Search Results - "Csipő, Tamás"

The Semmelweis Study: a longitudinal occupational cohort study within the framework of the Semmelweis Caring University Model Program for supporting healthy aging by Ungvari, Zoltan, Tabák, Adam G., Adany, Roza, Purebl, György, Kaposvári, Csilla, Fazekas-Pongor, Vince, Csípő, Tamás, Szarvas, Zsófia, Horváth, Krisztián, Mukli, Peter, Balog, Piroska, Bodizs, Robert, Ujma, Peter, Stauder, Adrienne, Belsky, Daniel W., Kovács, Illés, Yabluchanskiy, Andriy, Maier, Andrea B., Moizs, Mariann, Östlin, Piroska, Yon, Yongjie, Varga, Péter, Vokó, Zoltán, Papp, Magor, Takács, István, Vásárhelyi, Barna, Torzsa, Péter, Ferdinandy, Péter, Csiszar, Anna, Benyó, Zoltán, Szabó, Attila J., Dörnyei, Gabriella, Kivimäki, Mika, Kellermayer, Miklos, Merkely, Bela

“…The Semmelweis Study is a prospective occupational cohort study that seeks to enroll all employees of Semmelweis University (Budapest, Hungary) aged 25 years…”
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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses by Csipo, Tamas, Lipecz, Agnes, Owens, Cameron, Mukli, Peter, Perry, Jonathan W., Tarantini, Stefano, Balasubramanian, Priya, Nyúl-Tóth, Ádám, Yabluchanska, Valeriya, Sorond, Farzaneh A., Kellawan, J. Mikhail, Purebl, György, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan, Yabluchanskiy, Andriy

“…Sleep deprivation (SD) is a common condition and an important health concern. In addition to metabolic and cardiovascular risks, SD associates with decreases…”
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Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment by Fulop, Gabor A, Tarantini, Stefano, Yabluchanskiy, Andriy, Molnar, Andrea, Prodan, Calin I, Kiss, Tamas, Csipo, Tamas, Lipecz, Agnes, Balasubramanian, Priya, Farkas, Eszter, Toth, Peter, Sorond, Farzaneh, Csiszar, Anna, Ungvari, Zoltan

“…There has been an increasing appreciation of the role of vascular contributions to cognitive impairment and dementia (VCID) associated with old age. Strong…”
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Improving Cognitive Function with Nutritional Supplements in Aging: A Comprehensive Narrative Review of Clinical Studies Investigating the Effects of Vitamins, Minerals, Antioxidants, and Other Dietary Supplements by Fekete, Mónika, Lehoczki, Andrea, Tarantini, Stefano, Fazekas-Pongor, Vince, Csípő, Tamás, Csizmadia, Zoltán, Varga, János Tamás

“…Cognitive impairment and dementia are burgeoning public health concerns, especially given the increasing longevity of the global population. These conditions…”
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Exploring the Influence of Gut-Brain Axis Modulation on Cognitive Health: A Comprehensive Review of Prebiotics, Probiotics, and Symbiotics by Fekete, Mónika, Lehoczki, Andrea, Major, Dávid, Fazekas-Pongor, Vince, Csípő, Tamás, Tarantini, Stefano, Csizmadia, Zoltán, Varga, János Tamás

“…Recent research exploring the relationship between the gut and the brain suggests that the condition of the gut microbiota can influence cognitive health. A…”
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The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD-A Review by Fekete, Mónika, Csípő, Tamás, Fazekas-Pongor, Vince, Fehér, Ágnes, Szarvas, Zsófia, Kaposvári, Csilla, Horváth, Krisztián, Lehoczki, Andrea, Tarantini, Stefano, Varga, János Tamás

“…Currently, an increasing amount of evidence supports the notion that vitamins C, D and E, carotenoids, and omega-3 fatty acids may protect against the…”
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The Possible Role of Food and Diet in the Quality of Life in Patients with COPD-A State-of-the-Art Review by Fekete, Mónika, Csípő, Tamás, Fazekas-Pongor, Vince, Bálint, Madarász, Csizmadia, Zoltán, Tarantini, Stefano, Varga, János Tamás

“…Diet has been described as a modifiable risk factor for the development and progression of chronic diseases, and emerging evidence increasingly points to its…”
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Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults by Csipo, Tamas, Lipecz, Agnes, Mukli, Peter, Bahadli, Dhay, Abdulhussein, Osamah, Owens, Cameron D, Tarantini, Stefano, Hand, Rachel A, Yabluchanska, Valeriya, Kellawan, J Mikhail, Sorond, Farzaneh, James, Judith A, Csiszar, Anna, Ungvari, Zoltan I, Yabluchanskiy, Andriy

“…Understanding how the brain allocates resources to match the demands of active neurons under physiological conditions is critically important. Increased…”
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Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects by Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wren, Jonathan D., Garman, Lori, Csiszar, Anna, Ungvari, Zoltan

“…Aging-induced structural and functional alterations of the neurovascular unit lead to impairment of neurovascular coupling responses, dysregulation of cerebral…”
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain by Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, DelFavero, Jordan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wiley, Graham, Garman, Lori, Csiszar, Anna, Ungvari, Zoltan

