Search Results - "Crüger, D."

Breast cancer after bilateral risk-reducing mastectomy by Skytte, A-B, Crüger, D, Gerster, M, Lænkholm, A-V, Lang, C, Brøndum-Nielsen, K, Andersen, MK, Sunde, L, Kølvraa, S, Gerdes, A-M

“…Skytte A‐B, Crüger D, Gerster M, Lænkholm A‐V, Lang C, Brøndum‐Nielsen K, Andersen MK, Sunde L, Kølvraa S, Gerdes A‐M. Breast cancer after bilateral…”
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The importance of KRAS mutations and EGF61A>G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer by Garm Spindler, K. -L., Pallisgaard, N., Rasmussen, A.A., Lindebjerg, J., Andersen, R.F., Crüger, D., Jakobsen, A.

“…The effect of anti-epidermal growth factor receptor (EGFR) antibodies (mAb) in metastatic colorectal cancer seems limited to KRAS wild-type (wt) tumours, but…”
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Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing by Skytte, A-B, Gerdes, A-M, Andersen, MK, Sunde, L, Brøndum-Nielsen, K, Waldstrøm, M, Kølvraa, S, Crüger, D

“…Skytte A‐B, Gerdes A‐M, Andersen MK, Sunde L, Brøndum‐Nielsen K, Waldstrøm M, Kølvraa S, Crüger D. Risk‐reducing mastectomy and salpingo‐oophorectomy in…”
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Sequential FISH analysis using competitive displacement of labelled peptide nucleic acid probes for eight chromosomes in human blastomeres by Agerholm, I.E., Ziebe, S., Williams, B., Berg, C., Crüger, D.G., Petersen, G. Bruun, Kølvraa, S.

“…BACKGROUND: The aim was to introduce a new strategy based on peptide nucleic acid (PNA) probes and competitive displacement for using fluorescence in-situ…”
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Annual surveillance by CA125 and transvaginal ultrasound for ovarian cancer in both high‐risk and population risk women is ineffective by Woodward, ER, Sleightholme, HV, Considine, AM, Williamson, S, McHugo, JM, Cruger, DG

“…Objective  To assess the efficacy of annual CA125 and transvaginal ultrasound (TVU) scan as surveillance for ovarian cancer. Design  Retrospective audit…”
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Birth of a healthy girl after ICSI with ejaculated spermatozoa from a man with non-mosaic Klinefelter's syndrome: Case report by Crüger, D., Toft, B., Agerholm, I., Fedder, J., Hald, F., Bruun-Petersen, G.

“…Klinefelter's syndrome is a major contributor to male infertility. Recent reports of births after ICSI with especially testicular spermatozoa from infertile…”
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Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study by Mitra, Anita V., Bancroft, Elizabeth K., Barbachano, Yolanda, Page, Elizabeth C., Foster, C. S., Jameson, C., Mitchell, G., Lindeman, G. J., Stapleton, A., Suthers, G., Evans, D. G., Cruger, D., Blanco, I., Mercer, C., Kirk, J., Maehle, L., Hodgson, S., Walker, L., Izatt, L., Douglas, F., Tucker, K., Dorkins, H., Clowes, V., Male, A., Donaldson, A., Brewer, C., Doherty, R., Bulman, B., Osther, P. J., Salinas, M., Eccles, D., Axcrona, K., Jobson, I., Newcombe, B., Cybulski, C., Rubinstein, W. S., Buys, S., Townshend, S., Friedman, E., Domchek, S., Ramon y Cajal, T., Spigelman, A., Teo, S. H., Nicolai, N., Aaronson, N., Ardern‐Jones, A., Bangma, C., Dearnaley, D., Eyfjord, J., Falconer, A., Grönberg, H., Hamdy, F., Johannsson, O., Khoo, V., Kote‐Jarai, Z., Lilja, H., Lubinski, J., Melia, J., Moynihan, C., Peock, S., Rennert, G., Schröder, F., Sibley, P., Suri, M., Wilson, P., Bignon, Y. J., Strom, S., Tischkowitz, M., Liljegren, A., Ilencikova, D., Abele, A., Kyriacou, K., van Asperen, C., Kiemeney, L., Easton, D. F., Eeles, Rosalind A.

“…Study Type – Diagnostic (validating cohort)
Level of Evidence 1b What’s known on the subject? and What does the study add? Scientists have found a number of…”
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Strategy in clinical practice for classification of unselected colorectal tumours based on mismatch repair deficiency by Jensen, L. H., Lindebjerg, J., Byriel, L., Kolvraa, S., Crüger, D. G.

