Search Results - "Cruz‐Herranz, Andres"

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies by Cruz-Herranz, Andrés, Balk, Lisanne J, Oberwahrenbrock, Timm, Saidha, Shiv, Martinez-Lapiscina, Elena H, Lagreze, Wolf A, Schuman, Joel S, Villoslada, Pablo, Calabresi, Peter, Balcer, Laura, Petzold, Axel, Green, Ari J, Paul, Friedemann, Brandt, Alexander U, Albrecht, Philipp

“…OBJECTIVE:To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. METHODS:A panel of experienced…”
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LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease by Jennings, Danna, Huntwork‐Rodriguez, Sarah, Vissers, Maurits F.J.M., Daryani, Vinay M., Diaz, Dolores, Goo, Marisa S., Chen, John J., Maciuca, Romeo, Fraser, Kyle, Mabrouk, Omar S., Wetering de Rooij, Jeroen, Heuberger, Jules A.A.C., Groeneveld, Geert Jan, Borin, Marie T., Cruz‐Herranz, Andrés, Graham, Danielle, Scearce‐Levie, Kimberly, De Vicente, Javier, Henry, Anastasia G., Chin, Peter, Ho, Carole, Troyer, Matthew D.

“…Background Leucine‐rich repeat kinase 2 (LRRK2) inhibition is a promising therapeutic approach for the treatment of Parkinson's disease (PD). Objective The aim…”
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Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib studies in healthy subjects and patients by Vissers, Maurits F. J. M., Heuberger, Jules A. A. C., Groeneveld, Geert Jan, Oude Nijhuis, Jerome, De Deyn, Peter Paul, Hadi, Salah, Harris, Jeffrey, Tsai, Richard M., Cruz‐Herranz, Andres, Huang, Fen, Tong, Vincent, Erickson, Rebecca, Zhu, Yuda, Scearce‐Levie, Kimberly, Hsiao‐Nakamoto, Jennifer, Tang, Xinyan, Chang, Megan, Fox, Brian M., Estrada, Anthony A., Pomponio, Robert J., Alonso‐Alonso, Miguel, Zilberstein, Moshe, Atassi, Nazem, Troyer, Matthew D., Ho, Carole

“…RIPK1 is a master regulator of inflammatory signaling and cell death and increased RIPK1 activity is observed in human diseases, including Alzheimer’s disease…”
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Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity by Schirmer, Lucas, Möbius, Wiebke, Zhao, Chao, Cruz-Herranz, Andrés, Ben Haim, Lucile, Cordano, Christian, Shiow, Lawrence R, Kelley, Kevin W, Sadowski, Boguslawa, Timmons, Garrett, Pröbstel, Anne-Katrin, Wright, Jackie N, Sin, Jung Hyung, Devereux, Michael, Morrison, Daniel E, Chang, Sandra M, Sabeur, Khalida, Green, Ari J, Nave, Klaus-Armin, Franklin, Robin Jm, Rowitch, David H

“…Glial support is critical for normal axon function and can become dysregulated in white matter (WM) disease. In humans, loss-of-function mutations of which…”
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Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis by Cruz-Herranz, Andrés, Dietrich, Michael, Hilla, Alexander M, Yiu, Hao H, Levin, Marc H, Hecker, Christina, Issberner, Andrea, Hallenberger, Angelika, Cordano, Christian, Lehmann-Horn, Klaus, Balk, Lisanne J, Aktas, Orhan, Ingwersen, Jens, von Gall, Charlotte, Hartung, Hans-Peter, Zamvil, Scott S, Fischer, Dietmar, Albrecht, Philipp, Green, Ari J

“…Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and…”
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Pridopidine Does Not Significantly Prolong the QTc Interval at the Clinically Relevant Therapeutic Dose by Darpo, Borje, Geva, Michal, Ferber, Georg, Goldberg, Yigal Paul, Cruz-Herranz, Andres, Mehra, Munish, Kovacs, Richard, Hayden, Michael R.

