Search Results - "Crowe, Sean O"

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  1. 1

    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation by Deol, Kirandeep K., Crowe, Sean O., Du, Jiale, Bisbee, Heather A., Guenette, Robert G., Strieter, Eric R.

    Published in Molecular cell (03-12-2020)
    “…The linkage, length, and architecture of ubiquitin (Ub) chains are all important variables in providing tight control over many biological paradigms. There are…”
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    Journal Article
  2. 2

    Ubiquitin Chain Enrichment Middle-Down Mass Spectrometry Enables Characterization of Branched Ubiquitin Chains in Cellulo by Crowe, Sean O, Rana, Ambar S. J. B, Deol, Kirandeep K, Ge, Ying, Strieter, Eric R

    Published in Analytical chemistry (Washington) (18-04-2017)
    “…Ubiquitin (Ub) has a broad functional range that has been ascribed to the formation of an array of polymeric ubiquitin chains. Understanding the precise roles…”
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    Journal Article
  3. 3

    Facile one-pot synthesis of tetrahydroisoquinolines from amino acids via hypochlorite-mediated decarboxylation and Pictet–Spengler condensation by Maresh, Justin J., Crowe, Sean O., Ralko, Arthur A., Aparece, Mark D., Murphy, Casey M., Krzeszowiec, Mark, Mullowney, Michael W.

    Published in Tetrahedron letters (03-09-2014)
    “…A convenient method for oxidative decarboxylation of α-amino acids is presented. The aldehyde products may be isolated or converted to tetrahydroisoquinolines…”
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    Journal Article
  4. 4
  5. 5

    Subunit-Specific Labeling of Ubiquitin Chains by Using Sortase: Insights into the Selectivity of Deubiquitinases by Crowe, Sean O., Pham, Grace H., Ziegler, Jacob C., Deol, Kirandeep K., Guenette, Robert G., Ge, Ying, Strieter, Eric R.

    “…Information embedded in different ubiquitin chains is transduced by proteins with ubiquitin‐binding domains (UBDs) and erased by a set of hydrolytic enzymes…”
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    Journal Article
  6. 6

    Towards Understanding the Role of Branched Ubiquitin Chains in Cellular Signaling by Crowe, Sean O

    Published 01-01-2018
    “…The covalent attachment of the small protein, ubiquitin (Ub), to proteins represents one of the most versatile post-translational modifications in eukaryotic…”
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    Dissertation