Search Results - "Csernok, E"

Utility of serum complement factors C3 and C4 as biomarkers during therapeutic management of giant cell arteritis by Conticini, E, Hellmich, B, Frediani, B, Csernok, E, Löffler, C

“…There is a strong unmet need for biomarkers in giant cell arteritis (GCA), as C-reactive protein (CRP) may be unreliable in patients treated with Tocilizumab…”
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Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis: challenges and solutions 2014 by Schönermarck, Ulf, Csernok, Elena, Gross, Wolfgang L

“…Anti-neutrophil cytoplasmic autoantibodies (ANCA) with specificity for proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are a defining feature of…”
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Proinflammatory Cytokines and Autoimmunity in Churg-Strauss Syndrome by HELLMICH, B., CSERNOK, E., GROSS, W. L.

“…: Churg‐Strauss syndrome (CSS) belongs to the antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitides and is further characterized by severe…”
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ANCA diagnostics in vasculitis by Csernok, E, Hellmich, B

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Eotaxin-3 is involved in Churg–Strauss syndrome – a serum marker closely correlating with disease activity by Polzer, K., Karonitsch, T., Neumann, T., Eger, G., Haberler, C., Soleiman, A., Hellmich, B., Csernok, E., Distler, J., Manger, B., Redlich, K., Schett, G., Zwerina, J.

“…Objective. Churg–Strauss Syndrome (CSS) is characterized by excessive eosinophil accumulation in peripheral blood and affected tissues with development of…”
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Serum HMGB1 levels are increased in active Wegener's granulomatosis and differentiate between active forms of ANCA-associated vasculitis by Wibisono, D, Csernok, E, Lamprecht, P, Holle, J U, Gross, W L, Moosig, F

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Correlation of serum level of high mobility group box 1 with the burden of granulomatous inflammation in granulomatosis with polyangiitis (Wegener's) by Henes, F O, Chen, Y, Bley, T A, Fabel, M, Both, M, Herrmann, K, Csernok, E, Gross, W L, Moosig, F

“…To investigate the correlation of serum levels of high mobility group box 1 (HMGB1) with the extent of granulomatous inflammation in granulomatosis with…”
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A critical evaluation of commercial immunoassays for antineutrophil cytoplasmic antibodies directed against proteinase 3 and myeloperoxidase in Wegener's granulomatosis and microscopic polyangiitis by Csernok, E., Ahlquist, D., Ullrich, S., Gross, W. L.

“…Objective. To evaluate the performance of 11 commercial enzyme‐linked immunosorbent assay (ELISA) kits for the detection of antineutrophil cytoplasmic…”
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Evaluation of capture ELISA for detection of antineutrophil cytoplasmic antibodies directed against proteinase 3 in Wegener's granulomatosis: first results from a multicentre study by Csernok, Elena, Holle, Julia, Hellmich, Bernhard, Willem, Jan, Tervaert, Cohen, Kallenberg, Cees G. M., Limburg, Peter C., Niles, John, Pan, Gouli, Specks, Ulrich, Westman, Kerstin, Wieslander, Jörgen, De Groot, Kirsten, Gross, Wolfgang L.

“…Objective: To evaluate the performance characteristics of direct and capture ELISA for the detection of PR3-ANCA in Wegener's granulomatosis (WG) in…”
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Diagnostic Value of Procalcitonin in ANCA-Associated Vasculitis (AAV) to Differentiate Between Disease Activity, Infection and Drug Hypersensitivity by Herrmann, K, Schinke, S, Csernok, E, Moosig, F, Holle, J U

“…Procalcitonin (PCT) is considered to be a specific marker for severe bacterial infections and sepsis. Elevated PCT levels have been reported in active…”
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Clinical evaluation of hsPR3-ANCA ELISA for detection of antineutrophil cytoplasmatic antibodies directed against proteinase 3 by Holle, J U, Csernok, E, Fredenhagen, G, Backes, M, Bremer, J P, Gross, W L

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Effector memory T cells as driving force of granuloma formation and autoimmunity in Wegener's granulomatosis by Lamprecht, P., Csernok, E., Gross, W. L.

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Are anti-cyclic citrullinated peptide autoantibodies seromarkers for rheumatoid vasculitis in a cohort of patients with systemic vasculitis? by Laskari, K, Laskaria, K, Ahmadi-Simab, K, Lamken, M, Csernok, E, Gross, W L, Hellmich, B

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A novel high sensitivity ELISA for detection of antineutrophil cytoplasm antibodies against proteinase-3 by HELLMICH, B, CSEMOK, E, FREDENHAGEN, G, GROSS, W. L

“…Conventional direct enzyme-linked immunosorbent assays (ELISA) for the detection of anti-neutrophil cytoplasm antibodies (ANCA) often lack sensitivity because…”
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CD28 negative T cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis by Lamprecht, P, Moosig, F, Csernok, E, Seitzer, U, Schnabel, A, Mueller, A, Gross, W L

“…BACKGROUND Lack of CD28 expression on peripheral blood CD4+ and CD8+ T cells has been reported in patients with Wegener's granulomatosis (WG), suggesting a…”
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Small vessel vasculitis and relapsing panniculitis in tumour necrosis factor receptor associated periodic syndrome (TRAPS) by Lamprecht, P, Moosig, F, Adam-Klages, S, Mrowietz, U, Csernok, E, Kirrstetter, M, Ahmadi-Simab, K, Schroder, J O, Gross, W L

“…Case reports: A 66 year old female patient had relapsing fever and non-suppurative panniculitis suggestive of enigmatic “Weber-Christian disease” (WCD)…”
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Evaluation of the FIDIS Vasculitis Multiplex Immunoassay for Diagnosis and Follow-up of ANCA-Associated Vasculitis and Goodpasture's Disease by DAMOISEAUX, J., VAESSEN, M., KNAPEN, Y., CSERNOK, E., STEGEMAN, C. A., VAN PAASSEN, P., COHEN TERVAERT, J. W.

“…:  We have evaluated a new‐multiplex immunoassay (FIDIS Vasculitis) for simultaneous detection and quantification of anti‐MPO, ‐PR3, and ‐glomerular basement…”
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Proteinase 3, protease-activated receptor-2 and interleukin-32 : linking innate and autoimmunity in Wegener's granulomatosis by CSERNOK, E, HOLLE, J. U, GROSS, W. L

“…Proteinase 3 (PR3) is a multifunctional neutrophil-derived serine protease influencing cell cycle, differentiation, and cell death. This molecule is the main…”
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Paradigm shift in ANCA diagnostics : New international consensus recommendations by Csernok, E, Kempiners, N, Hellmich, B

“…Up to now indirect immunofluorescence (IIF) followed by an antigen-specific assay specific for proteinase 3 (PR3) or myeloperoxidase (MPO) has been the…”
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Prevalence and spectrum of rheumatic diseases associated with proteinase 3‐antineutrophil cytoplasmic antibodies (ANCA) and myeloperoxidase‐ANCA by Schönermarck, U., Lamprecht, P., Csernok, E., Gross, W. L.

“…Objectives. To evaluate the prevalence and association of antineutrophil cytoplasmic antibodies (ANCA) and their subtypes [proteinase 3 (PR3)‐ANCA,…”
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