Search Results - "Cruzado, J. M"

Subclinical Rejection Associated with Chronic Allograft Nephropathy in Protocol Biopsies as a Risk Factor for Late Graft Loss by Moreso, F., Ibernon, M., Gomà, M., Carrera, M., Fulladosa, X., Hueso, M., Gil‐Vernet, S., Cruzado, J. M., Torras, J., Grinyó, J. M., Serón, D.

“…Chronic allograft nephropathy (CAN) in protocol biopsies is associated with graft loss while the association between subclinical rejection (SCR) and outcome…”
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Pretransplant Immediately Early‐1‐Specific T Cell Responses Provide Protection for CMV Infection After Kidney Transplantation by Bestard, O., Lucia, M., Crespo, E., Van Liempt, B., Palacio, D., Melilli, E., Torras, J., Llaudó, I., Cerezo, G., Taco, O., Gil‐Vernet, S., Grinyó, J. M., Cruzado, J. M.

“…Cytomegalovirus (CMV) infection is still a major complication after kidney transplantation. Although cytotoxic CMV‐specific T cells play a crucial role…”
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Contribution of Population Pharmacokinetics to Dose Optimization of Ganciclovir-Valganciclovir in Solid-Organ Transplant Patients by Padullés, A, Colom, H, Bestard, O, Melilli, E, Sabé, N, Rigo, R, Niubó, J, Torras, J, Lladó, L, Manito, N, Caldés, A, Cruzado, J M, Grinyó, J M, Lloberas, N

“…Treatment of solid-organ transplant (SOT) patients with ganciclovir (GCV)-valganciclovir (VGCV) according to the manufacturer's recommendations may result in…”
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Hepatocyte growth factor gene therapy enhances infiltration of macrophages and may induce kidney repair in db/db mice as a model of diabetes by Flaquer, M., Franquesa, M., Vidal, A., Bolaños, N., Torras, J., Lloberas, N., Herrero-Fresneda, I., Grinyó, J. M., Cruzado, J. M.

“…Aims/hypothesis We previously demonstrated hepatocyte growth factor (HGF) gene therapy was able to induce regression of glomerulosclerosis in diabetic…”
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Cross‐Validation of IFN‐γ Elispot Assay for Measuring Alloreactive Memory/Effector T Cell Responses in Renal Transplant Recipients by Bestard, O., Crespo, E., Stein, M., Lúcia, M., Roelen, D. L., de Vaal, Y. J., Hernandez‐Fuentes, M. P., Chatenoud, L., Wood, K. J., Claas, F. H., Cruzado, J. M., Grinyó, J. M., Volk, H. D., Reinke, P.

“…Assessment of donor‐specific alloreactive memory/effector T cell responses using an IFN‐γ Elispot assay has been suggested to be a novel immune‐monitoring tool…”
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Intragraft Regulatory T Cells in Protocol Biopsies Retain Foxp3 Demethylation and Are Protective Biomarkers for Kidney Graft Outcome by Bestard, O., Cuñetti, L., Cruzado, J. M., Lucia, M., Valdez, R., Olek, S., Melilli, E., Torras, J., Mast, R., Gomà, M., Franquesa, M., Grinyó, J. M.

“…Presence of subclinical rejection (SCR) with IF/TA in protocol biopsies of renal allografts has been shown to be an independent predictor factor of graft loss…”
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Long‐Term Results of Biopsy‐Guided Selection and Allocation of Kidneys From Older Donors in Older Recipients by Fernández‐Lorente, L., Riera, L., Bestard, O., Carrera, M., Gomà, M., Porta, N., Torras, J., Melilli, E., Gil‐Vernet, S., Grinyó, J. M., Cruzado, J. M.

“…In our old‐for‐old program, we discard or allocate older extended criteria donor kidneys to single (SKT) or dual kidney transplantation (DKT) depending on…”
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Clinical Features and Outcomes of Tuberculosis in Solid Organ Transplant Recipients by Bodro, M, Sabé, N, Santín, M, Cruzado, J.M, Lladó, L, González-Costello, J, Carratalà, J

“…Abstract Background Tuberculosis (TB) remains a significant opportunistic infection in solid organ transplant (SOT) recipients. Moreover, its optimal treatment…”
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Successful Treatment of Chronic HCV Infection Should Not Preclude Kidney Donation to an HCV Negative Recipient by Cruzado, J. M., Gil‐Vernet, S., Castellote, J., Bestard, O., Melilli, E., Grinyó, J. M.

