Search Results - "Cruden, Nicholas"

18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial by Joshi, Nikhil V, Vesey, Alex T, Williams, Michelle C, Shah, Anoop S V, Calvert, Patrick A, Craighead, Felicity H M, Yeoh, Su Ern, Wallace, William, Salter, Donald, Fletcher, Alison M, van Beek, Edwin J R, Flapan, Andrew D, Uren, Neal G, Behan, Miles W H, Cruden, Nicholas L M, Mills, Nicholas L, Fox, Keith A A, Rudd, James H F, Dweck, Marc R, Newby, David E

“…The use of non-invasive imaging to identify ruptured or high-risk coronary atherosclerotic plaques would represent a major clinical advance for prevention and…”
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Incidence, Microbiology, and Outcomes in Patients Hospitalized With Infective Endocarditis by Shah, Anoop S.V., McAllister, David A., Gallacher, Peter, Astengo, Federica, Rodríguez Pérez, Jesús Alberto, Hall, Jennifer, Ken Lee, Kuan, Bing, Rong, Anand, Atul, Nathwani, Dilip, Mills, Nicholas L., Newby, David E., Marwick, Charis, Cruden, Nicholas L.

“…BACKGROUND:Despite improvements in management, infective endocarditis remains associated with high mortality and morbidity. We describe temporal changes in the…”
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Previous Coronary Stent Implantation and Cardiac Events in Patients Undergoing Noncardiac Surgery by Cruden, Nicholas L.M, Harding, Scott A, Flapan, Andrew D, Graham, Cat, Wild, Sarah H, Slack, Rachel, Pell, Jill P, Newby, David E

“…BACKGROUND—Noncardiac surgery performed after coronary stent implantation is associated with an increased risk of stent thrombosis, myocardial infarction, and…”
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Vascular Effects of Apelin In Vivo in Man by Japp, Alan G., MRCP, Cruden, Nicholas L., PhD, Amer, David A.B, Li, Vivienne K.Y., BSc, Goudie, Ewan B., BSc, Johnston, Neil R., MSc, Sharma, Sushma, PhD, Neilson, Ilene, BSc, Webb, David J., MD, FRCP, Megson, Ian L., PhD, Flapan, Andrew D., MD, MRCP, Newby, David E., PhD, FRCP

“…Vascular Effects of Apelin In Vivo in Man Alan G. Japp, Nicholas L. Cruden, David A. B. Amer, Vivienne K. Y. Li, Ewan B. Goudie, Neil R. Johnston, Sushma…”
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Native Aortic Valve Disease Progression and Bioprosthetic Valve Degeneration in Patients With Transcatheter Aortic Valve Implantation by Kwiecinski, Jacek, Tzolos, Evangelos, Cartlidge, Timothy R.G., Fletcher, Alexander, Doris, Mhairi K., Bing, Rong, Tarkin, Jason M., Seidman, Michael A., Gulsin, Gaurav S., Cruden, Nicholas L., Barton, Anna K., Uren, Neal G., Williams, Michelle C., van Beek, Edwin J.R., Leipsic, Jonathon, Dey, Damini, Makkar, Raj R., Slomka, Piotr J., Rudd, James H.F., Newby, David E., Sellers, Stephanie L., Berman, Daniel S., Dweck, Marc R.

“…Major uncertainties remain regarding disease activity within the retained native aortic valve, and regarding bioprosthetic valve durability, after…”
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Novel cardioprotective and regenerative therapies in acute myocardial infarction: a review of recent and ongoing clinical trials by Spath, Nicholas B, Mills, Nicholas L, Cruden, Nicholas L

“…Following the original large-scale randomized trials of aspirin and β-blockade, there have been a number of major advances in pharmacological and mechanical…”
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Clopidogrel loading dose and bleeding outcomes in patients undergoing urgent coronary artery bypass grafting by Cruden, Nicholas L.M., PhD, MBChB, MRCP, Morch, Kristin, Wong, Daniel R., MD, MPH, FRCSC, Klinke, W. Peter, MD, FRCPC, Ofiesh, John, MD, FRCSC, Hilton, J. David, MD, FRCPC

“…Background Coronary artery bypass grafting (CABG) performed within 5 days of clopidogrel administration is associated with increased bleeding. The impact of…”
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Cardiovascular effects of tumour necrosis factor α antagonism in patients with acute myocardial infarction: a first in human study by Padfield, Gareth J, Din, Jehangir N, Koushiappi, Elena, Mills, Nicholas L, Robinson, Simon D, Cruden, Nicholas Le May, Lucking, Andrew John, Chia, Stanley, Harding, Scott A, Newby, David E

“…The inflammatory cytokine, tumour necrosis factor α (TNF-α), exerts deleterious cardiovascular effects. We wished to determine the effects of TNF-α antagonism…”
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Left Ventricular Thrombus After Primary PCI for ST-Elevation Myocardial Infarction: 1-Year Clinical Outcomes by Moss, Alastair J., Shah, Anoop S.V., Zuling, Eunice T., Freeman, Michael, Newby, David E., Adamson, Philip D., Cruden, Nicholas L.

