Search Results - "Cruz Acuña, Ricardo"

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair by Cruz-Acuña, Ricardo, Quirós, Miguel, Farkas, Attila E., Dedhia, Priya H., Huang, Sha, Siuda, Dorothée, García-Hernández, Vicky, Miller, Alyssa J., Spence, Jason R., Nusrat, Asma, García, Andrés J.

“…In vitro differentiation of human intestinal organoids (HIOs) from pluripotent stem cells is an unparalleled system for creating complex, multicellular…”
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Understanding the cellular origin and progression of esophageal cancer using esophageal organoids by Sachdeva, Uma M., Shimonosono, Masataka, Flashner, Samuel, Cruz-Acuña, Ricardo, Gabre, Joel T., Nakagawa, Hiroshi

“…Three-dimensional (3D) organoids are a novel tool to model epithelial cell biology and human diseases of the esophagus. 3D organoid culture systems have been…”
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Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis by Enemchukwu, Nduka O, Cruz-Acuña, Ricardo, Bongiorno, Tom, Johnson, Christopher T, García, José R, Sulchek, Todd, García, Andrés J

“…Epithelial cells cultured within collagen and laminin gels proliferate to form hollow and polarized spherical structures, recapitulating the formation of a…”
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Engineered materials to model human intestinal development and cancer using organoids by Cruz-Acuña, Ricardo, García, Andrés J.

“…Human organoids provide constructive in vitro models of human development and disease, as these recapitulate important morphogenetic and functional features of…”
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Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium by Kabir, Mohammad Faujul, Karami, Adam L., Cruz-Acuña, Ricardo, Klochkova, Alena, Saxena, Reshu, Mu, Anbin, Murray, Mary Grace, Cruz, Jasmine, Fuller, Annie D., Clevenger, Margarette H., Chitrala, Kumaraswamy Naidu, Tan, Yinfei, Keith, Kelsey, Madzo, Jozef, Huang, Hugh, Jelinek, Jaroslav, Karakasheva, Tatiana, Hamilton, Kathryn E., Muir, Amanda B., Tétreault, Marie-Pier, Whelan, Kelly A.

“…Although morphologic progression coupled with expression of specific molecular markers has been characterized along the esophageal squamous differentiation…”
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Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer by Karakasheva, Tatiana A., Gabre, Joel T., Sachdeva, Uma M., Cruz-Acuña, Ricardo, Lin, Eric W., DeMarshall, Maureen, Falk, Gary W., Ginsberg, Gregory G., Yang, Zhaohai, Kim, Michele M., Diffenderfer, Eric S., Pitarresi, Jason R., Li, Jinyang, Muir, Amanda B., Hamilton, Kathryn E., Nakagawa, Hiroshi, Bass, Adam J., Rustgi, Anil K.

“…3D patient-derived organoids (PDOs) have been utilized to evaluate potential therapies for patients with different cancers. However, the use of PDOs created…”
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Emerging technologies provide insights on cancer extracellular matrix biology and therapeutics by Cruz-Acuña, Ricardo, Vunjak-Novakovic, Gordana, Burdick, Jason A., Rustgi, Anil K.

“…Recent engineering technologies have transformed traditional perspectives of cancer to include the important role of the extracellular matrix (ECM) in…”
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Quantifying epithelial cell proliferation on curved surfaces by Chang, Ya-Wen, Cruz-Acuña, Ricardo, Tennenbaum, Michael, Fragkopoulos, Alexandros A., García, Andrés J., Fernández-Nieves, Alberto

“…Out-of-plane curvature is an important, but poorly explored geometric parameter that influences cell behavior. We address the impact of curvature on epithelial…”
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Enhanced singlet oxygen production by photodynamic therapy and a novel method for its intracellular measurement by Pena Luengas, Sandra L, Marin, Gustavo Horacio, Aviles, Kevin, Cruz Acuña, Ricardo, Roque, Gustavo, Rodríguez Nieto, Felipe, Sanchez, Francisco, Tarditi, Adrián, Rivera, Luis, Mansilla, Eduardo

“…The generation of singlet oxygen (SO) in the presence of specific photosensitizers (PSs) or semiconductor quantum dots (QDs) and its application in…”
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Synthetic hydrogels mimicking basement membrane matrices to promote cell-matrix interactions by Cruz-Acuña, Ricardo, García, Andrés J.

