Search Results - "Cruz, Deu John M"

Active reassortment of H9 influenza viruses between wild birds and live-poultry markets in Korea by Moon, Ho Jin, Song, Min Suk, Cruz, Deu John M, Park, Kuk Jin, Pascua, Philippe Noriel Q, Lee, Jun Han, Baek, Yun Hee, Choi, Dong Ho, Choi, Young Ki, Kim, Chul Joong

“…Surveillance of H9 avian influenza viruses in Korean live-poultry markets from September 2004 through October 2007 was carried out to investigate active…”
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Comparative Pharmacodynamics of Three Different Botulinum Toxin Type A Preparations following Repeated Intramuscular Administration in Mice by Byun, Jaeyoon, Kwak, Seongsung, Kwon, Jin-Hee, Shin, Minhee, Lee, Dong-Kyu, Rhee, Chang-Hoon, Kang, Won-ho, Oh, Jae-Wook, Cruz, Deu John M

“…Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily…”
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Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion by Park, Jung-Eun, Cruz, Deu John M., Shin, Hyun-Jin

“…Porcine epidemic diarrhea virus (PEDV) infection in Vero cells is facilitated by trypsin through an undefined mechanism. The present study describes the mode…”
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Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library by Cruz, Deu John M, Bonotto, Rafaela M, Gomes, Rafael G B, da Silva, Camila T, Taniguchi, Juliana B, No, Joo Hwan, Lombardot, Benoit, Schwartz, Olivier, Hansen, Michael A E, Freitas-Junior, Lucio H

“…Chikungunya virus (CHIKV) is a mosquito-borne arthrogenic alphavirus that causes acute febrile illness in humans accompanied by joint pains and in many cases,…”
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Comparative Analysis of Hyaluronidase-Mediated Degradation Among Seven Hyaluronic Acid Fillers in Hairless Mice by Kwak, Seong Sung, Yoon, Kwang Ho, Kwon, Jin Hee, Kang, Won-Ho, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Cruz, Deu John M, Son, Woo-Chan

“…Hyaluronic acid (HA) is the most common injectable dermal filler used for soft-tissue augmentation, and can be removed non-surgically by directly injecting…”
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High content screening of a kinase-focused library reveals compounds broadly-active against dengue viruses by Cruz, Deu John M, Koishi, Andrea Cristine, Taniguchi, Juliana Bosso, Li, Xiaolan, Milan Bonotto, Rafaela, No, Joo Hwan, Kim, Keum Hyun, Baek, Sungmin, Kim, Hee Young, Windisch, Marc Peter, Pamplona Mosimann, Ana Luiza, de Borba, Luana, Liuzzi, Michel, Hansen, Michael Adsetts Edberg, Duarte dos Santos, Claudia Nunes, Freitas-Junior, Lucio Holanda

“…Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and…”
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Trypsin-induced hemagglutination activity of porcine epidemic diarrhea virus by Park, Jung-Eun, Cruz, Deu John M, Shin, Hyun-Jin

“…The hemagglutination (HA) activity of porcine epidemic diarrhea virus (PEDV) was investigated. Two cell-adapted strains of PEDV (KPEDV-9 and SM98LVec) were…”
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Comparison of clinical features and hematologic abnormalities between dengue fever and dengue hemorrhagic fever among children in the Philippines by Carlos, Celia C, Oishi, Kazunori, Cinco, Maria T D D, Mapua, Cynthia A, Inoue, Shingo, Cruz, Deu John M, Pancho, Mary Ann M, Tanig, Carol Z, Matias, Ronald R, Morita, Kouichi, Natividad, Filipinas F, Igarashi, Akira, Nagatake, Tsuyoshi

“…To demonstrate the differences of clinical features and hematologic abnormalities between dengue fever (DF) and dengue hemorrhagic fever (DHF), 359 pediatric…”
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Comparative Pharmacodynamics Study of 3 Different Botulinum Toxin Type A Preparations in Mice by Kwak, Seongsung, Kang, Won-ho, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Cruz, Deu John M.