“…Left ventricular thrombus formation is a complication of acute myocardial infarction. However, the incidence and risk of systemic thromboembolism in the era of…”
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Infective Endocarditis Hospitalizations and Outcomes in Patients With End-Stage Kidney Disease: A Nationwide Data-Linkage Study by Gallacher, Peter J, McAllister, David A, Mills, Nicholas L, Cruden, Nicholas L, Shah, Anoop S V, Dhaun, Neeraj

“…Background We investigated the clinical features, microbiology, and short- and long-term outcomes of incident infective endocarditis (IE) hospitalizations in…”
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Sustained cardiovascular actions of APJ agonism during renin-angiotensin system activation and in patients with heart failure by Barnes, Gareth D, Alam, Shirjel, Carter, Gordon, Pedersen, Christian M, Lee, Kristina M, Hubbard, Thomas J, Veitch, Scott, Jeong, Herim, White, Audrey, Cruden, Nicholas L, Huson, Les, Japp, Alan G, Newby, David E

“…To assess cardiovascular actions of APJ agonism during prolonged (Pyr(1))apelin-13 infusion and renin-angiotensin system activation. Forty-eight volunteers and…”
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Premature coronary artery disease and arterial stiffness: too soon to speculate? by Cruden, Nicholas L

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Progressive breathlessness following transcatheter aortic valve replacement by Andrews, Jack P M, Cruden, Nicholas L, Moss, Alastair J

“…: An 84-year-old man presented urgently to the cardiology clinic with rapid onset exertional dyspnoea while walking on the flat. Five months previously, he…”
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Recycling Between Cortisol and Cortisone in Human Splanchnic, Subcutaneous Adipose, and Skeletal Muscle Tissues In Vivo by HUGHES, Katherine A, MANOLOPOULOS, Konstantinos N, IQBAL, Javaid, CRUDEN, Nicholas L, STIMSON, Roland H, REYNOLDS, Rebecca M, NEWBY, David E, ANDREW, Ruth, KARPE, Fredrik, WALKER, Brian R

“…11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome because it catalyses reductase regeneration of cortisol from…”
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Myocardial infarction associated with patent foramen ovale and paradoxical embolism: A case series by Neisius, Ulf, Northridge, David B, Cruden, Nicholas L, Denvir, Martin A

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Vascular injury and repair: a potential target for cell therapies by Mitchell, Andrew, Fujisawa, Takeshi, Newby, David, Mills, Nicholas, Cruden, Nicholas L

“…Whether due to atherosclerotic disease or mechanical intervention, vascular injury is a frequently encountered pathology in cardiovascular medicine. The past…”
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Reduced vascular complications and length of stay with transradial rescue angioplasty for acute myocardial infarction by Cruden, Nicholas L.M., Teh, Chun H., Starkey, Ian R., Newby, David E.

“…Objectives: The aim of this study was to compare clinical outcomes for transradial and transfemoral percutaneous coronary intervention in patients with…”
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The challenge of co-existent moderate aortic stenosis and left ventricular systolic impairment by Everett, Russell J, Dweck, Marc R, Cruden, Nicholas L M

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Endothelial Progenitor Cell Biology and Vascular Recovery Following Transradial Cardiac Catheterization by Mitchell, Andrew, Fujisawa, Takeshi, Mills, Nicholas L., Brittan, Mairi, Newby, David E., Cruden, Nicholas L. M.

“…Background Transradial catheterization is associated with radial artery injury and vasomotor dysfunction and represents an accessible model of acute vascular…”
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Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury by Pedersen, Christian M., Venkatasubramanian, Sowmya, Vase, Henrik, Hyldebrandt, Janus A., Contractor, Hussain, Schmidt, Michael R., Bøtker, Hans Erik, Cruden, Nicholas L., Newby, David E., Kharbanda, Rajesh K., Lang, Ninian N.

“…Aim Ischaemia‐reperfusion injury (IRI) causes impaired endothelial function and is a major component of the adverse effects of reperfusion following myocardial…”
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