Search Results - "Csomós, Krisztián"

Tissue transglutaminase contributes to the all-trans-retinoic acid–induced differentiation syndrome phenotype in the NB4 model of acute promyelocytic leukemia by Csomós, Krisztián, Német, István, Fésüs, László, Balajthy, Zoltán

“…Treatment of acute promyelocytic leukemia (APL) with all-trans-retinoic acid (ATRA) results in terminal differentiation of leukemic cells toward neutrophil…”
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Tissue-transglutaminase contributes to neutrophil granulocyte differentiation and functions by Balajthy, Zoltán, Csomós, Krisztián, Vámosi, György, Szántó, Attila, Lanotte, Michel, Fésüs, László

“…Promyelocytic NB4 leukemia cells undergo differentiation to granulocytes following retinoic acid treatment. Here we report that tissue transglutaminase (TG2),…”
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Lineage Reconstruction of In Vitro Identified Antigen-Specific Autoreactive B Cells from Adaptive Immune Receptor Repertoires by Blazso, Peter, Csomos, Krisztian, Tipton, Christopher M, Ujhazi, Boglarka, Walter, Jolan E

“…The emergence, survival, growth and maintenance of autoreactive (AR) B-cell clones, the hallmark of humoral autoimmunity, leave their footprints in B-cell…”
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PPARγ‐dependent regulation of human macrophages in phagocytosis of apoptotic cells by Majai, Gyöngyike, Sarang, Zsolt, Csomós, Krisztián, Zahuczky, Gábor, Fésüs, László

“…Macrophages acquire their capacity for efficient phagocytosis of apoptotic cells during their differentiation from monocytes. The peroxisome…”
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Evolving Approach to Clinical Cytometry for Immunodeficiencies and Other Immune Disorders by Sadighi Akha, Amir A., Csomós, Krisztián, Ujházi, Boglárka, Walter, Jolán E., Kumánovics, Attila

“…Primary immunodeficiencies were initially identified on the basis of recurrent, severe or unusual infections. Subsequently, it was noted that these diseases…”
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Protein cross-linking by chlorinated polyamines and transglutamylation stabilizes neutrophil extracellular traps by Csomós, Krisztián, Kristóf, Endre, Jakob, Bernadett, Csomós, István, Kovács, György, Rotem, Omri, Hodrea, Judit, Bagoly, Zsuzsa, Muszbek, Laszlo, Balajthy, Zoltán, Csősz, Éva, Fésüs, László

“…Neutrophil extracellular trap (NET) ejected from activated dying neutrophils is a highly ordered structure of DNA and selected proteins capable to eliminate…”
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Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium by Albert, Réka, Veréb, Zoltán, Csomós, Krisztián, Moe, Morten C, Johnsen, Erik O, Olstad, Ole Kristoffer, Nicolaissen, Bjørn, Rajnavölgyi, Eva, Fésüs, László, Berta, András, Petrovski, Goran

“…A simple, reproducible, animal-material free method for cultivating and characterizing cornea limbal epithelial stem cells (LESCs) on human lens capsule (LC)…”
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Impaired B-cell function in ERCC2 deficiency by Rossmanith, Raphael, Sauerwein, Kai, Geier, Christoph B, Leiss-Piller, Alexander, Stemberger, Roman F, Sharapova, Svetlana, Gruber, Robert W, Bergler, Helmut, Verbsky, James W, Csomos, Krisztian, Walter, Jolan E, Wolf, Hermann M

“…Trichothiodystrophy-1 (TTD1) is an autosomal-recessive disease and caused by mutations in , a gene coding for a subunit of the TFIIH transcription and…”
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B cell abnormalities and autoantibody production in patients with partial RAG deficiency by Min, Qing, Csomos, Krisztian, Li, Yaxuan, Dong, Lulu, Hu, Ziying, Meng, Xin, Yu, Meiping, Walter, Jolan E, Wang, Ji-Yang

“…Mutations in the recombination activating gene 1 ( ) and in humans are associated with a broad spectrum of clinical phenotypes, from severe combined…”
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Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene by Wang, Wenjie, Min, Qing, Lai, Nannan, Csomos, Krisztian, Wang, Ying, Liu, Luyao, Meng, Xin, Sun, Jinqiao, Hou, Jia, Ying, Wenjing, Zhou, Qinhua, Sun, Bijun, Hui, Xiaoying, Ujhazi, Boglarka, Gordon, Sumai, Buchbinder, David, Schuetz, Catharina, Butte, Manish, Walter, Jolan E., Wang, Xiaochuan, Wang, Ji-Yang

“…BackgroundActivated phosphoinositide 3 kinase (PI3K) -delta syndrome (APDS) is an inborn error of immunity with variable clinical phenotype of immunodeficiency…”
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Ligase-4 Deficiency Causes Distinctive Immune Abnormalities in Asymptomatic Individuals by Felgentreff, Kerstin, Baxi, Sachin N., Lee, Yu Nee, Dobbs, Kerry, Henderson, Lauren A., Csomos, Krisztian, Tsitsikov, Erdyni N., Armanios, Mary, Walter, Jolan E., Notarangelo, Luigi D.