“…Introduction Pridopidine is a highly selective sigma-1 receptor (S1R) agonist in development for the treatment of Huntington’s disease (HD) and amyotrophic…”
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Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis by Cruz-Herranz, Andrés, Oertel, Frederike C, Kim, Kicheol, Cantó, Ester, Timmons, Garrett, Sin, Jung H, Devereux, Michael, Baker, Nicholas, Michel, Brady, Schubert, Ryan D, Rani, Lakshmisahithi, Cordano, Christian, Baranzini, Sergio E, Green, Ari J

“…Neurodegeneration mediates neurological disability in inflammatory demyelinating diseases of the CNS. The role of innate immune cells in mediating this damage…”
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Is diabetes an independent risk factor for in-hospital complications after a stroke? by Cruz-Herranz, Andrés, Fuentes, Blanca, Martínez-Sánchez, Patricia, Ruiz-Ares, Gerardo, Lara-Lara, Manuel, Sanz-Cuesta, Borja, Díez-Tejedor, Exuperio

“…Background Patients with diabetes mellitus (DM) are more likely to develop in‐hospital complications (IHCs) than patients without DM. In addition, they have…”
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Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study by Balk, Lisanne J., Cruz-Herranz, Andrés, Albrecht, Philipp, Arnow, Sam, Gelfand, Jeffrey M., Tewarie, Prejaas, Killestein, Joep, Uitdehaag, Bernard M. J., Petzold, Axel, Green, Ari J.

“…The objective of the study was to investigate the timing of central nervous system tissue atrophy in MS by evaluating longitudinal retinal volume changes in a…”
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Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4 by Sagan, Sharon A., Winger, Ryan C., Cruz-Herranz, Andrés, Nelson, Patricia A., Hagberg, Sarah, Miller, Corey N., Spencer, Collin M., Ho, Peggy P., Bennett, Jeffrey L., Levy, Michael, Levin, Marc H., Verkman, Alan S., Steinman, Lawrence, Green, Ari J., Anderson, Mark S., Sobel, Raymond A., Zamvil, Scott S.

“…Aquaporin-4 (AQP4)-specific T cells are expanded in neuromyelitis optica (NMO) patients and exhibit Th17 polarization. However, their pathogenic role in CNS…”
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Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats by Dietrich, Michael, Hecker, Christina, Hilla, Alexander, Cruz-Herranz, Andrés, Hartung, Hans-Peter, Fischer, Dietmar, Green, Ari, Albrecht, Philipp

“…Optical coherence tomography (OCT) is a fast, non-invasive, interferometric technique allowing high-resolution retinal imaging. It is an ideal tool for the…”
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Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy by Cordano, Christian, Sin, Jung H, Timmons, Garrett, Yiu, Hao H, Stebbins, Karin, Guglielmetti, Caroline, Cruz-Herranz, Andres, Xin, Wendy, Lorrain, Daniel, Chan, Jonah R, Green, Ari J

“…Many biomarkers in clinical neuroscience lack pathological certification. This issue is potentially a significant contributor to the limited success of…”
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The effect of telestroke systems among neighboring hospitals: more and better? The Madrid Telestroke Project by Martínez-Sánchez, Patricia, Miralles, Ambrosio, Sanz de Barros, Rosa, Prefasi, Daniel, Sanz-Cuesta, Borja E., Fuentes, Blanca, Ruiz-Ares, Gerardo, Martínez-Martínez, Marta, Miñano, Elena, Arévalo-Manso, Juan José, Correas-Callero, Elisa, Cruz-Herranz, Andrés, Díez-Tejedor, Exuperio

“…A telestroke system was established between a community hospital lacking an on-call neurologist and a comprehensive stroke center only 13 km away. Our goal was…”
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Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis by Ward, Michael E, Chen, Robert, Huang, Hsin-Yi, Ludwig, Connor, Telpoukhovskaia, Maria, Taubes, Ali, Boudin, Helene, Minami, Sakura S, Reichert, Meredith, Albrecht, Philipp, Gelfand, Jeffrey M, Cruz-Herranz, Andres, Cordano, Christian, Alavi, Marcel V, Leslie, Shannon, Seeley, William W, Miller, Bruce L, Bigio, Eileen, Mesulam, Marek-Marsel, Bogyo, Matthew S, Mackenzie, Ian R, Staropoli, John F, Cotman, Susan L, Huang, Eric J, Gan, Li, Green, Ari J