“…Naturally-derived materials have been extensively used as 3D cellular matrices as their inherent bioactivity makes them suitable for the study of many cellular…”
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PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery by Cruz-Acuña, Ricardo, Quirós, Miguel, Huang, Sha, Siuda, Dorothée, Spence, Jason R., Nusrat, Asma, García, Andrés J.

“…In vitro differentiation of human pluripotent stem cell (hPSC)-derived organoids (HOs) facilitates the production of multicellular three-dimensional structures…”
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Identification of matrix physicochemical properties required for renal epithelial cell tubulogenesis by using synthetic hydrogels by Cruz-Acuña, Ricardo, Mulero-Russe, Adriana, Clark, Amy Y, Zent, Roy, García, Andrés J

“…Synthetic hydrogels with controlled physicochemical matrix properties serve as powerful tools to dissect cell-extracellular matrix (ECM) interactions that…”
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Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets by Cruz-Acuña, Ricardo, Kariuki, Secunda W, Sugiura, Kensuke, Karaiskos, Spyros, Plaster, Eleanor M, Loebel, Claudia, Efe, Gizem, Karakasheva, Tatiana, Gabre, Joel T, Hu, Jianhua, Burdick, Jason A, Rustgi, Anil K

“…Increased extracellular matrix (ECM) stiffness has been implicated in esophageal adenocarcinoma (EAC) progression, metastasis, and resistance to therapy…”
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Synthetic hydrogels engineered to promote collecting lymphatic vessel sprouting by Hooks, Joshua S.T., Bernard, Fabrice C., Cruz-Acuña, Ricardo, Nepiyushchikh, Zhanna, Gonzalez-Vargas, Yarelis, García, Andrés J., Dixon, J. Brandon

“…The lymphatic vasculature is an essential component of the body's circulation providing a network of vessels to return fluid and proteins from the tissue space…”
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p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression by Efe, Gizem, Dunbar, Karen J, Sugiura, Kensuke, Cunningham, Katherine, Carcamo, Saul, Karaiskos, Spyros, Tang, Qiaosi, Cruz-Acuña, Ricardo, Resnick-Silverman, Lois, Peura, Jessica, Lu, Chao, Hasson, Dan, Klein-Szanto, Andres J, Taylor, Alison M, Manfredi, James J, Prives, Carol, Rustgi, Anil K

“…TP53 mutations are frequent in esophageal squamous cell carcinoma (ESCC) and other SCCs and are associated with a proclivity for metastasis. Here, we report…”
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Quantum dots of ZnSe(S) doped with copper as nanophotocatalyst in the degradation of organic dyes by Alamo-Nole, Luis, Bailon-Ruiz, Sonia, Cruz-Acuña, Ricardo, Perales-Pérez, Oscar, Román, Félix R

“…Copper-doped quantum dots of ZnSe(S) synthesized via microwave-heating conditions were used as photocatalyst in the photo-degradation of methylene blue (MB),…”
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Abstract P114: Engineered hydrogel elucidates contributions of matrix mechanics to esophageal adenocarcinoma and identify matrix-activated therapeutic targets by Cruz-Acuña, Ricardo, Loebel, Claudia, Burdick, Jason A., Rustgi, Anil K.

“…Changes in the tumor microenvironment arbitrated by a stiffened ECM are associated with tumor aggression and enable increased propensity towards metastasis…”
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Publisher Correction: PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery by Cruz-Acuña, Ricardo, Quirós, Miguel, Huang, Sha, Siuda, Dorothée, Spence, Jason R., Nusrat, Asma, García, Andrés J.

“…In the version of this protocol originally published, the caption for Fig. 3 was erroneously placed with Fig. 4, and that for Fig. 4 was placed with Fig. 3…”
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Abstract 3838: Engineered hydrogel elucidates contributions of matrix mechanics to esophageal adenocarcinoma and identify matrix-activated therapeutic targets by Cruz-Acuña, Ricardo, Kariuki, Secunda W., Loebel, Claudia, Karakasheva, Tatiana, Gabre, Joel T., Burdick, Jason A., Rustgi, Anil K.

“…INTRODUCTION: Changes in the tumor microenvironment arbitrated by a stiffened ECM are associated with tumor aggression and enable increased propensity towards…”
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Su107 SINGLE CELL TRANSCRIPTOMIC ANALYSIS REVEALS CELLULAR DIVERSITY AND CELL FATE TRAJECTORIES IN MURINE ESOPHAGEAL EPITHELIUM by Karami, Adam, Kabir, Mohammad Faujul, Cruz-Acuna, Ricardo, Klochkova, Alena, Mu, Anbin, Whelan, Kelly A.

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