Search Results - "Crowell, Kristen"

Impact of Alcohol on Glycemic Control and Insulin Action by Steiner, Jennifer L, Crowell, Kristen T, Lang, Charles H

“…Alcohol has profound effects on tissue and whole-body fuel metabolism which contribute to the increased morbidity and mortality in individuals with alcohol use…”
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Endoscopic Submucosal Dissection in the Management of an Adenoma Within the Area of Rectal Cancer After Complete Clinical Response by Tatar, Cihad, Crowell, Kristen T., Sapci, Ipek, Gorgun, I. Emre

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Contractility and Myofibrillar Content in Skeletal Muscle are Decreased During Post-Sepsis Recovery, But Not During the Acute Phase of Sepsis by Crowell, Kristen T., Lang, Charles H.

“…ABSTRACTConvalescence in humans after severe sepsis occurs over weeks to months and is associated with prolonged functional disabilities and impaired…”
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Perioperative use of NSAIDs and the risk of short-term endoscopic recurrence in Crohn's disease patients: A retrospective cohort study by Gaytan-Fuentes, Israel A., Ore, Ana Sofia, Vigna, Carolina, Cordova-Cassia, Carlos A., Crowell, Kristen T., Fabrizio, Anne C., Cataldo, Thomas E., Messaris, Evangelos

“…More evidence is needed on the use of NSAID based postoperative pain regimens for Crohn's disease (CD) and its association with recurrence. Our goal is to…”
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Alcohol Acutely Antagonizes Refeeding-Induced Alterations in the Rag GTPase-Ragulator Complex in Skeletal Muscle by Laufenberg, Lacee J, Crowell, Kristen T, Lang, Charles H

“…The Ragulator protein complex is critical for directing the Rag GTPase proteins and mTORC1 to the lysosome membrane mediating amino acid-stimulated protein…”
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Restorative Mechanisms Regulating Protein Balance in Skeletal Muscle During Recovery From Sepsis by Crowell, Kristen T, Soybel, David I, Lang, Charles H

“…ABSTRACTMuscle deconditioning is commonly observed in patients surviving sepsis. Little is known regarding the molecular mechanisms regulating muscle protein…”
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Safety and Efficacy of Inpatient Infliximab Rescue Therapy for Acute Crohn's Disease Flares by Whitlock, Ashlyn E, Arndt, Kevin R, Zakopoulos, Iordanis, Wong, Daniel J, Kaul, Sumedh, Feuerstein, Joseph, Crowell, Kristen T, Messaris, Evangelos

“…Describe the safety, complications, and need for urgent surgery in patients requiring inpatient rescue infliximab for acute Crohn's disease (CD) flare…”
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Models and Outcomes of Multidisciplinary Clinics in Colorectal Cancer by Lee, Seohyuk, Crowell, Kristen T, Zerillo, Jessica A

“…Multidisciplinary clinics (MDCs) represent a potential platform through which high-quality, patient-centered care grounded in interdisciplinary expertise may…”
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Early C-reactive protein after colorectal surgery is not predictive of anastomotic leak: a retrospective cohort study by Raje, Praachi, Allar, Benjamin G., Arndt, Kevin R., Crowell, Kristen T., Messaris, Evangelos

“…Purpose Prior studies suggest postoperative C-reactive protein (CRP) trends are sensitive for predicting anastomotic leak (AL) after elective colorectal…”
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Inability to replete white adipose tissue during recovery phase of sepsis is associated with increased autophagy, apoptosis, and proteasome activity by Crowell, Kristen T, Soybel, David I, Lang, Charles H

“…Adipose tissue is an important energy depot and endocrine organ, and the degree of adiposity impacts the host response to infection. However, little is known…”
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Interaction of Insurance and Neighborhood Income on Operative Colorectal Cancer Outcomes Within a National Database by Allar, Benjamin G., Abraham, Liza, Eruchalu, Chukwuma N., Rahimi, Amina, Dey, Tanujit, Peck, Gregory L., Kwakye, Gifty, Loehrer, Andrew P., Crowell, Kristen T., Messaris, Evangelos, Bergmark, Regan W., Ortega, Gezzer

