Search Results - "Cruz, Peter"
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Inflammatory bowel disease in Asia: A systematic review
Published in Journal of gastroenterology and hepatology (01-08-2012)“…The incidence and prevalence of inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are lower in Asia than in the West…”
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Outcomes out to 12 months after sequential use of high‐dose tofacitinib following infliximab in acute severe ulcerative colitis
Published in Internal medicine journal (01-08-2023)“…Acute severe colitis (ASUC) remains a significant cause of morbidity in up to 25% of patients with ulcerative colitis during their disease course. We present…”
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Systematic Review and Meta-analysis: Optimal Salvage Therapy in Acute Severe Ulcerative Colitis
Published in Inflammatory bowel diseases (18-06-2019)“…Abstract Background Infliximab is an effective salvage therapy in acute severe ulcerative colitis; however, the optimal dosing strategy is unknown. We…”
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Clinical trial: Combination allopurinol‐thiopurine versus standard thiopurine in patients with IBD escalating to immunomodulators (the DECIDER study)
Published in Alimentary pharmacology & therapeutics (01-02-2024)“…Summary Background Thiopurines are established treatments for inflammatory bowel disease (IBD), yet concerns remain regarding their safety. Aim To evaluate the…”
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Systematic review and meta-analysis: evaluating response to empiric anti-TNF dose intensification for secondary loss of response in Crohn’s disease
Published in Therapeutic advances in gastroenterology (01-02-2022)“…Introduction: Anti-tumor necrosis factor (TNF) dose intensification represents an effective method of overcoming secondary loss of response (LOR); however, a…”
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Microbial Factors Associated with Postoperative Crohn's Disease Recurrence
Published in Journal of Crohn's and colitis (01-02-2017)“…The intestinal microbiota is a key antigenic driver in Crohn's disease [CD]. We aimed to identify changes in the gut microbiome associated with, and predictive…”
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An Overview of the Innate and Adaptive Immune System in Inflammatory Bowel Disease
Published in Inflammatory bowel diseases (01-01-2017)“…Inflammatory bowel diseases (IBDs) are thought to develop as a result of complex interactions between host genetics, the immune system and the environment…”
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Tumor‐stroma interactions differentially alter drug sensitivity based on the origin of stromal cells
Published in Molecular systems biology (01-08-2018)“…Due to tumor heterogeneity, most believe that effective treatments should be tailored to the features of an individual tumor or tumor subclass. It is still…”
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Robot-Accelerated Perovskite Investigation and Discovery
Published in Chemistry of materials (14-07-2020)“…Metal halide perovskites are a promising class of materials for next-generation photovoltaic and optoelectronic devices. The discovery and full…”
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10
Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford
Published in World journal of gastroenterology : WJG (14-08-2020)“…Vedolizumab (VDZ), a humanised monoclonal antibody that selectively inhibits integrins is approved for use in adult moderate to severe ulcerative colitis (UC)…”
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What to do when traditional rescue therapies fail in acute severe ulcerative colitis
Published in Intestinal research (01-10-2024)“…Acute severe ulcerative colitis (ASUC) is a medical emergency that affects approximately 25% of patients with ulcerative colitis at some point in time in their…”
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Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins
Published in Biochemistry (Easton) (15-02-2022)“…The strategic redesign of microbial biosynthetic pathways is a compelling route to access molecules of diverse structure and function in a potentially…”
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Defining management strategies for acute severe ulcerative colitis using predictive models: a simulation-modeling study
Published in Intestinal research (01-10-2024)“…Background/Aims: Robust management algorithms are required to reduce the residual risk of colectomy in acute severe ulcerative colitis (ASUC) refractory to…”
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Characterization of Microbial Population Shifts during Sample Storage
Published in Frontiers in microbiology (01-01-2012)“…The objective of this study was to determine shifts in the microbial community structure and potential function based on standard Integrated Ocean Drilling…”
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Comparison of Fecal Inflammatory Markers in Crohn's Disease
Published in Inflammatory bowel diseases (01-05-2016)“…Fecal biomarkers are used increasingly to monitor Crohn's disease (CD). However, the relative accuracy of different markers in identifying inflammation has…”
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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2012)“…To gain insight into the genomic basis of diffuse large B-cell lymphoma (DLBCL), we performed massively parallel whole-exome sequencing of 55 primary tumor…”
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Cost-effectiveness of Crohn’s disease post-operative care
Published in World journal of gastroenterology : WJG (14-04-2016)“…AIM: To define the cost-effectiveness of strategies, including endoscopy and immunosuppression, to prevent endoscopic recurrence of Crohn’s disease following…”
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Postoperative recurrent luminal Crohn's Disease: A systematic review
Published in Inflammatory bowel diseases (01-04-2012)“…Despite improved immunosuppressive therapy, surgical resection is still often required for uncontrolled inflammatory disease and the stenosing and perforating…”
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EHealth Technologies in Inflammatory Bowel Disease: A Systematic Review
Published in Journal of Crohn's and colitis (01-09-2016)“…Background and Aims: Electronic-health technologies (eHealth) such as Web-based interventions, virtual clinics, smart-phone applications, and telemedicine are…”
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Spontaneous Propionibacterium Acnes abscess with intraventricular rupture in an immunocompetent adult without prior neurosurgical intervention
Published in Clinical case reports (01-01-2022)“…Previously viewed as a culture contaminant, Propionibacterium Acnes can cause infection following neurosurgical intervention. Its role in brain abscess in the…”
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