, Moss, Edward M., Sharkus, Robert J., Zackai, Elaine H., Calkins, Monica E., Gallagher, Robert S., Gur, Ruben C., Tang, Sunny X., Fritsch, Rosemarie, Ornstein, Claudia, Repetto, Gabriela M., Breetvelt, Elemi, Duijff, Sasja N., Fiksinski, Ania, Niarchou, Maria, Murphy, Kieran C., Prasad, Sarah E., Daly, Eileen M., Gudbrandsen, Maria, Murphy, Declan G., Buzzanca, Antonio, Digilio, Maria C., Pontillo, Maria, Marino, Bruno, Vicari, Stefano, Coleman, Karlene, Cubells, Joseph F., Ousley, Opal Y., Carmel, Miri, Mekori-Domachevsky, Ehud, Michaelovsky, Elena, Weinberger, Ronnie, Weizman, Abraham, Jalbrzikowski, Maria, Armando, Marco, Eliez, Stéphan, Sandini, Corrado, Béna, Frédérique Sloan, Antshel, Kevin M., Fremont, Wanda, Kates, Wendy R., Belzeaux, Raoul, Philip, Nicole, Campbell, Linda E., McCabe, Kathryn L., Hooper, Stephen R., Schoch, Kelly, Shashi, Vandana, Simon, Tony J., Tassone, Flora, Arango, Celso, García-Miñaúr, Sixto, Suñer, Damià H., Raventos-Simic, Jasna, Epstein, Michael P., Williams, Nigel M., Bassett, Anne S.

“…Schizophrenia occurs in about one in four individuals with 22q11.2 deletion syndrome (22q11.2DS). The aim of this International Brain and Behavior 22q11.2DS…”
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Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome by Davies, Robert W., Fiksinski, Ania M., Breetvelt, Elemi J., Williams, Nigel M., Hooper, Stephen R., Monfeuga, Thomas, Bassett, Anne S., Owen, Michael J., Gur, Raquel E., Morrow, Bernice E., McDonald-McGinn, Donna M., Swillen, Ann, Chow, Eva W. C., van den Bree, Marianne, Emanuel, Beverly S., Vermeesch, Joris R., van Amelsvoort, Therese, Arango, Celso, Armando, Marco, Campbell, Linda E., Cubells, Joseph F., Eliez, Stephan, Garcia-Minaur, Sixto, Gothelf, Doron, Kates, Wendy R., Murphy, Kieran C., Murphy, Clodagh M., Murphy, Declan G., Philip, Nicole, Repetto, Gabriela M., Shashi, Vandana, Simon, Tony J., Suñer, Damiàn Heine, Vicari, Stefano, Scherer, Stephen W., Bearden, Carrie E., Vorstman, Jacob A. S.

“…The 22q11.2 deletion syndrome (22q11DS) is associated with a 20–25% risk of schizophrenia. In a cohort of 962 individuals with 22q11DS, we examined the shared…”
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Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults by Binder, Elisabeth B, Bradley, Rebekah G, Liu, Wei, Epstein, Michael P, Deveau, Todd C, Mercer, Kristina B, Tang, Yilang, Gillespie, Charles F, Heim, Christine M, Nemeroff, Charles B, Schwartz, Ann C, Cubells, Joseph F, Ressler, Kerry J

“…CONTEXT In addition to trauma exposure, other factors contribute to risk for development of posttraumatic stress disorder (PTSD) in adulthood. Both genetic and…”
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An epigenetic clock for gestational age at birth based on blood methylation data by Knight, Anna K, Craig, Jeffrey M, Theda, Christiane, Bækvad-Hansen, Marie, Bybjerg-Grauholm, Jonas, Hansen, Christine S, Hollegaard, Mads V, Hougaard, David M, Mortensen, Preben B, Weinsheimer, Shantel M, Werge, Thomas M, Brennan, Patricia A, Cubells, Joseph F, Newport, D Jeffrey, Stowe, Zachary N, Cheong, Jeanie L Y, Dalach, Philippa, Doyle, Lex W, Loke, Yuk J, Baccarelli, Andrea A, Just, Allan C, Wright, Robert O, Téllez-Rojo, Mara M, Svensson, Katherine, Trevisi, Letizia, Kennedy, Elizabeth M, Binder, Elisabeth B, Iurato, Stella, Czamara, Darina, Räikkönen, Katri, Lahti, Jari M T, Pesonen, Anu-Katriina, Kajantie, Eero, Villa, Pia M, Laivuori, Hannele, Hämäläinen, Esa, Park, Hea Jin, Bailey, Lynn B, Parets, Sasha E, Kilaru, Varun, Menon, Ramkumar, Horvath, Steve, Bush, Nicole R, LeWinn, Kaja Z, Tylavsky, Frances A, Conneely, Karen N, Smith, Alicia K

