Search Results - "Crowley, D."
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The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension
Published in Antioxidants & redox signaling (01-01-2014)“…Innate and adaptive immunity play fundamental roles in the development of hypertension and its complications. As effectors of the cell-mediated immune…”
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Immunologic Effects of the Renin-Angiotensin System
Published in Journal of the American Society of Nephrology (01-05-2017)“…Inappropriate activation of the renin-angiotensin system (RAS) exacerbates renal and vascular injury. Accordingly, treatment with global RAS antagonists…”
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3
Nonadiabatic Topological Energy Pumps with Quasiperiodic Driving
Published in Physical review letters (12-03-2021)“…We derive a topological classification of the steady states of d-dimensional lattice models driven by D incommensurate tones. Mapping to a unifying…”
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Salt, Hypertension, and Immunity
Published in Annual review of physiology (10-02-2018)“…The link between inappropriate salt retention in the kidney and hypertension is well recognized. However, growing evidence suggests that the immune system can…”
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Metallo‐Supramolecular Self‐Assembly with Reduced‐Symmetry Ligands
Published in ChemPlusChem (Weinheim, Germany) (01-05-2020)“…Metallo‐supramolecular self‐assembly tends to be performed with single metal ions and single, highly symmetrical, ligands. This simplifies the self‐assembly…”
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The Immune System in Hypertension: a Lost Shaker of Salt 2021 Lewis K. Dahl Memorial Lecture
Published in Hypertension (Dallas, Tex. 1979) (01-07-2022)“…The seminal observations of Dr Lewis Dahl regarding renal mechanisms of hypertension remain highly relevant in light of more recent experiments showing that…”
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A Nona‐nuclear Heterometallic Pd3Pt6 “Donut”‐Shaped Cage: Molecular Recognition and Photocatalysis
Published in Angewandte Chemie International Edition (09-07-2018)“…We report a simple, low‐symmetry 2‐(1‐(pyridine‐4‐methyl)‐1H‐1,2,3‐triazol‐4‐yl)pyridine ligand that has both monodentate and bidentate binding sites. With…”
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The role of macrophages in hypertension and its complications
Published in Pflügers Archiv (01-04-2017)“…Circulating monocytes and tissue macrophages play complex roles in the pathogenesis of hypertension, a highly prevalent disease associated with catastrophic…”
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Animal Models of Hypertension: A Scientific Statement From the American Heart Association
Published in Hypertension (Dallas, Tex. 1979) (01-06-2019)“…Hypertension is the most common chronic disease in the world, yet the precise cause of elevated blood pressure often cannot be determined. Animal models have…”
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Externalizing Psychopathology From Childhood to Early Adolescence: Psychometric Evaluation Using Latent Variable and Network Modeling
Published in Psychological assessment (01-11-2022)“…Applying both latent variable and network frameworks, we conducted a comprehensive psychometric evaluation of the diverse array of symptoms from three…”
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Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation
Published in Journal of the American Society of Nephrology (01-03-2018)“…Albuminuria is a key instigator of tubulointerstitial inflammation associated with CKD, but the mechanism through which filtered albumin propagates renal…”
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The role of social impact bonds in pediatric health care
Published in Pediatrics (Evanston) (01-08-2014)Get full text
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Can we build an efficient response to the prescription drug abuse epidemic? Assessing the cost effectiveness of universal prevention in the PROSPER trial
Published in Preventive medicine (01-05-2014)“…Abstract Purpose Prescription drug abuse has reached epidemic proportions. Nonmedical prescription opioid use carries increasingly high costs. Despite the need…”
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Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron
Published in Cell metabolism (09-02-2016)“…Hypertension is among the most prevalent and catastrophic chronic diseases worldwide. While the efficacy of renin angiotensin system (RAS) blockade in lowering…”
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Strategies for Reversible Guest Uptake and Release from Metallosupramolecular Architectures
Published in Chemistry : a European journal (09-10-2018)“…The cavities of metallosupramolecular cages can be used to mimic the central spaces of naturally occurring proteins and bind a wide variety of molecular…”
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Clotrimazole as a pharmaceutical: past, present and future
Published in Journal of applied microbiology (01-09-2014)“…Clotrimazole is a broad‐spectrum antimycotic drug mainly used for the treatment of Candida albicans and other fungal infections. A synthetic, azole…”
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Legislating to Prevent Adverse Childhood Experiences: Growth and Opportunities for Evidence-Based Policymaking and Prevention
Published in Prevention science (01-02-2022)“…Since the landmark study of Adverse Childhood Experiences (ACEs; Felitti et al., American Journal of Preventive Medicine, 14(4):245–258, 1998 ), there has been…”
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Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation
Published in Cell death & disease (02-03-2018)“…Inflammation is a major contributor to the pathogenesis of ischemic acute kidney injury (AKI), which complicates the post-operative outcomes of large numbers…”
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Multicavity Metallosupramolecular Architectures
Published in Chemistry, an Asian journal (05-10-2017)“…Discrete metallosupramolecular systems are often macrocyclic or cage‐like architectures with an accessible internal cavity. Guest molecules can reside within…”
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Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair
Published in eLife (19-07-2021)“…Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in…”
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