Search Results - "Crowl, R."
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1
Induction of phospholipase A2 gene expression in human hepatoma cells by mediators of the acute phase response
Published in The Journal of biological chemistry (05-02-1991)“…Serum levels of phospholipase A2 (PLA2) activity have been shown to be elevated in cases of septic shock and rheumatoid arthritis. The cellular origin of serum…”
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2
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer
Published in Oncogene (26-02-2004)“…We report here that HtrA1, a candidate tumor suppressor, is downregulated in ovarian cancer. Expression of HtrA1 is downregulated in five of seven ovarian…”
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3
Constructing a Biomaterial to Simulate Extracellular Drug Transport in Solid Tumors
Published in Macromolecular bioscience (01-12-2020)“…Designing an in vitro model of the tumor extracellular microenvironment to screen intratumoral drugs is an active challenge. As recent clinical successes of…”
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4
Human HtrA, an Evolutionarily Conserved Serine Protease Identified as a Differentially Expressed Gene Product in Osteoarthritic Cartilage
Published in The Journal of biological chemistry (18-12-1998)“…The human homologue of the Escherichia coli htr A gene product was identified by the differential display analysis of transcripts expressed in osteoarthritic…”
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5
Structural determinants of the action against Escherichia coli of a human inflammatory fluid phospholipase A2 in concert with polymorphonuclear leukocytes
Published in The Journal of biological chemistry (21-10-1994)“…Extracellular 14-kDa phospholipases A2 (PLA2) in inflammatory exudates can contribute to bacterial phospholipid (PL) degradation during phagocytosis of…”
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6
Structure-function analysis of human interleukin-2. Identification of amino acid residues required for biological activity
Published in The Journal of biological chemistry (25-04-1987)“…To locate functional domains of the interleukin-2 (IL-2) protein, a cDNA clone encoding biologically active human IL-2 was mutagenized using synthetic…”
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7
Impact of genomics on inflammation research
Published in Inflammation research (01-05-1996)Get full text
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8
A comparison of mass balance, pharmacokinetics and disposition of [14C(U)]- and [125I]recombinant human interleukin-2 in cynomolgus monkeys
Published in Drug metabolism and disposition (01-09-1995)“…Recombinant human interleukin-2 (rHuIL-2) has been metabolically labeled with 14C amino acids in Escherichia coli and affinity purified on a rHuIL-2 receptor…”
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9
Proteolytic processing of avian sarcoma and leukosis viruses pol-endo recombinant proteins reveals another pol gene domain
Published in Journal of Virology (01-02-1987)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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10
Human group II phospholipase A2. Characterization of monoclonal antibodies and immunochemical quantitation of the protein in synovial fluid
Published in Journal of immunological methods (15-12-1991)“…Murine monoclonal and rabbit polyclonal antibodies were generated against human group II phospholipase A2 (PLA2) in order to study the role of this enzyme in…”
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11
Expression of Normal and Transforming H-ras Genes in Escherichia coli and Purification of their Encoded p21 Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1984)“…The H-ras gene of the BALB murine sarcoma virus (BALB-MSV) was placed under the transcriptional control of the tightly regulated PLpromoter of bacteriophage λ…”
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12
Determinants of the inhibitory action of purified 14-kDa phospholipases A2 on cell-free prothrombinase complex
Published in The Journal of biological chemistry (21-10-1994)“…It has been suggested (Kini, R. R., and Evans, H. J. (1987) J. Biol. Chem. 262, 14402-14407) that the anticoagulant activity of members of the 14-kDa…”
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13
Induction of the heat shock response of E. coli through stabilization of sigma 32 by the phage lambda cIII protein
Published in Genes & development (01-03-1987)“…The cIII protein of phage lambda favors the lysogenic response to infection by inhibiting the degradation of the lambda cII protein, which exerts the primary…”
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14
Molecular Cloning and Regulated Expression of the Human c-myc Gene in Escherichia coli and Saccharomyces cerevisiae: Comparison of the Protein Products
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1985)“…mRNA from human HL-60 cells was used to prepare a cDNA library, from which two full-length clones that encompass the complete c-myc coding region were…”
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15
Molecular weight of the functional unit of human leukocyte, fibroblast, and immune interferons
Published in The Journal of biological chemistry (25-08-1983)“…There is good agreement between the target molecular weight and the known molecular weight of human leukocyte interferons (about 20,000). The target molecular…”
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16
Renaturation of cobra venom phospholipase A2 expressed from a synthetic gene in Escherichia coli
Published in Biochimica et biophysica acta (09-01-1992)“…Cobra venom (Naja naja naja) phospholipase A2 (PLA2) contains 14 cysteines in the form of 7 disulfide bonds amongst its 119 amino acids. A gene encoding the…”
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17
Development of a High Volume Screen to Identify Inhibitors of Endothelial Cell Activation
Published in Analytical biochemistry (15-10-1996)“…We have developed a high throughput screen to identify inhibitors of endothelial cell activation using E-selectin cell-surface expression as a marker…”
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HTLV-III env gene products synthesized in E. coli are recognized by antibodies present in the sera of AIDS patients
Published in Cell (01-07-1985)“…The envelope gene of HTLV-III, the retrovirus directly linked to AIDS, encodes a protein of 856 amino acids. Our sequence analysis of the cloned HTLV-III…”
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Comparison of recombinant human immunodeficiency virus gag precursor and gag/env fusion proteins and a synthetic env peptide as diagnostic reagents
Published in Analytical biochemistry (01-03-1987)“…Diagnostic reagents for detection of human immunodeficiency virus (HIV) exposure with improved reliability may be provided by viral encoded proteins produced…”
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An immunological assay for chloramphenicol acetyltransferase
Published in Analytical biochemistry (01-05-1987)“…We report the production and utility of rabbit polyclonal antisera to the bacterial protein chloramphenicol acetyltransferase (CAT). The anti-CAT antibodies…”
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