“…Sociodemographic disparities in colorectal cancer (CRC) surgical patients are known. Few studies, however, have examined the intersection of insurance type and…”
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Disruption of REDD1 gene ameliorates sepsis-induced decrease in mTORC1 signaling but has divergent effects on proteolytic signaling in skeletal muscle by Steiner, Jennifer L, Crowell, Kristen T, Kimball, Scot R, Lang, Charles H

“…Sepsis-induced skeletal muscle atrophy and weakness are due in part to decreased mTORC1-mediated protein synthesis and increased proteolysis via the…”
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Dose-Intensified Infliximab Rescue Therapy for Severe Ulcerative Colitis Does Not Reduce Short-term Colectomy Rates or Increase Postoperative Complications by Kosaraju, Revanth S., Wong, Daniel J., Roth, Eve M., Cataldo, Thomas E., Fabrizio, Anne C., Crowell, Kristen T., Feuerstein, Joseph D., Messaris, Evangelos

“…Dose-intensified rescue therapy with infliximab for hospitalized patients with ulcerative colitis has become increasingly popular in recent years. However,…”
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Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue by Crowell, Kristen T., Steiner, Jennifer L., Coleman, Catherine S., Lang, Charles H.

“…Background Chronic alcohol consumption leads to a loss of white adipose tissue (WAT) but the underlying mechanisms for this lipodystrophy are not fully…”
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Mental health disorders as a risk factor in young patients with rectal prolapse by Whitlock, Ashlyn E., Arndt, Kevin R., Allar, Benjamin G., Fakler, Michelle N., Cataldo, Thomas E., Crowell, Kristen T., Fabrizio, Anne C., Messaris, Evangelos

“…Background Rectal prolapse (RP) typically presents in the elderly, though it can present in younger patients lacking traditional risk factors. The current…”
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Postoperative Outcomes in Ustekinumab-Treated Patients Undergoing Abdominal Operations for Crohn's Disease by Lightner, Amy L, McKenna, Nicholas P, Tse, Chung Sang, Hyman, Neil, Smith, Radhika, Ovsepyan, Gayane, Fleshner, Phillip, Crowell, Kristen, Koltun, Walter, Ferrante, Marc, D'Hoore, Andre, Lauwers, Nathalie, Verstockt, Bram, Spinelli, Antonino, DiCandido, Francesca, Raffals, Laura E, Mathis, Kellie L, Loftus, Jr, Edward V

“…Ustekinumab, a monoclonal antibody targeting interleukins-12 and -23 is used to treat adults with Crohn's disease (CD). We determined the 30-day postoperative…”
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Surveillance of Pancreatic Cancer Patients after Surgical Resection by Sheffield, Kristin M., Crowell, Kristen T., Lin, Yu-Li, Djukom, Clarisse, Goodwin, James S., Riall, Taylor S.

“…Background There are no clear recommendations to guide posttreatment surveillance in patients with pancreatic cancer. Our goal was to describe the…”
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Temporally Distinct Regulation of Pathways Contributing to Cardiac Proteostasis During the Acute and Recovery Phases of Sepsis by Crowell, Kristen T, Moreno, Samantha, Steiner, Jennifer L, Coleman, Catherine S, Soybel, David I, Lang, Charles H

“…BACKGROUND:Cardiac dysfunction is a common manifestation of sepsis and is associated with early increases in inflammation and decreases in myocardial protein…”
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Risk factors and implications of anastomotic complications after surgery for Crohn’s disease by Crowell, Kristen T, Messaris, Evangelos

“…Anastomotic complications occur more frequently in patients with Crohn’s disease leading to postoperative intra-abdominal septic complications(IASC). Patients…”
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Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction by Crowell, Kristen T., MD, Phillips, Brett E., PhD, Kelleher, Shannon L., PhD, Soybel, David I., MD, Lang, Charles H., PhD

“…Abstract Background Mild dietary zinc (Zn) deficiency is wide-spread in human populations, but its influence on recovery following acute illness is poorly…”
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