“…BACKGROUNDA new complexing protein-free botulinum toxin Type A (CBoNT) with the same mechanism of action as the botulinum toxin complex onabotulinumtoxinA…”
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Clathrin- and serine proteases-dependent uptake of porcine epidemic diarrhea virus into Vero cells by Park, Jung-Eun, Cruz, Deu John M., Shin, Hyun-Jin

“…•PEDV enters Vero cells via clathrin-mediated endocytosis.•PEDV entry in Vero cells is low pH sensitive.•PEDV requires serine proteolysis during entry. Porcine…”
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Identification of pyrrolo[3,2-c]pyridin-4-amine compounds as a new class of entry inhibitors against influenza viruses in vitro by Chang, So Young, Cruz, Deu John M., Ko, Yoonae, Min, Ji-Young

“…Various influenza virus entry inhibitors are being developed as therapeutic antiviral agents in ongoing preparation for emerging influenza viruses,…”
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Combination of PD-1 Checkpoint Blockade and Botulinum Toxin Type A1 Improves Antitumor Responses in Mouse Tumor Models of Melanoma and Colon Carcinoma by Kwak, Seongsung, Lee, Ji-Young, Kim, Min Ju, Lee, Hyo Jin, Lee, Dong-Kyu, Kang, Jiyeon, Kang, Won-ho, Son, Woo-Chan, Cruz, Deu John M.

“…Tumor innervation has been shown to be utilized by some solid cancers to support tumor initiation, growth, progression, and metastasis, as well as confer…”
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The GPRLQPY motif located at the carboxy-terminal of the spike protein induces antibodies that neutralize Porcine epidemic diarrhea virus by Cruz, Deu John M., Kim, Chul-Joong, Shin, Hyun-Jin

“…The spike protein of Porcine epidemic diarrhea virus is the main surface glycoprotein involved in virus attachment and entry and therefore is the target of…”
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Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei by Faria, Joana, Moraes, Carolina B, Song, Rita, Pascoalino, Bruno S, Lee, Nakyung, Siqueira-Neto, Jair L, Cruz, Deu John M, Parkinson, Tanya, Ioset, Jean-Robert, Cordeiro-da-Silva, Anabela, Freitas-Junior, Lucio H

“…Human African trypanosomiasis (HAT) is a vector-transmitted tropical disease caused by the protozoan parasite Trypanosoma brucei. High-throughput screening…”
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Kinome siRNA screen identifies novel cell-type specific dengue host target genes by KWON, Yong-Jun, JINYEONG HEO, WONG, Hazel E. E, CRUZ, Deu John M, VELUMANI, Sumathy, DA SILVA, Camila T, MOSIMANN, Ana Luiza P, DUARTE DOS SANTOS, Claudia N, FREITAS, Lucio H, FINK, Katja

“…Dengue is a global emerging infectious disease, with no specific treatment available. To identify novel human host cell targets important for dengue virus…”
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Phage-displayed peptides having antigenic similarities with porcine epidemic diarrhea virus (PEDV) neutralizing epitopes by Cruz, Deu John M., Kim, Chul-Joong, Shin, Hyun-Jin

“…Seven-mer phage random peptide libraries were panned against 2C10, a monoclonal antibody that showed neutralizing activities against PEDV. Recombinant M13…”
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Application of a focus formation assay for detection and titration of porcine epidemic diarrhea virus by Cruz, Deu John M., Shin, Hyun-Jin

“…A focus formation assay (FFA) for detection and titration of porcine epidemic diarrhea virus (PEDV) in a micro-culture system using Vero cells and PAP staining…”
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Development of a Novel Recombinant Heamagglutinin-Neuramindase Elisa (rHN-ELISA) for Evaluation of Humoral Immunity in Chicken Vaccinated Against Newcastle Disease Virus (NDV) by Moon, Ho-Jin, Park, Jung-Eun, Yoon, Hyeon, M. Cruz, Deu John, Kim, Chul-Joong, Shin, Hyun-Jin

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Comparative Analysis of Hyaluronidase-Mediated Degradation Among Seven Hyaluronic Acid Fillers in Hairless Mice by Kwak, Seong Sung, Yoon, Kwang Ho, Kwon, Jin Hee, Kang, Won-Ho, Rhee, Chang-Hoon, Yang, Gi-Hyeok, Deu, John M. Cruz, Son, Woo-Chan

“…Purpose: Hyaluronic acid (HA) is the most common injectable dermal filler used for soft-tissue augmentation, and can be removed non-surgically by directly…”
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Development of a cell-based high throughput assay system and IN-house image analysis software for screening of active compounds against dengue virus by Cruz, Deu John M, Koishi, Andrea C, Pamplona, Ana Luiza M, Genovesio, Auguste, Duarte dos Santos, Claudia N, Freitas-Junior, Lucio

“…According to the World Health Organization, approximately 2.5 billion people live in dengue endemic countries, with an estimated 50 million cases occurring…”
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