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Association of ANRIL gene polymorphisms with major adverse cardiovascular events in hemodialysis patients by Arbiol-Roca, A, Padró-Miquel, A, Hueso, M, Navarro, E, Alía-Ramos, P, González-Álvarez, MT, Rama, I, Torras, J, Grinyó, JM, Cruzado, JM, Lloberas, N

“…Cardiovascular disease is the leading cause of death in patients with chronic kidney disease (CKD). Single nucleotide polymorphisms (SNPs) in ANRIL gene have…”
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In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection by Ripoll, E, Pluvinet, R, Torras, J, Olivar, R, Vidal, A, Franquesa, M, Cassis, L, Cruzado, J M, Bestard, O, Grinyó, J M, Aran, J M, Herrero-Fresneda, I

“…The humoral branch of the immune response has an important role in acute and chronic allograft dysfunction. The CD40/CD40L costimulatory pathway is crucial in…”
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Mycophenolate Mofetil and Sirolimus Combination in Renal Transplantation by Grinyó, J. M., Cruzado, J. M.

“…Mycophenolate mofetil (MMF) and sirolimus (SRL) are potent non‐nephrotoxic xenobiotic immunosuppressants. Their complementary properties may provide the…”
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Successful outcome of ganciclovir-resistant cytomegalovirus infection in organ transplant recipients after conversion to mTOR inhibitors by Sabé, N, González-Costello, J, Rama, I, Niubó, J, Bodro, M, Roca, J, Cruzado, J M, Manito, N, Carratalà, J

“…Ganciclovir-resistant (GanR) cytomegalovirus (CMV) infection after organ transplantation is emerging as a significant therapeutic challenge. We report two…”
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Sterile Leukocyturia Is Associated With Interstitial Fibrosis and Tubular Atrophy in Kidney Allograft Protocol Biopsies by Coelho, S., Ortíz, F., Gelpi, R., Koskinen, P., Porta, N., Bestard, O., Melilli, E., Taco, O., Torras, J., Honkanen, E., Grinyó, J. M., Cruzado, J. M.

“…Kidney allograft interstitial fibrosis and tubular atrophy (IF/TA) is associated with a poorer renal function and outcome. In the current clinical practice, an…”
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Revisiting Double Kidney Transplantation: Two Kidneys Provide Better Graft Survival Than One by Cruzado, J.M, Fernandez, L, Riera, L, Bestard, O, Carrera, M, Torras, J, Vernet, S. Gil, Melilli, E, Ngango, L, Grinyó, J.M

“…Abstract Double kidney transplantation is an accepted strategy to increase the donor pool. Regarding older donor kidneys, protocols for deciding to perform a…”
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Immunephenotype of Glomerular and Interstitial Infiltrating Cells in Protocol Renal Allograft Biopsies and Histological Diagnosis by Moreso, F., Seron, D., O'Valle, F., Ibernon, M., Gomà, M., Hueso, M., Cruzado, J. M., Bestard, O., Duarte, V., García del Moral, R., Grinyó, J. M.

“…Patients with a protocol renal allograft biopsy simultaneously displaying interstitial fibrosis/tubular atrophy (IF/TA) and subclinical rejection (SCR) have a…”
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Successful Renal Transplantation in a Patient with Atypical Hemolytic Uremic Syndrome Carrying Mutations in Both Factor I and MCP by Cruzado, J. M., De Córdoba, S. Rodríguez, Melilli, E., Bestard, O., Rama, I., Sánchez‐Corral, P., López‐Trascasa, M., Navarro, I., Torras, J., Gomà, M., Grinyó, J. M.

“…Kidney transplantation in patients with atypical hemolytic uremic syndrome (aHUS) carrying mutations in the soluble complement regulators factor H (CFH) or…”
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Therapy With Plasmapheresis and Intravenous Immunoglobulin for Acute Humoral Rejection in Kidney Transplantation by Ibernón, M., Gil-Vernet, S., Carrera, M., Serón, D., Moreso, F., Bestard, O., Cruzado, J.M., Grinyó, J.M.

“…Acute humoral rejection (AHR) is characterized by acute graft dysfunction associated with de novo production of donor-specific alloantibodies (DSA) and C4d…”
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Direct electrotransfer of hHGF gene into kidney ameliorates ischemic acute renal failure by FRANQUESA, M, ALPEROVICH, G, HERRERO-FRESNEDA, I, LLOBERAS, N, BOLANOS, N, FILLAT, C, RAMA, I, CRUZADO, J. M, GRINYO, J. M, TORRAS, J

“…In the early phase of kidney transplantation, the transplanted kidney is exposed to insults like ischemia/reperfusion, which is a leading cause of acute renal…”
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New immunosuppresor strategies in the treatment of murine lupus nephritis by Alperovich, G, Rama, I, Lloberas, N, Franquesa, M, Poveda, R, Gomà, M, Herrero-Fresneda, I, Cruzado, J M, Bolaños, N, Carrera, M, Grinyó, J M, Torras, J

“…Renal involvement in systemic lupus erythematosus is a common complication that significantly worsens morbidity and mortality. Although treatment with…”
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