Search Results - "Crozier, Stephen J"

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  1. 1

    Oral leucine administration stimulates protein synthesis in rat skeletal muscle by Crozier, Stephen J, Kimball, Scot R, Emmert, Sans W, Anthony, Joshua C, Jefferson, Leonard S

    Published in The Journal of nutrition (01-03-2005)
    “…Oral administration of a single bolus of leucine in an amount equivalent to the daily intake (1.35 g/kg body wt) enhances skeletal muscle protein synthesis in…”
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  2. 2

    Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle by Bolster, Douglas R., Kubica, Neil, Crozier, Stephen J., Williamson, David L., Farrell, Peter A., Kimball, Scot R., Jefferson, Leonard S.

    Published in The Journal of physiology (15-11-2003)
    “…The purpose of the present investigation was to determine whether mammalian target of rapamycin (mTOR)-mediated signalling and some key regulatory proteins of…”
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  3. 3

    Cacao seeds are a "Super Fruit": A comparative analysis of various fruit powders and products by Crozier, Stephen J, Preston, Amy G, Hurst, Jeffrey W, Payne, Mark J, Mann, Julie, Hainly, Larry, Miller, Debra L

    Published in BMC chemistry (07-02-2011)
    “…Background Numerous popular media sources have developed lists of "Super Foods" and, more recently, "Super Fruits". Such distinctions often are based on the…”
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  4. 4

    AMP-activated Protein Kinase Suppresses Protein Synthesis in Rat Skeletal Muscle through Down-regulated Mammalian Target of Rapamycin (mTOR) Signaling by Bolster, Douglas R., Crozier, Stephen J., Kimball, Scot R., Jefferson, Leonard S.

    Published in The Journal of biological chemistry (05-07-2002)
    “…AMP-activated protein kinase (AMPK) is viewed as an energy sensor that acts to modulate glucose uptake and fatty acid oxidation in skeletal muscle. Given that…”
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  5. 5

    Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine by Anthony, Joshua C, Lang, Charles H, Crozier, Stephen J, Anthony, Tracy G, MacLean, David A, Kimball, Scot R, Jefferson, Leonard S

    “…Enhanced protein synthesis in skeletal muscle after ingestion of a balanced meal in postabsorptive rats is mimicked by oral leucine administration. To assess…”
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  6. 6

    Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside by Reiter, Ali K, Bolster, Douglas R, Crozier, Stephen J, Kimball, Scot R, Jefferson, Leonard S

    “…The studies described herein were designed to investigate the effects of 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside (AICAR), an activator of the…”
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  7. 7

    Orally Administered Leucine Enhances Protein Synthesis in Skeletal Muscle of Diabetic Rats in the Absence of Increases in 4E-BP1 or S6K1 Phosphorylation by ANTHONY, Joshua C, REITER, Ali K, ANTHONY, Tracy G, CROZIER, Stephen J, LANG, Charles H, MACLEAN, David A, KIMBALL, Scot R, JEFFERSON, Leonard S

    Published in Diabetes (New York, N.Y.) (01-04-2002)
    “…Orally Administered Leucine Enhances Protein Synthesis in Skeletal Muscle of Diabetic Rats in the Absence of Increases in 4E-BP1 or S6K1 Phosphorylation Joshua…”
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  8. 8

    Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis by Kimball, Scot R, O'Malley, James P, Anthony, Joshua C, Crozier, Stephen J, Jefferson, Leonard S

    “…Loss of muscle strength is a principal factor in the development of physical frailty, a condition clinically associated with increased risk of bone fractures,…”
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  9. 9

    Molecular Mechanisms of Pancreatic Dysfunction Induced by Protein Malnutrition by Crozier, Stephen J, D'Alecy, Louis G, Ernst, Stephen A, Ginsburg, Lauren E, Williams, John A

    Published in Gastroenterology (New York, N.Y. 1943) (01-09-2009)
    “…Background & Aims Dietary protein deficiency results in diminished capacity of the pancreas to secrete enzymes needed for macronutrient digestion. Previous…”
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  10. 10

    Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice by Crozier, Stephen J., Sans, M. Dolors, Guo, LiLi, D'Alecy, Louis G., Williams, John A.