“…Gestational age is often used as a proxy for developmental maturity by clinicians and researchers alike. DNA methylation has previously been shown to be…”
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Visual-Motor Integration Deficits in 3q29 Deletion Syndrome by Pollak, Rebecca M., Burrell, T. Lindsey, Cubells, Joseph F., Klaiman, Cheryl, Murphy, Melissa M., Saulnier, Celine A., Walker, Elaine F., White, Stormi Pulver, Mulle, Jennifer G.

“…3q29 deletion syndrome (3q29del) is associated with neuropsychiatric and neurodevelopmental phenotypes. We previously reported that graphomotor weakness is…”
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Uncovering biologically relevant Autism subtypes using advanced machine learning techniques by Vento, Christopher, Cubells, Joseph, Young, Larry, Andari, Elissar

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Psychosis spectrum symptoms among individuals with schizophrenia-associated copy number variants and evidence of cerebellar correlates of symptom severity by Sefik, Esra, Guest, Ryan M., Aberizk, Katrina, Espana, Roberto, Goines, Katrina, Novacek, Derek M., Murphy, Melissa M., Goldman-Yassen, Adam E., Cubells, Joseph F., Ousley, Opal, Li, Longchuan, Shultz, Sarah, Walker, Elaine F., Mulle, Jennifer G.

“…•The rare copy number variants (CNVs) 3q29Del and 22q11.2Del confer the largest known effect sizes for schizophrenia susceptibility.•While 22q11.2Del's link…”
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Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes by Feliciano, Pamela, Zhou, Xueya, Astrovskaya, Irina, Turner, Tychele N., Wang, Tianyun, Brueggeman, Leo, Barnard, Rebecca, Hsieh, Alexander, Snyder, LeeAnne Green, Muzny, Donna M., Sabo, Aniko, Gibbs, Richard A., Eichler, Evan E., O’Roak, Brian J., Michaelson, Jacob J., Volfovsky, Natalia, Shen, Yufeng, Chung, Wendy K.

“…Autism spectrum disorder (ASD) is a genetically heterogeneous condition, caused by a combination of rare de novo and inherited variants as well as common…”
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Deep psychophysiological phenotyping of adolescents and adults with 22q11.2 deletion syndrome: a multilevel approach to defining core disease processes by Parker, David A, Cubells, Joseph F, Imes, Sid L, Ruban, Gabrielle A, Henshey, Brett T, Massa, Nicholas M, Walker, Elaine F, Duncan, Erica J, Ousley, Opal Y

“…22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal interstitial-deletion disorder, occurring in approximately 1 in 2000 to 6000 live births…”
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Associations between the DBH gene, plasma dopamine β-hydroxylase activity and cognitive measures in Han Chinese patients with schizophrenia by Sun, Zuoli, Ma, Yun, Li, Wenbiao, He, Jing, Li, Jun, Yang, Xue, Mao, Peixian, Cubells, Joseph F, Tang, Yilang

“…Abstract The dopamine (DA) and norepinephrine (NE) systems modulate cognitive function. Dopamine β-hydroxylase (DβH) converts DA to NE, and its activity is…”
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Neonatal DNA methylation patterns associate with gestational age by Schroeder, James W., Conneely, Karen N., Cubells, Joseph F., Kilaru, Varun, Newport, D. Jeffrey, Knight, Bettina T., Stowe, Zachary N., Brennan, Patricia A., Krushkal, Julia, Tylavsky, Frances A., Taylor, Robert N., Adkins, Ronald M., Smith, Alicia K.

“…Risk for adverse neonatal outcome increases with declining gestational age (GA), and changes in DNA methylation may contribute to the relationship between GA…”
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Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort by Fombonne, Eric, Green Snyder, LeeAnne, Daniels, Amy, Feliciano, Pamela, Chung, Wendy

“…This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK…”
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