Search Results - "Cruz, B A."

Exosome isolation from distinct biofluids using precipitation and column-based approaches by Soares Martins, Tânia, Catita, José, Martins Rosa, Ilka, A B da Cruz E Silva, Odete, Henriques, Ana Gabriela

“…The potential of exosomes as biomarker resources for diagnostics, prognostics and even for therapeutics is an area of intense research. Despite the various…”
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Nuclear envelope dysfunction and its contribution to the aging process by Martins, Filipa, Sousa, Jéssica, Pereira, Cátia D., Cruz e Silva, Odete A. B., Rebelo, Sandra

“…The nuclear envelope (NE) is the central organizing unit of the eukaryotic cell serving as a genome protective barrier and mechanotransduction interface…”
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Systems biology analysis of publicly available transcriptomic data reveals a critical link between AKR1B10 gene expression, smoking and occurrence of lung cancer by Cubillos-Angulo, Juan M, Fukutani, Eduardo R, Cruz, Luís A B, Arriaga, María B, Lima, João Victor, Andrade, Bruno B, Queiroz, Artur T L, Fukutani, Kiyoshi F

“…Cigarette smoking is associated with an increased risk of developing respiratory diseases and various types of cancer. Early identification of such unfavorable…”
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Nuclear envelope dynamics during mammalian spermatogenesis: new insights on male fertility by Pereira, Cátia D., Serrano, Joana B., Martins, Filipa, Cruz e Silva, Odete A. B., Rebelo, Sandra

“…ABSTRACT The production of highly specialized spermatozoa from undifferentiated spermatogonia is a strictly organized and programmed process requiring…”
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Tuberculosis-associated anemia is linked to a distinct inflammatory profile that persists after initiation of antitubercular therapy by Gil-Santana, Leonardo, Cruz, Luís A. B., Arriaga, María B., Miranda, Pryscila F. C., Fukutani, Kiyoshi F., Silveira-Mattos, Paulo S., Silva, Elisangela C., Oliveira, Marina G., Mesquita, Eliene D. D., Rauwerdink, Anneloek, Cobelens, Frank, Oliveira, Martha M., Kritski, Afranio, Andrade, Bruno B.

“…Pulmonary tuberculosis (PTB) is associated with chronic inflammation and anemia. How anemia impacts systemic inflammation in PTB patients undergoing…”
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Chronic hepatitis B virus infection drives changes in systemic immune activation profile in patients coinfected with Plasmodium vivax malaria by Cruz, Luís A B, Moraes, Marina O A, Queiroga-Barros, Matheus R, Fukutani, Kiyoshi F, Barral-Netto, Manoel, Andrade, Bruno B

“…Plasmodium vivax and Hepatitis B virus (HBV) are globally outspread in similar geographic regions. The concurrence of both infections and its association with…”
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Distinct inflammatory profile underlies pathological increases in creatinine levels associated with Plasmodium vivax malaria clinical severity by Cruz, Luís A B, Barral-Netto, Manoel, Andrade, Bruno B

“…Although Plasmodium vivax infection is a frequent cause of malaria worldwide, severe presentations have been more regularly described only in recent years. In…”
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Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease by Soares Martins, Tânia, Marçalo, Rui, Ferreira, Maria, Vaz, Margarida, Silva, Raquel M, Martins Rosa, Ilka, Vogelgsang, Jonathan, Wiltfang, Jens, da Cruz E Silva, Odete A B, Henriques, Ana Gabriela

“…The potential of exosomes as biomarker resources for diagnostics and even for therapeutics has intensified research in the field, including in the context of…”
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Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease by Soares Martins, Tânia, Pelech, Steven, Ferreira, Maria, Pinho, Beatriz, Leandro, Kevin, de Almeida, Luís Pereira, Breitling, Benedict, Hansen, Niels, Esselmann, Hermann, Wiltfang, Jens, da Cruz E Silva, Odete A B, Henriques, Ana Gabriela

“…Phosphorylation plays a key role in Alzheimer's disease (AD) pathogenesis, impacting distinct processes such as amyloid-beta (Aβ) peptide production and tau…”
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Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts by Viegas, Diana, Pereira, Cátia D, Martins, Filipa, Mateus, Tiago, da Cruz E Silva, Odete A B, Herdeiro, Maria Teresa, Rebelo, Sandra

“…Myotonic dystrophy type 1 (DM1) is a hereditary and multisystemic disease characterized by myotonia, progressive distal muscle weakness and atrophy. The…”
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Effect of preoperative chemotherapy on the outcome of women with operable breast cancer by Fisher, B, Bryant, J, Wolmark, N, Mamounas, E, Brown, A, Fisher, E R, Wickerham, D L, Begovic, M, DeCillis, A, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Hoehn, J L, Lees, A W, Dimitrov, N V, Bear, H D

