Search Results - "Crowe, David A."
-
1
Dynamic representation of the temporal and sequential structure of rhythmic movements in the primate medial premotor cortex
Published in The Journal of neuroscience (03-09-2014)“…We determined the encoding properties of single cells and the decoding accuracy of cell populations in the medial premotor cortex (MPC) of Rhesus monkeys to…”
Get full text
Journal Article -
2
A prefrontal network model operating near steady and oscillatory states links spike desynchronization and synaptic deficits in schizophrenia
Published in eLife (06-02-2024)“…Schizophrenia results in part from a failure of prefrontal networks but we lack full understanding of how disruptions at a synaptic level cause failures at the…”
Get full text
Journal Article -
3
Monkey Prefrontal Neurons Reflect Logical Operations for Cognitive Control in a Variant of the AX Continuous Performance Task (AX-CPT)
Published in The Journal of neuroscience (06-04-2016)“…Cognitive control is the ability to modify the behavioral response to a stimulus based on internal representations of goals or rules. We sought to characterize…”
Get full text
Journal Article -
4
Neural Ensemble Decoding Reveals a Correlate of Viewer- to Object-Centered Spatial Transformation in Monkey Parietal Cortex
Published in The Journal of neuroscience (14-05-2008)“…The parietal cortex contains representations of space in multiple coordinate systems including retina-, head-, body-, and world-based systems. Previously, we…”
Get full text
Journal Article -
5
Understanding the parietal lobe syndrome from a neurophysiological and evolutionary perspective
Published in The European journal of neuroscience (01-06-2010)“…In human and nonhuman primates parietal cortex is formed by a multiplicity of areas. For those of the superior parietal lobule (SPL) there exists a certain…”
Get full text
Journal Article -
6
Parallel Processing of Serial Movements in Prefrontal Cortex
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2002)“…A key idea in Lashley's formulation of the problem of serial order in behavior is the postulated neural representation of all serial elements before the action…”
Get full text
Journal Article -
7
University-Wide Digital Skills Training: A Case Study Evaluation
Published in Education sciences (01-04-2023)“…Digital competencies and confidence are thought to be critical to success in higher education. However, despite learning frequently taking place online through…”
Get full text
Journal Article -
8
Cognitive modulation of local and callosal neural interactions in decision making
Published in Frontiers in neuroscience (11-08-2014)“…Traditionally, the neurophysiological mechanisms of cognitive processing have been investigated at the single cell level. Here we show that the dynamic,…”
Get full text
Journal Article -
9
Differential brain activity states during the perception and nonperception of illusory motion as revealed by magnetoencephalography
Published in Proceedings of the National Academy of Sciences - PNAS (28-12-2010)“…We studied visual perception using an annular random-dot motion stimulus called the racetrack. We recorded neural activity using magnetoencephalography while…”
Get full text
Journal Article -
10
Differential Roles of Mediodorsal Nucleus of the Thalamus and Prefrontal Cortex in Decision-Making and State Representation in a Cognitive Control Task Measuring Deficits in Schizophrenia
Published in The Journal of neuroscience (19-02-2020)“…The mediodorsal nucleus of the thalamus (MD) is reciprocally connected with the prefrontal cortex (PFC), and although the MD has been implicated in a range of…”
Get full text
Journal Article -
11
Blocking NMDAR Disrupts Spike Timing and Decouples Monkey Prefrontal Circuits: Implications for Activity-Dependent Disconnection in Schizophrenia
Published in Neuron (Cambridge, Mass.) (27-06-2018)“…We employed multi-electrode array recording to evaluate the influence of NMDA receptors (NMDAR) on spike-timing dynamics in prefrontal networks of monkeys as…”
Get full text
Journal Article -
12
Rapid sequences of population activity patterns dynamically encode task-critical spatial information in parietal cortex
Published in The Journal of neuroscience (01-09-2010)“…We characterized the temporal dynamics of population activity in parietal cortex of monkeys as they solved a spatial cognitive problem posed by an object…”
Get full text
Journal Article -
13
Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition
Published in Nature neuroscience (01-10-2013)“…To examine the nature of information encoded by prefrontal output signals, the authors simultaneously recorded neuronal activity in monkey prefrontal and…”
Get full text
Journal Article -
14
Implicit and Explicit Learning Mechanisms Meet in Monkey Prefrontal Cortex
Published in Neuron (Cambridge, Mass.) (11-10-2017)“…In this issue, Loonis et al. (2017) provide the first description of unique synchrony patterns differentiating implicit and explicit forms of learning in…”
Get full text
Journal Article -
15
Shared Neural Activity But Distinct Neural Dynamics for Cognitive Control in Monkey Prefrontal and Parietal Cortex
Published in The Journal of neuroscience (12-04-2023)“…To better understand how prefrontal networks mediate forms of cognitive control disrupted in schizophrenia, we translated a variant of the AX continuous…”
Get full text
Journal Article -
16
Disparate insults relevant to schizophrenia converge on impaired spike synchrony and weaker synaptic interactions in prefrontal local circuits
Published in Current biology (10-01-2022)“…Schizophrenia results from hundreds of known causes, including genetic, environmental, and developmental insults that cooperatively increase risk of developing…”
Get full text
Journal Article -
17
Representing Spatial Relationships in Posterior Parietal Cortex: Single Neurons Code Object-Referenced Position
Published in Cerebral cortex (New York, N.Y. 1991) (01-12-2007)“…The brain computes spatial relationships as necessary to achieve behavioral goals. Loss of this spatial cognitive ability after damage to posterior parietal…”
Get full text
Journal Article -
18
Cognitive Control Errors in Nonhuman Primates Resembling Those in Schizophrenia Reflect Opposing Effects of NMDA Receptor Blockade on Causal Interactions Between Cells and Circuits in Prefrontal and Parietal Cortices
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-07-2020)“…The causal biology underlying schizophrenia is not well understood, but it is likely to involve a malfunction in how neurons adjust synaptic connections in…”
Get full text
Journal Article -
19
Thinking in spatial terms: decoupling spatial representation from sensorimotor control in monkey posterior parietal areas 7a and LIP
Published in Frontiers in integrative neuroscience (01-01-2013)“…Perhaps the simplest and most complete description of the cerebral cortex is that it is a sensorimotor controller whose primary purpose is to represent stimuli…”
Get full text
Journal Article -
20
magnetoencephalography study of choice bias
Published in Experimental brain research (01-04-2010)“…Many factors can influence, or bias, human decision making. A considerable amount of research has investigated the neural correlates of such biases, mostly…”
Get full text
Journal Article