Search Results - "Cruz Hernández, Jean C."

In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain by Ouzounov, Dimitre G, Wang, Tianyu, Wang, Mengran, Feng, Danielle D, Horton, Nicholas G, Cruz-Hernández, Jean C, Cheng, Yu-Ting, Reimer, Jacob, Tolias, Andreas S, Nishimura, Nozomi, Xu, Chris

“…Ouzounov et al . report calcium imaging with three-photon microscopy in the mouse brain. The approach enabled noninvasive recording of activity with high…”
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Causes and consequences of baseline cerebral blood flow reductions in Alzheimer’s disease by Bracko, Oliver, Cruz Hernández, Jean C, Park, Laibaik, Nishimura, Nozomi, Schaffer, Chris B

“…Reductions of baseline cerebral blood flow (CBF) of ∼10–20% are a common symptom of Alzheimer’s disease (AD) that appear early in disease progression and…”
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Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models by Cruz Hernández, Jean C., Bracko, Oliver, Kersbergen, Calvin J., Muse, Victorine, Haft-Javaherian, Mohammad, Berg, Maxime, Park, Laibaik, Vinarcsik, Lindsay K., Ivasyk, Iryna, Rivera, Daniel A., Kang, Yiming, Cortes-Canteli, Marta, Peyrounette, Myriam, Doyeux, Vincent, Smith, Amy, Zhou, Joan, Otte, Gabriel, Beverly, Jeffrey D., Davenport, Elizabeth, Davit, Yohan, Lin, Charles P., Strickland, Sidney, Iadecola, Costantino, Lorthois, Sylvie, Nishimura, Nozomi, Schaffer, Chris B.

“…Cerebral blood flow (CBF) reductions in Alzheimer’s disease patients and related mouse models have been recognized for decades, but the underlying mechanisms…”
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High fat diet worsens Alzheimer’s disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow by Bracko, Oliver, Vinarcsik, Lindsay K., Cruz Hernández, Jean C., Ruiz-Uribe, Nancy E., Haft-Javaherian, Mohammad, Falkenhain, Kaja, Ramanauskaite, Egle M., Ali, Muhammad, Mohapatra, Aditi, Swallow, Madisen A., Njiru, Brendah N., Muse, Victorine, Michelucci, Pietro E., Nishimura, Nozomi, Schaffer, Chris B.

“…Obesity is linked to increased risk for and severity of Alzheimer’s disease (AD). Cerebral blood flow (CBF) reductions are an early feature of AD and are also…”
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Use of Tethered Enzymes as a Platform Technology for Rapid Analyte Detection by Cohen, Roy, Lata, James P, Lee, Yurim, Hernández, Jean C Cruz, Nishimura, Nozomi, Schaffer, Chris B, Mukai, Chinatsu, Nelson, Jacquelyn L, Brangman, Sharon A, Agrawal, Yash, Travis, Alexander J

“…Rapid diagnosis for time-sensitive illnesses such as stroke, cardiac arrest, and septic shock is essential for successful treatment. Much attention has…”
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Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis by Pulous, Fadi E., Cruz-Hernández, Jean C., Yang, Chongbo, Kaya, Ζeynep, Paccalet, Alexandre, Wojtkiewicz, Gregory, Capen, Diane, Brown, Dennis, Wu, Juwell W., Schloss, Maximilian J., Vinegoni, Claudio, Richter, Dmitry, Yamazoe, Masahiro, Hulsmans, Maarten, Momin, Noor, Grune, Jana, Rohde, David, McAlpine, Cameron S., Panizzi, Peter, Weissleder, Ralph, Kim, Dong-Eog, Swirski, Filip K., Lin, Charles P., Moskowitz, Michael A., Nahrendorf, Matthias

“…Interactions between the immune and central nervous systems strongly influence brain health. Although the blood–brain barrier restricts this crosstalk, we now…”
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Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations by Zhou, Xiaolai, Sun, Lirong, Bracko, Oliver, Choi, Ji Whae, Jia, Yan, Nana, Alissa L., Brady, Owen Adam, Hernandez, Jean C. Cruz, Nishimura, Nozomi, Seeley, William W., Hu, Fenghua

