Search Results - "Crowe, Sean O"
-
1
Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
Published in Molecular cell (03-12-2020)“…The linkage, length, and architecture of ubiquitin (Ub) chains are all important variables in providing tight control over many biological paradigms. There are…”
Get full text
Journal Article -
2
Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo
Published in Analytical chemistry (Washington) (18-04-2017)“…Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles…”
Get full text
Journal Article -
3
Facile one-pot synthesis of tetrahydroisoquinolines from amino acids via hypochlorite-mediated decarboxylation and Pictet–Spengler condensation
Published in Tetrahedron letters (03-09-2014)“…A convenient method for oxidative decarboxylation of α-amino acids is presented. The aldehyde products may be isolated or converted to tetrahydroisoquinolines…”
Get full text
Journal Article -
4
-
5
Subunit-Specific Labeling of Ubiquitin Chains by Using Sortase: Insights into the Selectivity of Deubiquitinases
Published in Chembiochem : a European journal of chemical biology (17-08-2016)“…Information embedded in different ubiquitin chains is transduced by proteins with ubiquitin‐binding domains (UBDs) and erased by a set of hydrolytic enzymes…”
Get full text
Journal Article -
6
Towards Understanding the Role of Branched Ubiquitin Chains in Cellular Signaling
Published 01-01-2018“…The covalent attachment of the small protein, ubiquitin (Ub), to proteins represents one of the most versatile post-translational modifications in eukaryotic…”
Get full text
Dissertation