Search Results - "Cubedo, Elena"

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    Differentiation stage–specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas by Malumbres, Raquel, Sarosiek, Kristopher A., Cubedo, Elena, Ruiz, Jose W., Jiang, Xiaoyu, Gascoyne, Randy D., Tibshirani, Robert, Lossos, Izidore S.

    Published in Blood (16-04-2009)
    “…miRNAs are small RNA molecules binding to partially complementary sites in the 3′-UTR of target transcripts and repressing their expression. miRNAs orchestrate…”
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    Journal Article
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    miR-155 regulates HGAL expression and increases lymphoma cell motility by Dagan, Liat Nadav, Jiang, Xiaoyu, Bhatt, Shruti, Cubedo, Elena, Rajewsky, Klaus, Lossos, Izidore S.

    Published in Blood (12-01-2012)
    “…HGAL, a prognostic biomarker in patients with diffuse large B-cell lymphoma and classic Hodgkin lymphoma, inhibits lymphocyte and lymphoma cell motility by…”
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    Biological profile of new apoptotic agents based on 2,4-pyrido[2,3- d]pyrimidine derivatives by Cordeu, Lucía, Cubedo, Elena, Bandrés, Eva, Rebollo, Amaia, Sáenz, Xabi, Chozas, Hector, Victoria Domínguez, M a, Echeverría, Mikel, Mendivil, Beatriz, Sanmartin, Carmen, Palop, Juan Antonio, Font, María, García-Foncillas, Jesús

    Published in Bioorganic & medicinal chemistry (15-02-2007)
    “…Derivatives of pyrido[2,3- d]pyrimidines are studied as novel compounds with anticancer activity based on proapoptotic mechanisms. The data indicate that the…”
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    Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma by Cubedo, Elena, Gentles, Andrew J., Huang, Chuanxin, Natkunam, Yasodha, Bhatt, Shruti, Lu, Xiaoqing, Jiang, Xiaoyu, Romero-Camarero, Isabel, Freud, Aharon, Zhao, Shuchun, Bacchi, Carlos E., Martínez-Climent, Jose A., Sánchez-García, Isidro, Melnick, Ari, Lossos, Izidore S.

    Published in Blood (07-06-2012)
    “…LMO2 regulates gene expression by facilitating the formation of multipartite DNA-binding complexes. In B cells, LMO2 is specifically up-regulated in the…”
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    New symmetrical quinazoline derivatives selectively induce apoptosis in human cancer cells by Cubedo, Elena, Cordeu, Lucia, Bandres, Eva, Rebollo, Amaia, Malumbres, Raquel, Sanmartin, Carmen, Font, Maria, Palop, Juan Antonio, Gacía-Foncillas, Jesús

    Published in Cancer biology & therapy (01-07-2006)
    “…In the search of new symmetrical derivatives with anticancer activity, we have looked for novel compounds able to induce a selective proapoptotic mechanism in…”
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    The Transcription Factor LMO2 Is a Robust Marker of Vascular Endothelium and Vascular Neoplasms and Selected Other Entities by GRATZINGER, Dita, SHUCHUN ZHAO, WEST, Robert, ROUSE, Robert V, VOGEL, Hannes, CUBEDO GIL, Elena, LEVY, Ronald, LOSSOS, Izidore S, NATKUNAM, Yasodha

    Published in American journal of clinical pathology (01-02-2009)
    “…The transcription factor LMO2 is involved in vascular and hematopoietic development and hematolymphoid neoplasia. We have demonstrated that LMO2 is expressed…”
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    HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration by Lu, Xiaoqing, Chen, Jun, Malumbres, Raquel, Cubedo Gil, Elena, Helfman, David M., Lossos, Izidore S.

    Published in Blood (15-12-2007)
    “…HGAL is a newly identified germinal center (GC)–specific gene whose expression by the tumor cells correlates with a favorable prognosis in patients with…”
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    Abstract 1906: The role of immunogenic SPANX antigens in distinct cancer stem cell subsets within triple negative breast cancers by Shahin, Lauren, Cubedo, Elena, Coats, Ebony, Boyd, Jeff, Azzam, Diana

    Published in Cancer research (Chicago, Ill.) (01-07-2017)
    “…Abstract Breast cancer is the leading cause of death in women, primarily due to metastatic disease rather than the primary tumor. Median survival with…”
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    How we do it: down to up posterior components separation by Robin-Lersundi, Alvaro, Blazquez Hernando, Luis, López-Monclús, Javier, Cruz Cidoncha, Arturo, San Miguel Méndez, Carlos, Jimenez Cubedo, Elena, García-Ureña, Miguel Angel

    Published in Langenbeck's archives of surgery (01-06-2018)
    “…Background Posterior component separation with transversus abdominis release technique is increasingly being used for abdominal wall reconstruction in complex…”
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    Sodium Salicylate Has a Priming Effect When Combined with Azacitidine in Pre-Clinical Models of AML by Deutsch, Yehuda E., Perez, Aymee, Rodrigues, Ana, Blumenthal, Ezra S., Cubedo, Elena, Watts, Justin M., Swords, Ronan T, Zelent, Arthur

    Published in Blood (06-12-2014)
    “…Introduction: Current therapy for acute myeloid leukemia (AML) is inadequate. Treatment of older patients considered unfit for standard induction therapy is…”
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    Abstract LB-160: HDAC9 expression is deregulated in malignant B-cell lymphomas in particular in diffuse large B-cell lymphoma and mantle cell lymphoma by Cubedo, Elena, Gil, Veronica, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R, Vega, Francisco, Zelent, Arthur

    Published in Cancer research (Chicago, Ill.) (01-08-2015)
    “…Abstract Histone Deacetylase 9 (HDAC9) is a class IIa chromatin-modifying enzyme that, within the hematopoietic system, is preferentially expressed in the…”
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    HDAC9 Expression Is Deregulated in Malignant B-Cell Lymphomas in Particular in Diffuse Large B Cell Lymphoma and Mantle Cell Lymphoma by Cubedo, Elena, Gil, Veronica Sylvina, Kim, Chae Hwa, Campuzano-Zuluaga, German, Agarwal, Nitin Kumar, Howell, Louise, Petrie, Kevin R., Vega, Francisco, Zelent, Arthur

    Published in Blood (06-12-2014)
    “…Aberrant epigenetics leading to changes in chromatin structure and patterns of gene expression is an important factor in cancer pathogenesis. Histone…”
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    Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer by Bansal, Nidhi, Bosch, Almudena, Leibovitch, Boris, Pereira, Lutecia, Cubedo, Elena, Yu, Jianshi, Pierzchalski, Keely, Jones, Jace W, Fishel, Melissa, Kane, Maureen, Zelent, Arthur, Waxman, Samuel, Farias, Eduardo

    Published in Oncotarget (12-07-2016)
    “…Triple negative breast cancer (TNBC) frequently relapses locally, regionally or as systemic metastases. Development of targeted therapy that offers significant…”
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    BLIMP1 Downregulates Expression of, LMO2 and HGAL, Proteins Highly Expressed In Germinal Center B Cells and Germinal Center-Derived Lymphomas by Cubedo, Elena, Maurin, Michelle, Wright, Ken, Lossos, Izidore S

    Published in Blood (19-11-2010)
    “…Abstract 4133 Human germinal center–associated lymphoma (HGAL) and LIM domain only-2 (LMO2) are proteins highly expressed in germinal center (GC) B…”
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