Search Results - "Crowley, L C"

The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells by Nyhan, M J, O'Donovan, T R, Elzinga, B, Crowley, L C, O'Sullivan, G C, McKenna, S L

“…Background: Resistance to chemotherapeutic agents has been associated with a failure of cancer cells to induce apoptosis. Strategies to restore apoptosis have…”
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The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate by Crowley, C L, Payne, C M, Bernstein, H, Bernstein, C, Roe, D

“…The bile salt, sodium deoxycholate (NaDOC), is a natural detergent that promotes digestion of fats. At high physiologic levels, NaDOC activates many…”
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Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate by Bernstein, Harris, Payne, Claire M., Bernstein, Carol, Schneider, John, Beard, Shannon E., Crowley, Cara L.

“…Toxic bile salts, retained within the liver because of impaired biliary excretion, are considered to play a major role in liver injury during cholestasis. Bile…”
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Caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis: Protective role of the nitric oxide signaling module by PAYNE, C. M, WALTMIRE, C. N, CROWLEY, C, CROWLEY-WEBER, C. L, DVORAKOVA, K, BERNSTEIN, H, BERNSTEIN, C, HOLUBEC, H, GAREWAL, H

“…Hydrophobic bile acids such as deoxycholate are known tumor promoters in the gastrointestinal tract. We have previously shown that deoxycholate induces…”
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Mitochondrial perturbation attenuates bile acid-induced cytotoxicity by Payne, C M, Crowley-Weber, C L, Dvorak, K, Bernstein, C, Bernstein, H, Holubec, H, Crowley, C, Garewal, H

“…Hydrophobic bile acids such as deoxycholate (DOC) are known to damage liver cells during cholestasis and promote colon cancer. Cellular stresses induced by…”
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The NAD+Precursors, Nicotinic Acid and Nicotinamide Upregulate Glyceraldehyde-3-Phosphate Dehydrogenase and Glucose-6-Phosphate Dehydrogenase mRNA in Jurkat Cells by Yan, Qing, Briehl, Margaret, Crowley, Cara L., Payne, Claire M., Bernstein, Harris, Bernstein, Carol

“…To better understand the role of nicotinic acid and nicotinamide in the regulation of the oxidative stress response, we measured the levels of…”
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Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate by Crowley-Weber, Cara L., Payne, Claire M., Gleason-Guzman, Mary, Watts, George S., Futscher, Bernard, Waltmire, Caroline N., Crowley, Cheray, Dvorakova, Katerina, Bernstein, Carol, Craven, Mary, Garewal, Harinder, Bernstein, Harris

“…Evidence from live cell bioassays shows that the flat mucosa from patients with colon cancer exhibits resistance to bile salt-induced apoptosis. Three…”
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The BH3 mimetic HAI4-I enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells by NYHAN, M. J, O'DONOVAN, T. R, ELZINGA, B, CROWLEY, L. C, O'SULLIVAN, G. C, MCKENNA, S. L

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Adjacency externalities and forest fire prevention by Crowley, Christian S.L, Malik, Arun S, Amacher, Gregory S, Haight, Robert G

“…This paper models landowner behavior on timberland subject to damage by fire. We examine how management decisions by adjacent landowners yield outcomes that…”
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Nicotine increases oxidative stress, activates NF-κB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis by Crowley-Weber, Cara L, Dvorakova, Katerina, Crowley, Cheray, Bernstein, Harris, Bernstein, Carol, Garewal, Harinder, Payne, Claire M

“…Epidemiologic studies indicate that environmental (smoking) and dietary factors (high fat) contribute to carcinogenesis in many organ systems. The aim of our…”
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Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis by Washo-Stultz, Delon, Crowley-Weber, Cara L, Dvorakova, Katerina, Bernstein, Carol, Bernstein, Harris, Kunke, Kathleen, Waltmire, Caroline N, Garewal, Harinder, Payne, Claire M

“…Bile acids are promoters of colon cancer; however, the mechanism(s) of action of this tumor promoter are largely unknown. Bile acids induce apoptosis in colon…”
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A proteomic study of resistance to deoxycholate-induced apoptosis by Bernstein, Harris, Payne, Claire M., Kunke, Kathleen, Crowley-Weber, Cara L., Waltmire, Caroline N., Dvorakova, Katerina, Holubec, Hana, Bernstein, Carol, Vaillancourt, Richard R., Raynes, Deborah A., Guerriero, Vincent, Garewal, Harinder

“…The development of apoptosis resistance appears to be an important factor in colon carcinogenesis. To gain an understanding of the molecular pathways altered…”
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Adolescents' Perceptions of the Benefits and Risks of Their Own Risk Taking by Siegel, Alexander W., Cousins, Jennifer H., Rubovits, David S., Parsons, Jeffrey T., Lavery, Barbara, Crowley, Carolyn L.

“…Currently, there is much interest in the extent to which adolescents engage in risk-taking behavior (RTB), particularly drinking alcohol, smoking cigarettes,…”
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