Search Results - "Crucianelli, M."

Advances in the synthesis of bioactive unnatural amino acids and peptides by Saladino, R, Botta, G, Crucianelli, M

“…The key role of proteins and amino acids in the structure and function of living matter has stimulated extensive studies. Modified amino acids with enhanced…”
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Current advances in anti-influenza therapy by Saladino, R, Barontini, M, Crucianelli, M, Nencioni, L, Sgarbanti, R, Palamara, A T

“…Every year, influenza epidemics cause numerous deaths and millions of hospitalizations, but the most frightening effects are seen when new strains of the virus…”
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Hybrid polyphenolic Network/SPIONs aggregates with potential synergistic effects in MRI applications by Lazzarini, A., Colaiezzi, R., Galante, A., Passacantando, M., Capista, D., Ferella, F., Alecci, M., Crucianelli, M.

“…[Display omitted] •We established two procedures to stably suspend SPIONs in physiological conditions.•Gd has been successfully loaded, with different ratios,…”
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First Synthesis of Totally Orthogonal Protected α-(Trifluoromethyl)- and α-(Difluoromethyl)arginines by Moroni, Maurizio, Koksch, Beate, Osipov, Sergey N, Crucianelli, Marcello, Frigerio, Massimo, Bravo, Pierfrancesco, Burger, Klaus

“…The first synthesis of a series of totally orthogonal protected racemic α-(trifluoromethyl)- and α-(difluoromethyl)arginines is described. The key steps of the…”
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Investigation of physico-chemical and catalytic properties of the coating layer of silica-coated iron oxide magnetic nanoparticles by Lazzarini, A., Colaiezzi, R., Passacantando, M., D'Orazio, F., Arrizza, L., Ferella, F., Crucianelli, M.

“…Silica-coated iron oxide magnetic nanoparticles to be employed as the starting core for easily-recoverable heterogeneous catalysts supports, were synthesized…”
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Synthesis and α1-antagonist activity of new prazosin- and benextramine-related tetraamine disulfides by GIARDINA, D, CRUCIANELLI, M, GULINI, U, MARUCCI, G, MELCHIORRE, C, SPAMPINATO, S

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(1S,RS)-6,7-Dimethoxy-N-methyl-1-(p-tolylsulfinylmethyl)-1-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline by Bravo, P., Corradi, E., Crucianelli, M., Meille, S. V., Zanda, M.

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Highly efficient C–H insertion reactions of hydrogen peroxide catalyzed by homogeneous and heterogeneous methyltrioxorhenium systems in ionic liquids by Bianchini, Gianluca, Crucianelli, Marcello, Angelis, Francesco De, Neri, Veronica, Saladino, Raffaele

“…[Display omitted] A convenient and efficient C–H insertion reaction of environment friendly H 2O 2 into representative hydrocarbon derivatives by homogeneous…”
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A novel and efficient catalytic epoxidation of olefins with adducts derived from methyltrioxorhenium and chiral aliphatic amines by Vezzosi, Stefano, Guimerais Ferré, Anna, Crucianelli, Marcello, Crestini, Claudia, Saladino, Raffaele

“…Nitrogen-based adducts derived from methyltrioxorhenium(VII) and chiral aliphatic amines have been synthesized and applied to the efficient catalytic…”
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Platinum-Based Antitumor Drugs Containing Enantiomerically Pure α-Trifluoromethyl Alanine as Ligand by Margiotta, Nicola, Papadia, Paride, Lazzaro, Francesco, Crucianelli, Marcello, De Angelis, Francesco, Pisano, Claudio, Vesci, Loredana, Natile, Giovanni

“…Synthetic amino acids such as fluorinated α-amino acids are currently actively investigated for their biological activity. Herein, we report on the synthesis…”
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Sulfinimines of trifluoropyruvate: Novel intermediates for chiral non racemic α-trifluoromethyl α-amino acids by Bravo, Pierfrancesco, Crucianelli, Marcello, Vergani, Barbara, Zanda, Matteo

