Search Results - "Crump, Kenny"

The Potential Effects of Recall Bias and Selection Bias on the Epidemiological Evidence for the Carcinogenicity of Glyphosate by Crump, Kenny

“…Glyphosate is a widely used herbicide worldwide. The International Agency for Research on Cancer in 2015 declared that glyphosate is probably carcinogenic to…”
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Cancer Risk Assessment and the Biostatistical Revolution of the 1970s—A Reflection by Crump, Kenny

“…Before around 1960, assessment of risk from exposure to toxic substances, including risk of cancer, was generally implemented using the NOAEL-safety factor…”
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Bogen's Critique of Linear‐No‐Threshold Default Assumptions by Crump, Kenny S.

“…In an article recently published in this journal, Bogen(1) concluded that an NRC committee's recommendations that default linear, nonthreshold (LNT)…”
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Accounting for Multiple Comparisons in Statistical Analysis of the Extensive Bioassay Data on Glyphosate by Crump, Kenny, Crouch, Edmund, Zelterman, Daniel, Crump, Casey, Haseman, Joseph

“…Abstract Glyphosate is a widely used herbicide worldwide. In 2015, the International Agency for Research on Cancer (IARC) reviewed glyphosate cancer bioassays…”
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Use of threshold and mode of action in risk assessment by Crump, Kenny S.

“…Under current guidelines, exposure guidelines for toxicants are determined by following one of two different tracks depending on whether the toxicant's mode of…”
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A Meta-Analysis of Asbestos-Related Cancer Risk That Addresses Fiber Size and Mineral Type by Berman, D. Wayne, Crump, Kenny S.

“…Quantitative estimates of the risk of lung cancer or mesothelioma in humans from asbestos exposure made by the U.S. Environmental Protection Agency (EPA) make…”
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Update of Potency Factors for Asbestos-Related Lung Cancer and Mesothelioma by Berman, D. Wayne, Crump, Kenny S.

“…The most recent update of the U.S. Environmental Protection Agency (EPA) health assessment document for asbestos (Nicholson, 1986, referred to as "the EPA 1986…”
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IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs) by MacGregor, James T., Frötschl, Roland, White, Paul A., Crump, Kenny S., Eastmond, David A., Fukushima, Shoji, Guérard, Melanie, Hayashi, Makoto, Soeteman-Hernández, Lya G., Kasamatsu, Toshio, Levy, Dan D., Morita, Takeshi, Müller, Lutz, Schoeny, Rita, Schuler, Maik J., Thybaud, Véronique, Johnson, George E.

“…•An international working group report is presented.•Recommendations for quantitative assessment of genotoxic risk are summarized.•Methods of exposure–response…”
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Influence of Alternative Exposure Estimates in the Diesel Exhaust Miners Study: Diesel Exhaust and Lung Cancer by Crump, Kenny S., Van Landingham, Cynthia, McClellan, Roger O.

“…The landmark Diesel Exhaust in Miners Study (DEMS) studied the relationship between diesel exhaust exposure (DEE) and lung cancer mortality of workers at eight…”
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Reanalysis of the DEMS Nested Case-Control Study of Lung Cancer and Diesel Exhaust: Suitability for Quantitative Risk Assessment by Crump, Kenny S., Van Landingham, Cynthia, Moolgavkar, Suresh H., McClellan, Roger

“…The International Agency for Research on Cancer (IARC) in 2012 upgraded its hazard characterization of diesel engine exhaust (DEE) to “carcinogenic to humans.”…”
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Reanalysis of Diesel Engine Exhaust and Lung Cancer Mortality in the Diesel Exhaust in Miners Study Cohort Using Alternative Exposure Estimates and Radon Adjustment by Chang, Ellen T, Lau, Edmund C, Van Landingham, Cynthia, Crump, Kenny S, McClellan, Roger O, Moolgavkar, Suresh H

“…Abstract The Diesel Exhaust in Miners Study (DEMS) (United States, 1947–1997) reported positive associations between diesel engine exhaust exposure, estimated…”
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RE: “DIESEL EXHAUST AND LUNG CANCER—AFTERMATH OF BECOMING AN IARC GROUP 1 CARCINOGEN” by Chang, Ellen T, Lau, Edmund C, Van Landingham, Cynthia, Crump, Kenny S, McClellan, Roger O, Moolgavkar, Suresh H

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Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers by Proctor, Deborah M, Suh, Mina, Mittal, Liz, Hirsch, Shawn, Valdes Salgado, Raydel, Bartlett, Chris, Van Landingham, Cynthia, Rohr, Annette, Crump, Kenny

“…The exposure-response for hexavalent chromium (Cr(VI))-induced lung cancer among workers of the Painesville Ohio chromate production facility has been used…”
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CHANG ET AL. REPLY by Chang, Ellen T, Lau, Edmund C, Van Landingham, Cynthia, Crump, Kenny S, McClellan, Roger O, Moolgavkar, Suresh H

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The Future Use of in Vitro Data in Risk Assessment to Set Human Exposure Standards: Challenging Problems and Familiar Solutions by Crump, Kenny S., Chen, Chao, Louis, Thomas A.

“…Background: The vision of a National Research Council (NRC) committee (the Committee on Toxicity Testing and Assessment of Environmental Agents) for future…”
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Diesel Engine Exhaust and Lung Cancer Mortality: Time-Related Factors in Exposure and Risk by Moolgavkar, Suresh H., Chang, Ellen T., Luebeck, Georg, Lau, Edmund C., Watson, Heather N., Crump, Kenny S., Boffetta, Paolo, McClellan, Roger

“…To develop a quantitative exposure‐response relationship between concentrations and durations of inhaled diesel engine exhaust (DEE) and increases in lung…”
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Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter by Tonacchera, Massimo, Pinchera, Aldo, Dimida, Antonio, Ferrarini, Eleonora, Agretti, Patrizia, Vitti, Paolo, Santini, Ferruccio, Crump, Kenny, Gibbs, John

“…The presence of perchlorate (ClO(4) (-)) in some U.S. drinking water supplies has raised concern about potential adverse thyroidal health effects, because…”
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Copper and Human Health: Biochemistry, Genetics, and Strategies for Modeling Dose-response Relationships by Stern, Bonnie Ransom, Solioz, Marc, Krewski, Daniel, Aggett, Peter, Aw, Tar-Ching, Baker, Scott, Crump, Kenny, Dourson, Michael, Haber, Lynne, Hertzberg, Rick, Keen, Carl, Meek, Bette, Rudenko, Larisa, Schoeny, Rita, Slob, Wout, Starr, Tom

“…Copper (Cu) and its alloys are used extensively in domestic and industrial applications. Cu is also an essential element in mammalian nutrition. Since both…”
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A statistical reevaluation of the data used in the Lanphear et al. (2005) pooled-analysis that related low levels of blood lead to intellectual deficits in children by Crump, Kenny S., Van Landingham, Cynthia, Bowers, Teresa S., Cahoy, Dexter, Chandalia, Juhi K.

“…Abstract A pooled-analysis by Lanphear et al. (2005) of seven cohort studies of the association between blood lead (BPb) concentrations in children and…”
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What Role for Biologically Based Dose—Response Models in Estimating Low-Dose Risk? by Crump, Kenny S., Chen, Chao, Chiu, Weihsueh A., Louis, Thomas A., Portier, Christopher J., Subramaniam, Ravi P., White, Paul D.

“…Background: Biologically based dose—response (BBDR) models can incorporate data on biological processes at the cellular and molecular level to link external…”
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