“…To determine, in women with primary operable breast cancer, if preoperative doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan; AC) therapy yields a better…”
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Effect of preoperative chemotherapy on the outcome of women with operable breast cancer by Fisher, B, Bryant, J, Wolmark, N, Mamounas, E, Brown, A, Fisher, E R, Wickerham, D L, Begovic, M, DeCillis, A, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Hoehn, J L, Lees, A W, Dimitrov, N V, Bear, H D

“…To determine, in women with primary operable breast cancer, if preoperative doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan; AC) therapy yields a better…”
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Chronic Hepatitis B Infection Is Associated with Increased Molecular Degree of Inflammatory Perturbation in Peripheral Blood by Vinhaes, Caian L, Cruz, Luís A B, Menezes, Rodrigo C, Carmo, Thomas A, Arriaga, María B, Queiroz, Artur T L, Barral-Netto, Manoel, Andrade, Bruno B

“…Hepatitis B virus (HBV) infection remains a major public health concern. The interaction between HBV and the host inflammatory response is an important…”
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Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18 by Fisher, B, Brown, A, Mamounas, E, Wieand, S, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Fisher, E R, Wickerham, D L, Wolmark, N, DeCillis, A, Hoehn, J L, Lees, A W, Dimitrov, N V

“…To determine whether preoperative doxorubicin and cyclophosphamide (AC) permits more lumpectomies to be performed and decreases the incidence of positive nodes…”
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Molecular determinants of Akt-induced keratinocyte transformation by SEGRELLES, C, MORAL, M, BALLESTIN, C, PARAMIO, J. M, FERNANDA LARA, M, RUIZ, S, SANTOS, M, LEIS, H, GARCIA-ESCUDERO, R, MARTINEZ-CRUZ, A. B, MARTINEZ-PALACIO, J, HERNANDEZ, P

“…The PI3K/PTEN/Akt signaling pathway has emerged in recent years as a main player in human cancers, increasing proliferation and decreasing apoptosis of…”
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NMR metabolomics to study the metabolic response of human osteoblasts to non‐poled and poled poly (L‐lactic) acid by Araújo, Rita, Carneiro, Tatiana J., Marinho, Paula, Costa, Marisa Maltez, Roque, Ana, Cruz e Silva, Odete A. B., Fernandes, Maria Helena, Vilarinho, Paula M., Gil, Ana M.

“…Untargeted nuclear magnetic resonance (NMR) metabolomics was employed, for the first time to our knowledge, to characterize the metabolome of human osteoblast…”
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Bioinformatic analysis of the SPs and NFTs proteomes unravel putative biomarker candidates for Alzheimer's disease by Ferreira, Maria J. Cardoso, Soares Martins, Tânia, Alves, Steven R., Rosa, Ilka Martins, Vogelgsang, Jonathan, Hansen, Niels, Wiltfang, Jens, da Cruz e Silva, Odete A. B., Vitorino, Rui, Henriques, Ana Gabriela

“…Aging is the main risk factor for the appearance of age‐related neurodegenerative diseases, including Alzheimer's disease (AD). AD is the most common form of…”
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Randomized trial of postoperative Adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum : National Surgical Adjuvant breast and Bowel Project Protocol R-02 by WOLMARK, N, WIEAND, H. S, PETRELLI, N. J, DEUTSCH, M, MAMOUNAS, E, WICKERHAM, D. L, FISHER, E. R, ROCKETTE, H, FISHER, B, HYAMS, D. M, COLANGELONI KOLAY, L, DIMITROV, V, ROMOND, E. H, WEXLER, M, PRAGER, D, CRUZ, A. B, GORDON, P. H

“…The conviction that postoperative radiotherapy and chemotherapy represent an acceptable standard of care for patients with Dukes' B (stage II) and Dukes' C…”
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Analysis of the amyloid precursor protein role in neuritogenesis reveals a biphasic SH‐SY5Y neuronal cell differentiation model by Rocha, Joana Fernandes, Cruz e Silva, Odete A. B., Vieira, Sandra Isabel

“…The existence of an intrinsic programme controlling neuritogenesis and activated during early neuronal differentiation and regeneration stages is well…”
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Fourier-Transform Infrared Spectroscopy as a Discriminatory Tool for Myotonic Dystrophy Type 1 Metabolism: A Pilot Study by Mateus, Tiago, Almeida, Idália, Costa, Adriana, Viegas, Diana, Magalhães, Sandra, Martins, Filipa, Herdeiro, Maria Teresa, da Cruz E Silva, Odete A B, Fraga, Carla, Alves, Ivânia, Nunes, Alexandra, Rebelo, Sandra

“…Myotonic dystrophy type 1 (DM1) is a hereditary disease characterized by progressive distal muscle weakness and myotonia. Patients with DM1 have abnormal lipid…”
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