Search Results - "Cruz, Hélder"

Comparison of Anesthetic Depth Indexes Based on Thalamocortical Local Field Potentials in Rats by SILVA, Aura, CARDOSO-CRUZ, Hélder, SILVA, Francisco, GALHARDO, Vasco, ANTUNES, Luís

“…Local field potentials may allow a more precise analysis of the brain electrical activity than the electroencephalogram. In this study, local field potentials…”
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Consistent Long-Term Therapeutic Efficacy of Human Umbilical Cord Matrix-Derived Mesenchymal Stromal Cells After Myocardial Infarction Despite Individual Differences and Transient Engraftment by Laundos, Tiago L, Vasques-Nóvoa, Francisco, Gomes, Rita N, Sampaio-Pinto, Vasco, Cruz, Pedro, Cruz, Hélder, Santos, Jorge M, Barcia, Rita N, Pinto-do-Ó, Perpétua, Nascimento, Diana S

“…Human mesenchymal stem cells gather special interest as a universal and feasible add-on therapy for myocardial infarction (MI). In particular, human umbilical…”
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Corrigendum: Consistent long-term therapeutic efficacy of human umbilical cord matrix-derived mesenchymal stromal cells after myocardial infarction despite individual differences and transient engraftment by Laundos, Tiago L., Vasques-Nóvoa, Francisco, Gomes, Rita N., Sampaio-Pinto, Vasco, Cruz, Pedro, Cruz, Hélder, Santos, Jorge M., Barcia, Rita N., Pinto-do-Ó, Perpétua, Nascimento, Diana S.

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Altered prefrontal‐striatal theta‐band oscillatory dynamics underlie working memory deficits in neuropathic pain rats by Cardoso‐Cruz, Helder, Laranjeira, Inês, Monteiro, Clara, Galhardo, Vasco

“…Background Prelimbic medial prefrontal cortex (PL‐mPFC) and nucleus accumbens core region (NAcc) play an important role in supporting several executive…”
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A serum-free media formulation for cultured meat production supports bovine satellite cell differentiation in the absence of serum starvation by Messmer, Tobias, Klevernic, Iva, Furquim, Carolina, Ovchinnikova, Ekaterina, Dogan, Arin, Cruz, Helder, Post, Mark J, Flack, Joshua E

“…Cultured meat production requires the robust differentiation of satellite cells into mature muscle fibres without the use of animal-derived components. Current…”
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The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis by Miranda, Joana P, Camões, Sérgio P, Gaspar, Maria M, Rodrigues, Joana S, Carvalheiro, Manuela, Bárcia, Rita N, Cruz, Pedro, Cruz, Helder, Simões, Sandra, Santos, Jorge M

“…Rheumatoid arthritis (RA) is an autoimmune disorder whose treatment is mostly restricted to pain and symptom management and to the delay of joint destruction…”
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Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing by Santos, Jorge M, Camões, Sérgio P, Filipe, Elysse, Cipriano, Madalena, Barcia, Rita N, Filipe, Mariana, Teixeira, Mariana, Simões, Sandra, Gaspar, Manuela, Mosqueira, Diogo, Nascimento, Diana S, Pinto-do-Ó, Perpétua, Cruz, Pedro, Cruz, Helder, Castro, Matilde, Miranda, Joana P

“…The secretion of trophic factors by mesenchymal stromal cells has gained increased interest given the benefits it may bring to the treatment of a variety of…”
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Altered Brain Expression of DNA Methylation and Hydroxymethylation Epigenetic Enzymes in a Rat Model of Neuropathic Pain by Rodrigues, Diogo, Monteiro, Clara, Cardoso-Cruz, Helder, Galhardo, Vasco

“…The role of epigenetics in chronic pain at the supraspinal level is yet to be fully characterized. DNA histone methylation is crucially regulated by de novo…”
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Instability of spatial encoding by CA1 hippocampal place cells after peripheral nerve injury by Cardoso-Cruz, Helder, Lima, Deolinda, Galhardo, Vasco

“…Several authors have shown that the hippocampus responds to painful stimulation and suggested that prolonged painful conditions could lead to abnormal…”
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Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling after myocardial infarction by proangiogenic, antiapoptotic, and endogenous cell-activation mechanisms by Santos Nascimento, Diana, Mosqueira, Diogo, Sousa, Luís Moura, Teixeira, Mariana, Filipe, Mariana, Resende, Tatiana Pinho, Araújo, Ana Francisca, Valente, Mariana, Almeida, Joana, Martins, José Paulo, Santos, Jorge Miguel, Bárcia, Rita Nogueira, Cruz, Pedro, Cruz, Helder, Pinto-do-Ó, Perpétua