    Published in The Journal of physiology (15-06-2006)
    “…Cholecystokinin (CCK)-induced pancreatic growth in mice involves parallel increases in DNA and protein. The mammalian target of rapamycin (mTOR) signalling…”
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  11. 11

    Cellular energy status modulates translational control mechanisms in ischemic-reperfused rat hearts by Crozier, Stephen J, Vary, Thomas C, Kimball, Scot R, Jefferson, Leonard S

    “…Mechanisms regulating ischemia and reperfusion (I/R)-induced changes in mRNA translation in the heart are poorly defined, as are the factors that initiate…”
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  12. 12

    Meal feeding alters translational control of gene expression in rat liver by Reiter, Ali K, Crozier, Stephen J, Kimball, Scot R, Jefferson, Leonard S

    Published in The Journal of nutrition (01-03-2005)
    “…Meal feeding after a period of food deprivation results in a subsequent increase in the protein and RNA content of the liver. To gain insight into the…”
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  13. 13

    Dietary Protein and Amino Acid Deficiency Inhibit Pancreatic Digestive Enzyme mRNA Translation by Multiple Mechanisms by Sans, Maria Dolors, Crozier, Stephen J., Vogel, Nancy L., D’Alecy, Louis G., Williams, John A.

    “…Chronic amino acid (AA) deficiency, as in kwashiorkor, reduces the size of the pancreas through an effect on mammalian target of rapamycin complex 1 (mTORC1)…”
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  14. 14

    Regulator of Calcineurin 1 Controls Growth Plasticity of Adult Pancreas by Gurda, Grzegorz T, Crozier, Stephen J, Ji, Baoan, Ernst, Stephen A, Logsdon, Craig D, Rothermel, Beverly A, Williams, John A

    Published in Gastroenterology (New York, N.Y. 1943) (01-08-2010)
    “…Background & Aims Growth of exocrine pancreas is regulated by gastrointestinal hormones, notably cholecystokinin (CCK). CCK-driven pancreatic growth requires…”
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  15. 15

    CCK-independent mTORC1 activation during dietary protein-induced exocrine pancreas growth by Crozier, Stephen J, Sans, M Dolors, Wang, Jackie Y, Lentz, Stephen I, Ernst, Stephen A, Williams, John A

    “…Dietary protein can stimulate pancreatic growth in the absence of CCK release, but there is little data on the regulation of CCK-independent growth. To…”
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  16. 16

    CCK-induced pancreatic growth is not limited by mitogenic capacity in mice by Crozier, Stephen J, Sans, Maria Dolors, Lang, Charles H, D'Alecy, Louis G, Ernst, Stephen A, Williams, John A

    “…In mice fed trypsin inhibitor (camostat) to elevate endogenous CCK, pancreatic growth plateaus by 7 days. It is unknown whether this represents the maximum…”
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  17. 17

    Activation of signaling pathways and regulatory mechanisms of mRNA translation following myocardial ischemia-reperfusion by Crozier, Stephen J, Zhang, Xueqian, Wang, Jufang, Cheung, Joseph, Kimball, Scot R, Jefferson, Leonard S

    Published in Journal of applied physiology (1985) (01-08-2006)
    “…Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania Submitted 9 September 2005 ;…”
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  18. 18

    AMPK represses TOP mRNA translation but not global protein synthesis in liver by Reiter, Ali K., Bolster, Douglas R., Crozier, Stephen J., Kimball, Scot R., Jefferson, Leonard S.

    “…The AMP-activated protein kinase (AMPK) represses signaling through the mammalian target of rapamycin complex 1 (mTORC1). In muscle, repression of mTORC1 leads…”
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  19. 19

    Effect of Midmorning Puree Snacks on Subjective Appetite, Food Intake, and Glycemic and Insulin Responses in Healthy Adults by Guo, Qing, Totosy de Zepetnek, Julia, Chang, Jennifer, Hayden, Julia, Crozier, Stephen J., Mongia, Gagan, Rousseau, Dérick, Bellissimo, Nick

    “…Objective: Dietary pattern changes, as a part of a healthy lifestyle, may improve weight management. The objective of this study was to examine the effect of…”
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