“…Haploinsufficiency of progranulin (PGRN) due to mutations in the granulin ( GRN ) gene causes frontotemporal lobar degeneration (FTLD), and complete loss of…”
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STALLED BLOOD FLOW IN BRAIN CAPILLARIES IS RESPONSIBLE FOR REDUCED CORTICAL PERFUSION IN A MOUSE MODEL OF ALZHEIMER’S DISEASE by Cruz Hernandez, Jean C, Kersbergen, Calvin, Muse, Victorine, Ivasyk, Iryna, Bracko, Oliver, Haft-Javaherian, Mohammad, Kang, Yiming, Zhou, Joan, Beverly, Jeffrey D, Slack, Elizabeth, Otte, Gabriel, Santisakultarm, Thom P, Iadecola, Costantino, Nishimura, Nozomi, Schaffer, Chris B

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HIGH FAT DIET EXACERBATES CAPILLARY STALLING AND ALZHEIMER'S DISEASE-RELATED PATHOLOGY IN THE APP/PS1 MOUSE MODEL by Bracko, Oliver, Cruz Hernandez, Jean C., Vinarcsik, Lindsay K., Ali, Muhammad, Swallow, Madison, Zheng, Jieyu, Njiru, Brendah N., Nishimura, Nozomi, Schaffer, Chris B.

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P2‐212: HIGH FAT DIET EXACERBATES CAPILLARY STALLING AND ALZHEIMER'S DISEASE‐RELATED PATHOLOGY IN THE APP/PS1 MOUSE MODEL by Bracko, Oliver, Cruz Hernandez, Jean C., Vinarcsik, Lindsay K., Ali, Muhammad, Swallow, Madison, Zheng, Jieyu, Njiru, Brendah N., Nishimura, Nozomi, Schaffer, Chris B.

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STALLED BLOOD FLOW IN BRAIN CAPILLARIES IS RESPONSIBLE FOR REDUCED CORTICAL PERFUSION AND IMPACTS COGNITIVE FUNCTION IN MOUSE MODELS OF ALZHEIMER’S DISEASE by Bracko, Oliver, Cruz Hernandez, Jean C., Njiru, Brendah N., Swallow, Madison, Zheng, Jieyu, Ali, Muhammad, Kersbergen, Calvin, Muse, Victorine, Haft-Javaherian, Mohammad, Park, Laibaik, Vinarcsik, Lindsay K., Ivasyk, Iryna, Kang, Yiming, Zhou, Joan, Otte, Gabriel, Beverly, Jeffrey D., Slack, Elizabeth, Iadecola, Costantino, Nishimura, Nozomi, Schaffer, Chris B.

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O2‐12‐04: STALLED BLOOD FLOW IN BRAIN CAPILLARIES IS RESPONSIBLE FOR REDUCED CORTICAL PERFUSION AND IMPACTS COGNITIVE FUNCTION IN MOUSE MODELS OF ALZHEIMER'S DISEASE by Bracko, Oliver, Cruz Hernandez, Jean C., Njiru, Brendah N., Swallow, Madison, Zheng, Jieyu, Ali, Muhammad, Kersbergen, Calvin, Muse, Victorine, Haft-Javaherian, Mohammad, Park, Laibaik, Vinarcsik, Lindsay K., Ivasyk, Iryna, Kang, Yiming, Zhou, Joan, Otte, Gabriel, Beverly, Jeffrey D., Slack, Elizabeth, Iadecola, Costantino, Nishimura, Nozomi, Schaffer, Chris B.

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P4‐097: Stalled Blood flow in Brain Capillaries is Responsible for Reduced Cortical Perfusion in a Mouse Model of Alzheimer’s Disease by Cruz Hernandez, Jean C., Kersbergen, Calvin, Muse, Victorine, Ivasyk, Iryna, Bracko, Oliver, Haft-Javaherian, Mohammad, Kang, Yiming, Zhou, Joan, Beverly, Jeffrey D., Slack, Elizabeth, Otte, Gabriel, Santisakultarm, Thom P., Iadecola, Costantino, Nishimura, Nozomi, Schaffer, Chris B.

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