“…Purpose DNA Ligase 4 (LIG4) is a key factor in the non-homologous end-joining (NHEJ) DNA double-strand break repair pathway needed for V(D)J recombination and…”
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Case Report: Initial Treatment Adjustments and Complications in Ovarian Cancer Patient With Inborn Error of Immunity by Mammadova, Jamila, Redden, Anna, Cruz, Rachel, Ujhazi, Boglarka, Gordon, Sumai, Ellison, Maryssa, Gatewood, Tyra, Duff, Carla, Cannella, Anthony, Somboonwit, Charurut, Sriaroon, Chakrapol, Csomos, Krisztian, Dasso, Joseph F., Harville, Terry, Ismail-Khan, Roohi, Walter, Jolan E.

“…BackgroundPatients with inborn errors of immunity (IEI) have increased risk of developing cancers secondary to impaired anti-tumor immunity. Treatment of…”
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PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells by Majai, Gyöngyike, Sarang, Zsolt, Csomós, Krisztián, Zahuczky, Gábor, Fésüs, László

“…Macrophages acquire their capacity for efficient phagocytosis of apoptotic cells during their differentiation from monocytes. The peroxisome…”
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Corrigendum: Case report: Initial treatment adjustments and complications in ovarian cancer patient with inborn error of immunity by Mammadova, Jamila, Redden, Anna, Cruz, Rachel, Ujhazi, Boglarka, Gordon, Sumai, Ellison, Maryssa, Gatewood, Tyra, Duff, Carla, Cannella, Anthony, Somboonwit, Charurut, Sriaroon, Chakrapol, Csomos, Krisztian, Dasso, Joseph F., Harville, Terry, Ismail-Khan, Roohi, Walter, Jolan E.

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Asymptomatic Infant With Atypical SCID and Novel Hypomorphic RAG Variant Identified by Newborn Screening: A Diagnostic and Treatment Dilemma by Chitty-Lopez, Maria, Westermann-Clark, Emma, Dawson, Irina, Ujhazi, Boglarka, Csomos, Krisztian, Dobbs, Kerry, Le, Khuong, Yamazaki, Yasuhiro, Sadighi Akha, Amir A, Chellapandian, Deepak, Oshrine, Ben, Notarangelo, Luigi D, Sunkersett, Gauri, Leiding, Jennifer W, Walter, Jolan E

“…The T-cell receptor excision circle (TREC) assay detects T-cell lymphopenia (TCL) in newborns and is especially important to identify severe combined…”
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Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis by Walter, Jolan E., MD, PhD, Lo, Mindy S., MD, PhD, Kis-Toth, Katalin, PhD, Tirosh, Irit, MD, Frugoni, Francesco, MS, Lee, Yu Nee, PhD, Csomos, Krisztian, PhD, Chen, Karin, MD, Pillai, Shiv, MD, PhD, Dunham, Jonathan, MD, Tsokos, George C., MD, Luning Prak, Eline T., MD, PhD, Notarangelo, Luigi D., MD

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Familial Immune Thrombocytopenia Associated With a Novel Variant in IKZF1 by Sriaroon, Panida, Chang, Yenhui, Ujhazi, Boglarka, Csomos, Krisztian, Joshi, Hemant R, Zhou, Qin, Close, Devin W, Walter, Jolan E, Kumánovics, Attila

“…We report a novel variant in associated with IKAROS haploinsufficiency in a patient with familial immune thrombocytopenia (ITP). IKAROS, encoded by the gene,…”
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Phage display selection of efficient glutamine‐donor substrate peptides for transglutaminase 2 by Keresztessy, Zsolt, Csősz, Éva, Hársfalvi, Jolán, Csomós, Krisztián, Gray, Joe, Lightowlers, Robert N., Lakey, Jeremy H., Balajthy, Zoltán, Fésüs, László

“…Understanding substrate specificity and identification of natural targets of transglutaminase 2 (TG2), the ubiquitous multifunctional cross‐linking enzyme,…”
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Arthritis in Two Patients With Partial Recombination Activating Gene Deficiency by Wu, Kevin Y, Purswani, Pooja, Ujhazi, Boglarka, Csomos, Krisztian, Snezhina, Mihailova, Elissaveta, Naumova, Stefanov, Stefan, Sharapova, Svetlana, Ellison, Maryssa, Milojevic, Diana, Savic, Sinisa, Sargur, Ravishankar, Walter, Jolan E

“…Autoimmunity is becoming an increasingly recognized complication in patients with primary immunodeficiencies (PIDs), including a variety of combined immune…”
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An Atypical Severe Combined Immunodeficiency (SCID) Case Diagnosis Complicated by Alternative Care in the Era of Newborn Screening (NBS) for SCID by Alberdi, Taylor, MD, Castro-Wagner, Johana B., MD, Patel, Bhumika, MD, Joychan, Sonia, MD, Lindsey, David, MD, Laham, Frederico R., MD, MS, Csomos, Krisztian, PhD, Ujhazi, Boglarka, Duff, Carla M., CPNP, MSN, Trotter, Jessica, MA, BS, CCRP, CRA, Bleesing, Jack J., MD, PhD, Kumanovics, Attila, MD, Chang, Yenhui, MD PhD, Hale, Jamie H, Sriaroon, Panida, MD, FAAAAI, Hale, Greg, MD, Oshrine, Benjamin R., MD, Notarangelo, Luigi, MD, Abraham, Roshini S., PhD, FAAAAI, Comeau, Anne Marie, Petrovic, Aleksandra, MD, Leiding, Jennifer W., MD, FAAAAI, Walter, Jolan E., MD, PhD

“…Results A Florida (FL)-born infant from a midwife-attended home birth was referred for a specialist immunology consultation at 9 months of age after recurrent…”
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