“…Age-related phenotypic changes of cerebromicrovascular endothelial cells lead to dysregulation of cerebral blood flow and blood-brain barrier disruption,…”
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Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases by Fekete, Monika, Szarvas, Zsofia, Fazekas-Pongor, Vince, Feher, Agnes, Csipo, Tamas, Forrai, Judit, Dosa, Norbert, Peterfi, Anna, Lehoczki, Andrea, Tarantini, Stefano, Varga, Janos Tamas

“…An increasing number of studies suggest that diet plays an important role in regulating aging processes and modulates the development of the most important…”
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A Central Role for TRPM4 in Ca2+-Signal Amplification and Vasoconstriction by Csípő, Tamás, Czikora, Ágnes, Fülöp, Gábor Á., Gulyás, Hajnalka, Rutkai, Ibolya, Tóth, Enikő Pásztorné, Pórszász, Róbert, Szalai, Andrea, Bölcskei, Kata, Helyes, Zsuzsanna, Pintér, Erika, Papp, Zoltán, Ungvári, Zoltán, Tóth, Attila

“…Transient receptor potential melastatin-4 (TRPM4) is activated by an increase in intracellular Ca2+ concentration and is expressed on smooth muscle cells…”
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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood by Kiss, Tamas, Tarantini, Stefano, Csipo, Tamas, Balasubramanian, Priya, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Wren, Jonathan D., Garman, Lori, Huffman, Derek M., Csiszar, Anna, Ungvari, Zoltan

“…Aging-induced functional and phenotypic alterations of the vasculature (e.g., endothelial dysfunction, oxidative stress) have a central role in morbidity and…”
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Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases by Ungvari, Zoltan, Tarantini, Stefano, Nyúl-Tóth, Ádám, Kiss, Tamas, Yabluchanskiy, Andriy, Csipo, Tamas, Balasubramanian, Priya, Lipecz, Agnes, Benyo, Zoltan, Csiszar, Anna

“…Aging is associated with increased oxidative stress in vascular endothelial and smooth muscle cells, which contribute to the development of a wide range of…”
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Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice by Tarantini, Stefano, Balasubramanian, Priya, Delfavero, Jordan, Csipo, Tamas, Yabluchanskiy, Andriy, Kiss, Tamas, Nyúl-Tóth, Ádám, Mukli, Peter, Toth, Peter, Ahire, Chetan, Ungvari, Anna, Benyo, Zoltan, Csiszar, Anna, Ungvari, Zoltan

“…Moment-to-moment adjustment of regional cerebral blood flow to neuronal activity via neurovascular coupling (NVC or “functional hyperemia”) has a critical role…”
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Retinal biomarkers for Alzheimer’s disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis by Czakó, Cecilia, Kovács, Tibor, Ungvari, Zoltan, Csiszar, Anna, Yabluchanskiy, Andriy, Conley, Shannon, Csipo, Tamas, Lipecz, Agnes, Horváth, Hajnalka, Sándor, Gábor László, István, Lilla, Logan, Trevor, Nagy, Zoltán Zsolt, Kovács, Illés

“…Cognitive impairment and dementia are major medical, social, and economic public health issues worldwide with significant implications for life quality in…”
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Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation–induced impairment of neurovascular coupling responses protecting cognitive function in mice by Yabluchanskiy, Andriy, Tarantini, Stefano, Balasubramanian, Priya, Kiss, Tamas, Csipo, Tamas, Fülöp, Gábor A., Lipecz, Agnes, Ahire, Chetan, DelFavero, Jordan, Nyul-Toth, Adam, Sonntag, William E., Schwartzman, Michal L., Campisi, Judith, Csiszar, Anna, Ungvari, Zoltan

“…Whole brain irradiation (WBI, also known as whole brain radiation therapy or WBRT) is a mainstream therapy for patients with identifiable brain metastases and…”
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Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment by István, Lilla, Czakó, Cecilia, Élő, Ágnes, Mihály, Zsuzsanna, Sótonyi, Péter, Varga, Andrea, Ungvári, Zoltán, Csiszár, Anna, Yabluchanskiy, Andriy, Conley, Shannon, Csipő, Tamás, Lipecz, Ágnes, Kovács, Illés, Nagy, Zoltán Zsolt

“…Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting the aging populations of the Western world. CAS is frequently…”
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype by Tarantini, Stefano, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Csipo, Tamas, Mukli, Peter, Balasubramanian, Priya, Ungvari, Anna, Toth, Peter, Benyo, Zoltan, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna

“…Age-related impairment of neurovascular coupling (NVC; or “functional hyperemia”) compromises moment-to-moment adjustment of regional cerebral blood flow to…”
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Accelerated ageing and coronary microvascular dysfunction in chronic heart failure in Tgαq44 mice by Berkowicz, Piotr, Totoń-Żurańska, Justyna, Kwiatkowski, Grzegorz, Jasztal, Agnieszka, Csípő, Tamás, Kus, Kamil, Tyrankiewicz, Urszula, Orzyłowska, Anna, Wołkow, Paweł, Tóth, Attila, Chlopicki, Stefan

“…Age represents a major risk factor in heart failure (HF). However, the mechanisms linking ageing and HF are not clear. We aimed to identify the functional,…”
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