“…Heterozygous mutations in the gene lead to progranulin (PGRN) haploinsufficiency and cause frontotemporal dementia (FTD), a neurodegenerative syndrome of older…”
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Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4 by Sagan, Sharon A, Cruz-Herranz, Andrés, Spencer, Collin M, Ho, Peggy P, Steinman, Lawrence, Green, Ari J, Sobel, Raymond A, Zamvil, Scott S

“…While it is recognized that aquaporin-4 (AQP4)-specific T cells and antibodies participate in the pathogenesis of neuromyelitis optica (NMO), a human central…”
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Whole-body positional manipulators for ocular imaging of anaesthetised mice and rats: a do-it-yourself guide by Dietrich, Michael, Cruz-Herranz, Andrés, Yiu, Hao, Aktas, Orhan, Brandt, Alexander U, Hartung, Hans-Peter, Green, Ari, Albrecht, Philipp

“…BackgroundIn vivo retinal imaging of rodents has gained a growing interest in ophthalmology and neurology. The bedding of the animals with the possibility to…”
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Acute ischemic stroke patients with diabetes should not be excluded from intravenous thrombolysis by Fuentes, Blanca, Cruz-Herranz, Andrés, Martínez-Sánchez, Patricia, Rodríguez-Sanz, Ana, Ruiz Ares, Gerardo, Prefasi, Daniel, Sanz-Cuesta, Borja E., Lara-Lara, Manuel, Díez-Tejedor, Exuperio

“…The benefit of intravenous thrombolysis (IVT) has been questioned for patients with diabetes mellitus (DM) in cases of acute ischemic stroke (IS). Our…”
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Abstract 3648: Detection Of Paroxysmal Atrial Fibrillation In Patient With Acute Brain Ischemia Combining Cardiac And Holter Monitoring: Prevalence And Predictors by Martinez-Sanchez, Patricia, Correas Callero, Elisa, Cruz Herranz, Andres, Fuentes Gimeno, Blanca, Martin Montes, Angel, Mangas Guijarro, Maria de los Angeles, Ruiz Ares, Gerardo, Martinez Martinez, Marta, Diez-Tejedor, Exuperio

“…Abstract only INTRODUCTION: The yield of serial electrocardiograms (ECG) plus 72-hour cardiac monitoring and Holter monitoring in detection of paroxysmal…”
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Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination by Kapell, Hannah, Fazio, Luca, Dyckow, Julia, Schwarz, Sophia, Cruz-Herranz, Andrés, Mayer, Christina, Campos, Joaquin, D'Este, Elisa, Möbius, Wiebke, Cordano, Christian, Pröbstel, Anne-Katrin, Gharagozloo, Marjan, Zulji, Amel, Narayanan Naik, Venu, Delank, Anna, Cerina, Manuela, Müntefering, Thomas, Lerma-Martin, Celia, Sonner, Jana K, Sin, Jung Hyung, Disse, Paul, Rychlik, Nicole, Sabeur, Khalida, Chavali, Manideep, Srivastava, Rajneesh, Heidenreich, Matthias, Fitzgerald, Kathryn C, Seebohm, Guiscard, Stadelmann, Christine, Hemmer, Bernhard, Platten, Michael, Jentsch, Thomas J, Engelhardt, Maren, Budde, Thomas, Nave, Klaus-Armin, Calabresi, Peter A, Friese, Manuel A, Green, Ari J, Acuna, Claudio, Rowitch, David H, Meuth, Sven G, Schirmer, Lucas

“…Multiple sclerosis (MS) is a progressive inflammatory demyelinating disease of the CNS. Increasing evidence suggests that vulnerable neurons in MS exhibit…”
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The APOSTEL recommendations for reporting quantitative optical coherence tomography studies by Cameron, James R

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