Increased frequency of thyroid nodules and breast fibroadenomas in women with uterine fibroids

Increased frequency of thyroid nodules and breast fibroadenomas in women with uterine fibroids

Fibroids or leiomyomas or myomas of the uterus are the most common benign gynecologic disease, while fibroadenomas of the breast are most frequently seen in young women, usually within 20 years after puberty. Multiple tumors in one or both breasts are found in 10-15% of patients. Single thyroid nodu...

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Bibliographic Details
Published in:Thyroid (New York, N.Y.) Vol. 17; no. 12; p. 1257
Main Authors: Spinos, Nikitas, Terzis, George, Crysanthopoulou, Athina, Adonakis, George, Markou, Kostas B, Vervita, Vasiliki, Koukouras, Dimitrios, Tsapanos, Vasilios, Decavalas, George, Kourounis, George, Georgopoulos, Neoklis A
Format: Journal Article
Language:English
Published: United States 01-12-2007
Subjects:
Adult
Breast Neoplasms - complications
Breast Neoplasms - diagnosis
Case-Control Studies
Cross-Sectional Studies
Female
Fibroadenoma - complications
Fibroadenoma - diagnosis
Humans
Incidence
Leiomyoma - complications
Leiomyoma - diagnosis
Middle Aged
Risk Factors
Thyroid Nodule - complications
Thyroid Nodule - diagnosis
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Summary:Fibroids or leiomyomas or myomas of the uterus are the most common benign gynecologic disease, while fibroadenomas of the breast are most frequently seen in young women, usually within 20 years after puberty. Multiple tumors in one or both breasts are found in 10-15% of patients. Single thyroid nodules are much more common in women than in men, and their prevalence increases with age. The aim of the present study was to determine cross-sectionally the incidence of solitary thyroid nodules and fibroadenomas of the breast in women with uterine fibroids. In women with uterine adenomas, the frequency of fibroadenomas of the breast was 65% and of thyroid nodules was 38.7%, while in women with a normal uterus, the frequency was 35% and 20%, respectively. Therefore, women with uterine fibroids have an increased incidence of thyroid nodules (t = 4.68, p = 0.030) and of fibroadenomas of the breast (t = 11.74, p = 0.001).
ISSN:1050-7256
DOI:10.1089/thy.2006.0330