Search Results - "Csoboz, Balint"
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Heat-Shock Proteins in Neuroinflammation
Published in Frontiers in pharmacology (27-08-2019)“…The heat-shock response, one of the main pro-survival mechanisms of a living organism, has evolved as the biochemical response of cells to cope with heat…”
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Merkel cell polyomavirus and non‐Merkel cell carcinomas: guilty or circumstantial evidence?
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-02-2020)“…Merkel cell polyomavirus (MCPyV) is the major causative factor of the rare but aggressive cancer, Merkel cell carcinoma (MCC). Two characteristics of…”
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The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes
Published in International journal of molecular sciences (30-06-2022)“…Small heat shock proteins (sHSPs) have been demonstrated to interact with lipids and modulate the physical state of membranes across species. Through these…”
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Chemotherapy induced PRL3 expression promotes cancer growth via plasma membrane remodeling and specific alterations of caveolae-associated signaling
Published in Cell communication and signaling (29-08-2018)“…The outcome of cancer therapy is greatly defined by the ability of a tumor cell to evade treatment and re-establish its bulk mass after medical interventions…”
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Modulation of Plasma Membrane Composition and Microdomain Organization Impairs Heat Shock Protein Expression in B16-F10 Mouse Melanoma Cells
Published in Cells (Basel, Switzerland) (12-04-2020)“…The heat shock response (HSR) regulates induction of stress/heat shock proteins (HSPs) to preserve proteostasis during cellular stress. Earlier, our group…”
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Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells
Published in Journal of nanobiotechnology (22-01-2019)“…Development of multidrug resistance (MDR) is a major burden of successful chemotherapy, therefore, novel approaches to defeat MDR are imperative. Although the…”
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Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury
Published in Journal of neuroinflammation (10-01-2021)“…Heat-shock protein B1 (HSPB1) is among the most well-known and versatile member of the evolutionarily conserved family of small heat-shock proteins. It has…”
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Plasma membranes as heat stress sensors: From lipid-controlled molecular switches to therapeutic applications
Published in Biochimica et biophysica acta (01-06-2014)“…The classic heat shock (stress) response (HSR) was originally attributed to protein denaturation. However, heat shock protein (Hsp) induction occurs in many…”
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Membrane fluidity matters: hyperthermia from the aspects of lipids and membranes
Published in International journal of hyperthermia (01-08-2013)“…Hyperthermia is a promising treatment modality for cancer in combination both with radio- and chemotherapy. In spite of its great therapeutic potential, the…”
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