Search Results - "Cruz, Helder J"

Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells by Cruz, H.J, Moreira, J.L, Carrondo, M.J.T

“…The present work aims at characterizing the regulatory mechanisms of metabolism and product formation of BHK cells producing a recombinant antibody/cytokine…”
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Therapeutic angiogenesis induced by human umbilical cord tissue-derived mesenchymal stromal cells in a murine model of hindlimb ischemia by Pereira, Ana Rita S, Mendes, Teresa F, Ministro, Augusto, Teixeira, Mariana, Filipe, Mariana, Santos, Jorge M, Bárcia, Rita N, Goyri-O'Neill, J, Pinto, Fausto, Cruz, Pedro E, Cruz, Helder J, Santos, Susana Constantino Rosa

“…Mesenchymal stem cells derived from human umbilical cord tissue, termed UCX®, have the potential to promote a full range of events leading to tissue…”
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Optical biosensor based on nitrite reductase immobilised in controlled pore glass by Rosa, Carla C, Cruz, Helder J, Vidal, Monica, Oliva, Abel G

“…The increasing concentration of nitrite in groundwater, rivers and lakes brings serious risks to the public health and to the environment. The aim of this work…”
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Establishment of optimal conditions for long-term culture of erythrocytic stages of Theileria uilenbergi by Miranda, Joana P G, Nascimento, Elisabete M, Cruz, Helder J, Yin, Hong, Zweygarth, Erich, Oliva, Abel G

“…To establish optimal conditions for long-term culture of the erythrocytic stage of Theileria uilenbergi. Red blood cells from 3 splenectomized sheep…”
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Immunosensors for diagnostic applications by Cruz, Helder J, Rosa, Carla C, Oliva, Abel G

“…Immunosensors can play an important role in the improvement of veterinary diagnostics in areas such as the diagnosis of diseases, drug detection and food…”
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Metabolically optimised BHK cell fed-batch cultures by Cruz, Helder J, Moreira, José L, Carrondo, Manuel J.T

“…The aim of this work was the optimisation of a fed-batch culture by metabolic confinement of BHK21 cells producing an antibody/cytokine fusion protein with…”
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Spherical vs. Granular Immobilization Support Selection and Performance on an Optical Flow Cell Immunosensor Based on the Fluorescence of Cyanine-5 by Silvestre, Óscar F., Silva, Marta G., Oliva, Abel G., Cruz, Helder J.

“…A spherical porous glass support Trisoperl ® (TRISO) with four pore diameters (ø 47.8; 55.9; 102.6, and 108.8 nm) was characterized and selected for…”
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Metabolic shifts do not influence the glycosylation patterns of a recombinant fusion protein expressed in BHK cells by Cruz, Helder J., Peixoto, Cristina M., Nimtz, Manfred, Alves, Paula M., Dias, Elsa M., Moreira, José L., Carrondo, Manuel J. T.

“…BHK‐21 cells expressing a human IgG‐IL2 fusion protein, with potential application in tumor‐targeted therapy, were grown under different nutrient conditions in…”
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Product quality of a recombinant fusion protein expressed in immobilised baby hamster kidney cells grown in protein-free medium by Cruz, Helder J, Dias, Elsa M, Peixoto, Cristina M, Moreira, José L, Carrondo, Manuel Jt

“…Baby hamster kidney cells producing a recombinant IgG-IL2 fusion protein were grown as spinner batch cultures in a protein-free medium, with cells immobilised…”
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Adaptation of BHK cells producing a recombinant protein to serum-free media and protein-free medium by CRUZ, H. J, MOREIRA, J. L, STACEY, G, DIAS, E. M, HAYES, K, LOOBY, D, GRIFFITHS, B, CARRONDO, M. J. T

“…In this work a recombinant BHK21 clone producing a fusion protein with potential application in tumour target therapy was adapted to five different serum-free…”
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