“…Among the plethora of cells under investigation to restore a functional myocardium, mesenchymal stromal cells (MSCs) have been granted considerable interest…”
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Selective optogenetic inhibition of medial prefrontal glutamatergic neurons reverses working memory deficits induced by neuropathic pain by Cardoso-Cruz, Helder, Paiva, Pedro, Monteiro, Clara, Galhardo, Vasco

“…Stability of local medial prefrontal cortex (mPFC) network activity is believed to be critical for sustaining cognitive processes such as working memory (WM)…”
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The Human Umbilical Cord Tissue-Derived MSC Population UCX(®) Promotes Early Motogenic Effects on Keratinocytes and Fibroblasts and G-CSF-Mediated Mobilization of BM-MSCs When Transplanted In Vivo by Miranda, Joana P, Filipe, Elysse, Fernandes, Ana Sofia, Almeida, Joana M, Martins, José P, De la Fuente, Alexandre, Abal, Miguel, Barcia, Rita N, Cruz, Pedro, Cruz, Helder, Castro, Matilde, Santos, Jorge M

“…Mesenchymal stromal cells (MSCs) play an important role in tissue regeneration mainly through the secretion of trophic factors that enhance the repair of…”
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The role of human umbilical cord tissue-derived mesenchymal stromal cells (UCX®) in the treatment of inflammatory arthritis by Santos, Jorge M, Bárcia, Rita N, Simões, Sandra I, Gaspar, Manuela M, Calado, Susana, Agua-Doce, Ana, Almeida, Sílvia C P, Almeida, Joana, Filipe, Mariana, Teixeira, Mariana, Martins, José P, Graça, Luís, Cruz, Maria E M, Cruz, Pedro, Cruz, Helder

“…ECBio has developed proprietary technology to consistently isolate, expand and cryopreserve a well-characterized population of stromal cells from human…”
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Therapeutic angiogenesis induced by human umbilical cord tissue-derived mesenchymal stromal cells in a murine model of hindlimb ischemia by Pereira, Ana Rita S, Mendes, Teresa F, Ministro, Augusto, Teixeira, Mariana, Filipe, Mariana, Santos, Jorge M, Bárcia, Rita N, Goyri-O'Neill, J, Pinto, Fausto, Cruz, Pedro E, Cruz, Helder J, Santos, Susana Constantino Rosa

“…Mesenchymal stem cells derived from human umbilical cord tissue, termed UCX®, have the potential to promote a full range of events leading to tissue…”
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Increased fronto-hippocampal connectivity in the Prrxl1 knockout mouse model of congenital hypoalgesia by Monteiro, Clara, Cardoso-Cruz, Helder, Matos, Mariana, Dourado, Margarida, Lima, Deolinda, Galhardo, Vasco

“…Despite the large number of studies addressing how prolonged painful stimulation affects brain functioning, there are only a handful of studies aimed at…”
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Dynamics of Lateral Habenula–Ventral Tegmental Area Microcircuit on Pain-Related Cognitive Dysfunctions by Pereira, Ana Raquel, Alemi, Mobina, Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder

“…Chronic pain is a health problem that affects the ability to work and perform other activities, and it generally worsens over time. Understanding the complex…”
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Role of Glutamatergic Projections from Lateral Habenula to Ventral Tegmental Area in Inflammatory Pain-Related Spatial Working Memory Deficits by Alemi, Mobina, Pereira, Ana Raquel, Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder

“…The lateral habenula (LHb) and the ventral tegmental area (VTA), which form interconnected circuits, have important roles in the crucial control of sensory and…”
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Impaired spatial memory performance in a rat model of neuropathic pain is associated with reduced hippocampus-prefrontal cortex connectivity by Cardoso-Cruz, Helder, Lima, Deolinda, Galhardo, Vasco

“…Chronic pain patients commonly complain of working memory deficits, but the mechanisms and brain areas underlying this cognitive impairment remain elusive. The…”
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Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells by Cruz, H.J, Moreira, J.L, Carrondo, M.J.T

“…The present work aims at characterizing the regulatory mechanisms of metabolism and product formation of BHK cells producing a recombinant antibody/cytokine…”
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Orbitostriatal encoding of reward delayed gratification and impulsivity in chronic pain by Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder

“…[Display omitted] •Chronic pain underlies central network malplasticity.•OFC-NAc dysfunctions may contribute to impairments in time-reward…”
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