Search Results - "Cruchley, A."

Characterizing the immunological effects of oral healthcare ingredients using an in vitro reconstructed human epithelial model by Hagi-Pavli, E., Williams, D.M., Rowland, J.L., Thornhill, M., Cruchley, A.T.

“…•Differential response of oral mucosal model to irritant and sensitizer compounds.•Shown irritants induce significant IL-1α in oral epithelial…”
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Porphyromonas gingivalis culture supernatants differentially regulate Interleukin-1β and Interleukin-18 in human monocytic cells by Hamedi, M., Belibasakis, G.N., Cruchley, A.T., Rangarajan, M., Curtis, M.A., Bostanci, N.

“…Porphyromonas gingivalis is a major bacterial species implicated in chornic periodontitis, a disease characterized by inflammatory destruction of the tooth…”
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Recombinant human bone morphogenetic protein-2 promotes wound healing in rat periodontal fenestration defects by King, G N, King, N, Cruchley, A T, Wozney, J M, Hughes, F J

“…Although there is considerable interest in the use of bone morphogenetic protein (BMP) to promote periodontal regeneration, little is known of its effects on…”
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Short-term exposure to alcohol increases the permeability of human oral mucosa by Howie, NM, Trigkas, TK, Cruchley, AT, Wertz, PW, Squier, CA, Williams, DM

“…OBJECTIVES: The aim of this study was to evaluate the effect of short‐term exposure to ethanol on the permeability barrier properties of human oral mucosa…”
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A polymeric system for the intra-oral delivery of an anti-fungal agent by Patel, M.P, Cruchley, A.T, Coleman, D.C, Swai, H, Braden, M, Williams, D.M

“…Oral candidal infections are often persistent and intractable and thus the aim of this study was to develop a polymeric sustained release device to improve the…”
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Vascular endothelial growth factor in human periodontal disease by Booth, V., Young, S., Cruchley, A., Taichman, N. S., Paleolog, E.

“…Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic cytokine of importance in inflammation and wound healing but its presence in chronic…”
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Human neutrophils secrete vascular endothelial growth factor by Taichman, Norton S., Young, Sylvia, Cruchley, Alan T., Taylor, Peter, Paleolog, Ewa

“…Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that plays a pivotal role in mediating neovascularization as well as other endothelial…”
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Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro by HOU, L., KAPAS, S., CRUCHLEY, A. T., MACEY, M. G., HARRIOTT, P., CHINNI, C., STONE, S. R., HOWELLS, G. L.

“…The protease‐activated receptor‐2 (PAR‐2) is a seven transmembrane domain receptor related to the thrombin receptor, which is activated in vitro by cleavage by…”
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Expression of Adrenomedullin and its Receptors in Human Salivary Tissue by Kapas, S., Pahal, K., Cruchley, A.T., Hagi-Pavli, E., Hinson, J.P.

“…Adrenomedullin is a multifunctional peptide produced by a wide range of different cells and tissues. This study was designed to investigate whether…”
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Fingerprinting genomic instability in oral submucous fibrosis by Teh, M. T., Tilakaratne, W. M., Chaplin, T., Young, B. D., Ariyawardana, A., Pitiyage, G., Lalli, A., Stewart, J. E., Hagi-Pavli, E., Cruchley, A., Waseem, A., Fortune, F.

“…Background:  Oral submucous fibrosis (OSF) is a high‐risk pre‐cancerous condition where 7–13% of these patients develop head and neck squamous cell carcinoma…”
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Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo by CICALA, C, PINTO, A, BUCCI, M, SORRENTINO, R, WALKER, B, HARRIOT, P, CRUCHLEY, A, KAPAS, S, HOWELLS, G. L, CIRINO, G

“…The protease-activated receptor-2 (PAR-2) is expressed by vascular endothelial cells and upregulated by lipopolysaccharide (LPS) in vitro. PAR-2 is activated…”
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Vascular endothelial growth factor in normal human salivary glands and saliva: a possible role in the maintenance of mucosal homeostasis by Taichman, N S, Cruchley, A T, Fletcher, L M, Hagi-Pavli, E P, Paleolog, E M, Abrams, W R, Booth, V, Edwards, R M, Malamud, D

“…Saliva is an enriched milieu containing biologically active proteins, including several different growth factors and cytokines. This study documents that…”
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The permeability of human oral mucosa and skin to water by Lesch, C A, Squier, C A, Cruchley, A, Williams, D M, Speight, P

“…Specimens from four regions of oral mucosa (palate, buccal mucosa, lateral border of the tongue, and the floor of the mouth) and of abdominal skin were taken…”
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Release of recombinant human bone morphogenetic protein-2 from heterocyclic methacrylate polymer systems by Patel, M.P, Pavlovic, P, Hughes, F.J, King, G.N, Cruchley, A, Braden, M

“…The release of recombinant human bone morphogenetic protein-2 (rhBMP-2) from three room temperature polymerising methacrylate systems has been studied. These…”
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Immunocytochemical investigation of the rat cementoblast phenotype by Tenorio, D, Cruchley, A, Hughes, F J

“…Recent studies have suggested that cementoblasts may be derived from osteoblast progenitor cells, although the cementoblast phenotype has not been extensively…”
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Porphyromonas gingivalis culture supernatants differentially regulate interleukin-1beta and interleukin-18 in human monocytic cells by Hamedi, M, Belibasakis, G N, Cruchley, A T, Rangarajan, M, Curtis, M A, Bostanci, N

“…Porphyromonas gingivalis is a major bacterial species implicated in chornic periodontitis, a disease characterized by inflammatory destruction of the tooth…”
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Ki-67 antigen in ameloblastomas: correlation with clinical and histological parameters in 54 cases from Kenya by Ong'uti, Meshach N., Cruchley, Alan T., Howells, Gareth L., Williams, David M.

“…The aim of this study was to assess the cell proliferation in ameloblastomas and to correlate this with clinical features and histology. Immunohistochemistry…”
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The effect of sodium lauryl sulphate, triclosan and zinc on the permeability of normal oral mucosa by Healy, CM, Cruchley, AT, Thornhill, MH, Williams, DM

“…OBJECTIVE: Sodium lauryl sulphate (SLS), an important component in many oral health products, is well established as a contact irritant in skin. Recent studies…”
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Epstein-Barr virus: Biology and disease by Cruchley, AT, Williams, DM, Niedobitek, G, Young, LS

“…Epstein—Barr virus is a human herpes virus which, whilst found as a widespread asymptomatic infection, is also associated with certain tumours of lymphoid and…”
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The activation of Langerhans cells in oral lichen planus by Farthing, P M, Matear, P, Cruchley, A T

“…The numbers of CD1, HLADR, HLADP and HLADQ positive, intraepithelial, dendritic cells were compared in lesions of oral lichen planus and normal oral mucosa…”
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