Search Results - "Cruz, P.E."

Reproductive phenology of Isolatocereus dumortieri (Cactaceae) in semiarid scrub in central Mexico: Effect of rain during the dry season by Cruz, P.E., Pavón, N.P.

“…The giant cactus Isolatocereus dumortieri is a dominant species of the semiarid scrub of central Mexico. Its reproductive period is during the dry season, and…”
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Thermosensitivity of the reverse transcription process as an inactivation mechanism of lentiviral vectors by Carmo, M, Dias, J D, Panet, A, Coroadinha, A S, Carrondo, M J T, Alves, P M, Cruz, P E

“…Lentiviral vectors are an important tool for gene transfer research and gene therapy purposes. However, the low stability of these vectors affects their…”
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Off-the-shelf hepatocyte-like cells (HLCs): Characterization of cryopreserved human mesenchymal stem cell-derived HLCs by Cipriano, M., Belém, B., Rodrigues, J.S., Cruz, P.E., Cruz, H., Oliveira, N.G., Castro, M., Santos, J.M., Miranda, J.P.

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What Makes Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells Superior Immunomodulators When Compared to Bone Marrow Derived Mesenchymal Stromal Cells? by Bárcia, R. N., Santos, J. M., Filipe, M., Teixeira, M., Martins, J. P., Almeida, J., Água-Doce, A., Almeida, S. C. P., Varela, A., Pohl, S., Dittmar, K. E. J., Calado, S., Simões, S. I., Gaspar, M. M., Cruz, M. E. M., Lindenmaier, W., Graça, L., Cruz, H., Cruz, P. E.

“…MSCs derived from the umbilical cord tissue, termed UCX, were investigated for their immunomodulatory properties and compared to bone marrow-derived MSCs…”
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Insect cell growth evaluation during serum-free adaptation in stirred suspension cultures by Cruz, P.E, Moreira, J.L, Carrondo, M.J.T

“…Sf-9 insect cells were adapted to three different serum-free media 9SF900II, EXCELL 401 and IPL/41 supplemented) in 125 ml stirred vessels by gradually…”
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Screening of Novel Excipients for Improving the Stability of Retroviral and Adenoviral Vectors by Cruz, Pedro E., Silva, Ana Carina, Roldão, António, Carmo, Marlene, Carrondo, Manuel J. T., Alves, Paula M.

“…In the past decade there has been an increase in the application of viral vectors in the laboratory and clinical trials of human gene therapy, retroviral and…”
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Distribución espacial de lombrices de tierra y propiedades de un Inceptisol en la ceja de selva peruana by MESTANZA NOVOA, C.J., ZOROGASTÚA CRUZ, P.E

“…Resumen Las lombrices de tierra son los agentes más estudiados de la macrofauna del suelo. La influencia de su actividad sobre las propiedades del suelo se ha…”
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Effect of medium sugar source on the production of retroviral vectors for gene therapy by Coroadinha, A.S., Ribeiro, J., Roldão, A., Cruz, P.E., Alves, P.M., Merten, O.-W., Carrondo, M.J.T.

“…The production of gene therapy retroviral vectors presents many difficulties, mainly due to vector instability and low cell productivities hampering the…”
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Purification of adenoviral vectors using expanded bed chromatography by Peixoto, C., Ferreira, T.B., Carrondo, M.J.T., Cruz, P.E., Alves, P.M.

“…The increasing numbers of pre-clinical and clinical trials where recombinant adenoviral vectors are used for gene therapy and vaccination require the…”
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Quantitation of MLV-based retroviral vectors using real-time RT-PCR by Carmo, M, Peixoto, C, Coroadinha, A.S, Alves, P.M, Cruz, P.E, Carrondo, M.J.T

“…Murine leukaemia virus-based vectors quantitation is a time consuming process that can take up to five days. In order to reduce this time a real-time RT-PCR…”
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Comparison of Different Bioreactor Systems for the Production of High Titer Retroviral Vectors by Merten, O.-W., Cruz, P. E., Rochette, C., Geny-Fiamma, C., Bouquet, C., Gonçalves, D., Danos, O., Carrondo, M. J. T.