“…A new and preparatively useful method for the synthesis of non racemic α-trifluoromethyl (Tfm) α-amino acids (AAs) is presented. Key-building blocks are the…”
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A novel catalyzed C–H insertion reactions of hydrogen peroxide by poly(4-vinylpyridine)/methyltrioxorhenium systems by Bianchini, Gianluca, Crucianelli, Marcello, De Angelis, Francesco, Neri, Veronica, Saladino, Raffaele

“…Graphic Novel poly(4-vinylpyridine) supported MTO compounds were effective heterogeneous catalysts for the C–H insertion reactions of H 2O 2 into some…”
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Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8 by Bianchini, Gianluca, Aschi, Massimiliano, Cavicchio, Giancarlo, Crucianelli, Marcello, Preziuso, Serena, Gallina, Carlo, Nastari, Adele, Gavuzzo, Enrico, Mazza, Fernando

“…[Display omitted] Three novel peptidomimetic phosphinate inhibitors have been synthesized and evaluated as inhibitors of matrix metalloproteinases MMP-2 and…”
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A novel oxidative side-chain transformation of α-amino acids and peptides by methyltrioxorhenium/H2O2 system by Lazzaro, Francesco, Crucianelli, Marcello, De Angelis, Francesco, Neri, Veronica, Saladino, Raffaele

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Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2 by Agamennone, Mariangela, Campestre, Cristina, Preziuso, Serena, Consalvi, Valerio, Crucianelli, Marcello, Mazza, Fernando, Politi, Vincenzo, Ragno, Rino, Tortorella, Paolo, Gallina, Carlo

“…The phosphotryptophan derivative l-Pro- l-Leu- l-(P)Trp(OH) 2 ( 2b) was reported as the first example of left-hand-side 1 1 Left-hand-side inhibitors:…”
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Stereoselective synthesis of ( R)- and ( S)-α-trifluoromethyl aspartic acid via titanium enolate addition to a sulfinimine of trifluoropyruvate by Lazzaro, Francesco, Crucianelli, Marcello, De Angelis, Francesco, Frigerio, Massimo, Malpezzi, Luciana, Volonterio, Alessandro, Zanda, Matteo

“…Graphic The reaction of an enantiomerically pure sulfinimine of trifluoropyruvate with several metal enolates is described. The use of TiCl(O- iPr) 3/LDA…”
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The "Non-Oxidative" pummerer reaction: conclusive evidence for S(N)2-type stereoselectivity, mechanistic insight, and synthesis of enantiopure L-alpha-trifluoromethylthreoninate and D-alpha-trifluoromethyl-allo-threoninate(1) by Crucianelli, M, Bravo, P, Arnone, A, Corradi, E, Meille, SV, Zanda, M

“…Enantiopure methyl D-alpha-trifluoromethyl-allo-threoninate 18 and L-alpha-trifluoromethylthreoninate 19 were synthesized using (R)-ethyl p-tolylsulfoxide as…”
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Synthesis of enantiomerically pure α-ethyl, α-vinyl and α-ethynyl 3,3,3-trifluoro alaninates by Crucianelli, Marcello, Angelis, Francesco De, Lazzaro, Francesco, Malpezzi, Luciana, Volonterio, Alessandro, Zanda, Matteo

“…Graphic We describe the first synthesis of enantiomerically pure ( S)-α-vinyl and ( S)-α-ethynyl 3,3,3-trifluoro alanine (TF-Ala) ethyl esters, starting from…”
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Synthesis of Nonracemic α-Trifluoromethyl α-Amino Acids from Sulfinimines of Trifluoropyruvate by Asensio, Amparo, Bravo, Pierfrancesco, Crucianelli, Marcello, Farina, Alessandra, Fustero, Santos, Soler, Juan García, Meille, Stefano V., Panzeri, Walter, Viani, Fiorenza, Volonterio, Alessandro, Zanda, Matteo

“…We describe a novel and useful method for the synthesis of nonracemic α‐trifluoromethyl α‐amino acids (α‐Tfm‐AAs). Key building blocks are the sulfinimines…”
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Synthesis and biological activity of β-fluoroalkyl β-amino alcohols by Bravo, Pierfrancesco, Crucianelli, Marcello, Ono, Taizo, Zanda, Matteo

“…This paper reviews the synthesis of unnatural chiral β-fluoroalkyl β-amino alcohols, with an emphasis on their biological activity and pharmaceutical…”
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