“…Objective  Deficiency of DNA mismatch repair (MMR) causes microsatellite instability (MSI) in a subset of colorectal cancers. Patients with these tumours have…”
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Fertility and pregnancy outcome in Danish women with Turner syndrome by Birkebaek, NH, Crüger, D, Hansen, J, Nielsen, J, Bruun-Petersen, G

“…The aim of the investigation was to study fertility in Danish women diagnosed with Turner syndrome (TS), and to describe their offspring. In total, 410 women…”
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EARLY PRENATAL DIAGNOSIS: STANDARD CYTOGENETIC ANALYSIS OF COELOMIC CELLS OBTAINED BY COELOCENTESIS by CRÜGER, D. G., BRUUN‐PETERSEN, G., KØLVRAA, S.

“…Coelomic fluid samples (n=30) were obtained from normal pregnancies between 6·0 and 10·0 weeks and attempts to culture the coelomic cells were made. With one…”
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Quantitative evaluation of fluorescence in situ hybridization (FISH) signals in uncultured coelomic cells by Crüger, D. G., Bruun-Petersen, G., Kølvraa, S.

“…Uncultured coelomic cells were hybridized with alpha satellite DNA probes representing chromosomes X, Y, 18, and 13/21 in order to evaluate the distribution of…”
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Evaluation of two different models to predict BRCA1 and BRCA2 mutations in a cohort of Danish hereditary breast and/or ovarian cancer families by Gerdes, A-M, Cruger, DG, Thomassen, M, Kruse, TA

“…To meet the increasing demand for BRCA1 and BRCA2 mutation analysis, a robust system for selecting families who have a higher chance of a mutation has become…”
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Nuclei size in relation to nuclear status and aneuploidy rate for 13 chromosomes in donated four cells embryos by Agerholm, I. E., Hnida, C., Crüger, D. G., Berg, C., Bruun-Petersen, G., Kølvraa, S., Ziebe, S.

“…Purpose The aim was to elucidate if the nuclear size and number are indicative of aberrant chromosome content in human blastomeres and embryos. Methods The…”
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Genetic analysis of males from intracytoplasmic sperm injection couples by Cruger, DG, Agerholm, I, Byriel, L, Fedder, J, Bruun-Petersen, G

“…A total of 392 men referred for intracytoplasmic sperm injection (ICSI) participated in genetic analysis. The control group consisted of 100 normal fertile…”
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Birth of a healthy girl after ICSI with ejaculated spermatozoa from a man with non-mosaic Klinefelter's syndrome by CRÜGER, D, TOFT, B, AGERHOLM, I, FEDDER, J, HALD, F, BRUUN-PETERSEN, G

“…Klinefelter's syndrome is a major contributor to male infertility. Recent reports of births after ICSI with especially testicular spermatozoa from infertile…”
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Selecting patients with young-onset colorectal cancer for mismatch repair gene analysis by Walker, M., O'Sullivan, B., Perakath, B., Taniere, P., Cruger, D., Morton, D.

“…Background: Young patients with colorectal cancer are at increased risk of carrying a germline mutation in mismatch repair (MMR) genes. This study investigated…”
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Identification of a group of proteins that are strongly up-regulated in total epidermal keratinocytes from psoriatic skin by Celis, Julio E., Cruger, Dorthe, Kiil, Jette, Lauridsen, Jette B., Ratz, Gitte, Basse, Bodil, Celis, Ariana

“…Analysis using two-dimensional (2D) gel electrophoresis of the [ 35S]-methionine-labelled proteins synthesized by non-cultured total epidermal keratinocytes…”
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'Indirect' BRCA1/2 testing. A useful approach in hereditary breast and ovarian cancer families without a living affected relative by Cruger, DG, Kruse, TA, Gerdes, AM

“…We report an approach for BRCA1/2 testing whereby genetic testing can be offered to families at high risk of hereditary breast and ovarian cancer but where no…”
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Computerized, comprehensive databases of cellular and secreted proteins from normal human embryonic lung MRC-5 fibroblasts: identification of transformation and/or proliferation sensitive proteins by Celis, J E, Ratz, G P, Madsen, P, Gesser, B, Lauridsen, J B, Hansen, K P, Kwee, S, Rasmussen, H H, Nielsen, H V, Crüger, D

“…Databases of protein information from human embryonal lung fibroblasts (MRC-5) have been established using computer analyzed two-dimensional gel…”
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Molecular biology from bench-to-bedside: Which colorectal cancer patients to refer for genetic counseling by Jensen, L. H., Dysager, L., Lindebjerg, J., Kølvraa, S., Byriel, L., Crüger, D. G.

“…Abstract only 4113 Background: The single most common cause of hereditary colorectal cancer is the Lynch syndrome, which is associated with deficiency of the…”
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