“…Improved, human‐based packaging cell lines allow the production of high‐titer, RCR‐free retroviral vectors. The utility of these cell lines for the production…”
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Integrated process optimization: lessons from retrovirus and virus-like particle production by Cruz, P.E, Maranga, L, Carrondo, M.J.T

“…The optimization of production and purification processes is usually approached by engineers from a strictly biotechnological point of view. The present paper…”
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Optimization of the production of virus-like particles in insect cells by Cruz, Pedro E., Cunha, António, Peixoto, Cristina C., Clemente, João, Moreira, José L., Carrondo, Manuel J. T.

“…In this work the maximal operational hydrodynamic conditions (agitation and aeration rate) that cause no adverse effect in Sf‐9 cells growth in SF900II…”
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A novel immunization method to induce cytotoxic T-lymphocyte responses (CTL) against plasmid-encoded herpes simplex virus type-1 glycoprotein D1Presented in part: ASBMB/ASIP/AAI Joint Meeting, New Orleans, June 1996 (Abstract # 470) and Ph.D. thesis, Wright State University, August 1996.1 by Cruz, P.E., Khalil, P.L., Dryden, T.D., Chiou, H.C., Fink, P.S., Berberich, S.J., Bigley, N.J.

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Modeling Retrovirus Production for Gene Therapy. 1. Determination of Optimal Bioreaction Mode and Harvest Strategy by Cruz, Pedro E., Almeida, Jonas S., Murphy, Patrick N., Moreira, José L., Carrondo, Manuel J. T.

“…Although retroviruses are a promising tool for gene therapy, there are two major problems limiting the establishment of viable industrial processes: retrovirus…”
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Modeling Retrovirus Production for Gene Therapy. 2. Integrated Optimization of Bioreaction and Downstream Processing by Cruz, Pedro E., Gonçalves, Délia, Almeida, Jonas, Moreira, José L., Carrondo, Manuel J. T.

“…In this work a model envisaging the integrated optimization of bioreaction and downstream processing is presented. This model extends the work presented in…”
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A novel immunization method to induce cytotoxic T-lymphocyte responses (CTL) against plasmid-encoded herpes simplex virus type-1 glycoprotein D by Cruz, P.E., Khalil, P.L., Dryden, T.D., Chiou, H.C., Fink, P.S., Berberich, S.J., Bigley, N.J.

“…DNA molecules complexed with an asialoglycoprotein–polycation conjugate, consisting of asialoorosomucoid (ASOR) coupled to poly- l-lysine, can enter…”
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Cryopreservation of yamú ( Brycon amazonicus) sperm for large scale fertilization by Velasco-Santamaría, Yohana M., Medina-Robles, Víctor M., Cruz-Casallas, Pablo E.

“…To determine the effect of straw size and thawing temperature on cryopreserved sperm quality of yamú ( Brycon amazonicus), ovulation and spermiation were…”
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Acute and chronic stress and the inflammatory response in hyperprolactinemic rats by Ochoa-Amaya, J E, Malucelli, B E, Cruz-Casallas, P E, Nasello, A G, Felicio, L F, Carvalho-Freitas, M I R

“…Prolactin (PRL), a hormone produced by the pituitary gland, has multiple physiological functions, including immunoregulation. PRL can also be secreted in…”
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Effect of Viscosity upon Hydrodynamically Controlled Natural Aggregates of Animal Cells Grown in Stirred Vessels by Moreira, José L., Santana, Paula C., Feliciano, Ana S., Cruz, Pedro E., Racher, Andrew J., Griffiths, J. Bryan, Carrondo, Manuel J. T.

“…The effect of medium viscosity upon cell growth and aggregate characteristics of baby hamster kidney (BHK) cells cultivated in stirred tanks was evaluated. Two…”
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