Search Results - "Cryan, John F"
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The Microbiota-Gut-Brain Axis: From Motility to Mood
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2021)“…The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and extrinsic factors influence signaling along this axis, modulating the…”
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Gut Microbe to Brain Signaling: What Happens in Vagus
Published in Neuron (Cambridge, Mass.) (20-03-2019)“…The gut microbiota has emerged as a key player in health and disease. Here we discuss the vagus nerve, which connects the visceral organs and the brain, as an…”
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The Microbiome-Gut-Brain Axis in Health and Disease
Published in Gastroenterology clinics of North America (01-03-2017)“…Gut microbes are capable of producing most neurotransmitters found in the human brain. Evidence is accumulating to support the view that gut microbes influence…”
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The gut microbiome in neurological disorders
Published in Lancet neurology (01-02-2020)“…Research into the role of the gut microbiome in modulating brain function has rapidly increased over the past 10 years, albeit chiefly in animal models…”
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Brain-Gut-Microbiota Axis and Mental Health
Published in Psychosomatic medicine (01-10-2017)“…The brain-gut-microbiota axis has been put forward as a new paradigm in neuroscience, which may be of relevance to mental illness. The mechanisms of signal…”
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Anxiety, Depression, and the Microbiome: A Role for Gut Peptides
Published in Neurotherapeutics (01-01-2018)“…The complex bidirectional communication between the gut and the brain is finely orchestrated by different systems, including the endocrine, immune, autonomic,…”
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Using the rat forced swim test to assess antidepressant-like activity in rodents
Published in Nature protocols (01-06-2012)“…The forced swim test (FST) is one of the most commonly used animal models for assessing antidepressant-like behavior. This protocol details using the FST in…”
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Psychobiotics: A Novel Class of Psychotropic
Published in Biological psychiatry (1969) (15-11-2013)“…Here, we define a psychobiotic as a live organism that, when ingested in adequate amounts, produces a health benefit in patients suffering from psychiatric…”
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John F. Cryan
Published in Neuron (Cambridge, Mass.) (01-11-2023)“…John Cryan focuses his research on the intersection of the brain, gut, and microbiome. He discusses with Neuron the growing acceptance among neuroscientists…”
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Recent developments in understanding the role of the gut microbiota in brain health and disease
Published in Annals of the New York Academy of Sciences (01-05-2018)“…There is a growing appreciation of the role of the gut microbiota in all aspects of health and disease, including brain health. Indeed, roles for the bacterial…”
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Microbiota and the social brain
Published in Science (American Association for the Advancement of Science) (01-11-2019)“…Sociability can facilitate mutually beneficial outcomes such as division of labor, cooperative care, and increased immunity, but sociability can also promote…”
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Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology
Published in Psychoneuroendocrinology (01-09-2012)“…Summary There is now an expanding volume of evidence to support the view that commensal organisms within the gut play a role in early programming and later…”
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Stress & the gut-brain axis: Regulation by the microbiome
Published in Neurobiology of stress (01-12-2017)“…The importance of the gut-brain axis in regulating stress-related responses has long been appreciated. More recently, the microbiota has emerged as a key…”
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Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system
Published in Developmental biology (15-09-2016)“…The enteric nervous system (ENS), considered a separate branch of the autonomic nervous system, is located throughout the length of the gastrointestinal (GI)…”
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Gut microbes and the brain: paradigm shift in neuroscience
Published in The Journal of neuroscience (12-11-2014)“…The discovery of the size and complexity of the human microbiome has resulted in an ongoing reevaluation of many concepts of health and disease, including…”
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The blood-brain barrier in aging and neurodegeneration
Published in Molecular psychiatry (01-06-2022)“…The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an exquisite control of exchange of compounds between the blood and the…”
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Microbiota-Gut-Brain Axis: Modulator of Host Metabolism and Appetite
Published in The Journal of nutrition (01-05-2017)“…The gut harbors an enormous diversity of microbes that are essential for the maintenance of homeostasis in health and disease. A growing body of evidence…”
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Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice
Published in Biological psychiatry (1969) (01-10-2017)“…Abstract Background The realization that the microbiota-gut-brain axis plays a critical role in health and disease, including neuropsychiatric disorders, is…”
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Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals
Published in Trends in neurosciences (Regular ed.) (01-11-2016)“…Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested, confer mental health benefits through interactions with commensal gut…”
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Microbiota-Gut-Brain Axis: New Therapeutic Opportunities
Published in Annual review of pharmacology and toxicology (06-01-2020)“…The traditional fields of pharmacology and toxicology are beginning to consider the substantial impact our gut microbiota has on host physiology. The…”
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