Search Results - "Crow, Michael T"

Bax regulates primary necrosis through mitochondrial dynamics by Whelan, Russell S, Konstantinidis, Klitos, Wei, An-Chi, Chen, Yun, Reyna, Denis E, Jha, Saurabh, Yang, Ying, Calvert, John W, Lindsten, Tullia, Thompson, Craig B, Crow, Michael T, Gavathiotis, Evripidis, Dorn, Gerald W. II, O'Rourke, Brian, Kitsis, Richard N

“…The defining event in apoptosis is mitochondrial outer membrane permeabilization (MOMP), allowing apoptogen release. In contrast, the triggering event in…”
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Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice by Liu, Manchang, Grigoryev, Dmitry N., Crow, Michael T., Haas, Mark, Yamamoto, Masayuki, Reddy, Sekhar P., Rabb, Hamid

“…Oxidative stress is involved in acute kidney injury due to ischemia–reperfusion and chemotherapy-induced nephrotoxicity. To investigate their basic mechanisms…”
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The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis by Crow, Michael T, Mani, Kartik, Nam, Young-Jae, Kitsis, Richard N

“…Apoptosis has been causally linked to the pathogenesis of myocardial infarction and heart failure in rodent models. This death process is mediated by two…”
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Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes by Zhang, Manling, Koitabashi, Norimichi, Nagayama, Takahiro, Rambaran, Ryan, Feng, Ning, Takimoto, Eiki, Koenke, Trisha, O'Rourke, Brian, Champion, Hunter C., Crow, Michael T., Kass, David A.

“…Cyclic GMP-selective phosphodiesterase type 5 (PDE5) has been traditionally thought to play a little role in cardiac myocytes, yet recent studies using…”
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Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension by Angelini, Daniel J, Su, Qingning, Yamaji-Kegan, Kazuyo, Fan, Chunling, Skinner, John T, Champion, Hunter C, Crow, Michael T, Johns, Roger A

“…Pulmonary hypertension (PH) is a serious disease of multiple etiologies mediated by hypoxia, immune stimuli, and elevated pulmonary pressure that leads to…”
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Apoptosis Repressor with Caspase Recruitment Domain Protects against Cell Death by Interfering with Bax Activation by Gustafsson, Asa B, Tsai, Joseph G, Logue, Susan E, Crow, Michael T, Gottlieb, Roberta A

“…Myocardial ischemia/reperfusion (I/R) is associated with an extensive loss of myocardial cells. The apoptosis repressor with caspase recruitment domain (ARC)…”
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Genetic and Pharmacologic Evidence Links Oxidative Stress to Ventilator-induced Lung Injury in Mice by Papaiahgari, Srinivas, Yerrapureddy, Adi, Reddy, Swetha R, Reddy, Narsa M, Dodd-O, Jeffery M, Crow, Michael T, Grigoryev, Dimitry N, Barnes, Kathleen, Tuder, Rubin M, Yamamoto, Masayuki, Kensler, Thomas W, Biswal, Shyam, Mitzner, Wayne, Hassoun, Paul M, Reddy, Sekhar P

“…Mechanical ventilation (MV) is an indispensable therapy for critically ill patients with acute lung injury and the adult respiratory distress syndrome…”
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Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase by D'Alessio, Franco R, Tsushima, Kenji, Aggarwal, Neil R, Mock, Jason R, Eto, Yoshiki, Garibaldi, Brian T, Files, Daniel C, Avalos, Claudia R, Rodriguez, Jackie V, Waickman, Adam T, Reddy, Sekhar P, Pearse, David B, Sidhaye, Venkataramana K, Hassoun, Paul M, Crow, Michael T, King, Landon S

“…Although early events in the pathogenesis of acute lung injury (ALI) have been defined, little is known about the mechanisms mediating resolution. To search…”
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Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-κB Transcriptional Activation and Cytokine Secretion by YEH, Chen-Hsiung, STURGIS, Lydia, HAIDACHER, Joe, ZHANG, Xue-Nong, SHERWOOD, Sidney J, BJERCKE, Robert J, JUHASZ, Ondrej, CROW, Michael T, TILTON, Ronald G, DENNER, Larry

“…Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-κB Transcriptional Activation and Cytokine Secretion…”
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Pulmonary Epithelial Neuropilin-1 Deletion Enhances Development of Cigarette Smoke-induced Emphysema by Le, Anne, Zielinski, Rachel, He, Chaoxia, Crow, Michael T, Biswal, Shyam, Tuder, Rubin M, Becker, Patrice M

“…Cigarette smoke (CS) exposure is an important risk factor for chronic obstructive pulmonary disease; however, not all smokers develop disease, suggesting that…”
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The Pro-angiogenic Cytokine Pleiotrophin Potentiates Cardiomyocyte Apoptosis through Inhibition of Endogenous AKT/PKB Activity by Li, Jinliang, Wei, Hong, Chesley, Alan, Moon, Chanil, Krawczyk, Melissa, Volkova, Maria, Ziman, Bruce, Margulies, Kenneth B., Talan, Mark, Crow, Michael T., Boheler, Kenneth R.

“…Pleiotrophin is a development-regulated cytokine and growth factor that can promote angiogenesis, cell proliferation, or differentiation, and it has been…”
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Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo by Szczepaniak, William S, Zhang, Yingze, Hagerty, Sarah, Crow, Michael T, Kesari, Priya, Garcia, Joe G.N, Choi, Augustine M.K, Simon, Brett A, McVerry, Bryan J

“…S1P has been demonstrated to protect against the formation of lipopolysaccharide (LPS)-induced lung edema when administered concomitantly with LPS. In the…”
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Role of CaM kinase II and ERK activation in thrombin-induced endothelial cell barrier dysfunction by Borbiev, Talaibek, Verin, Alexander D, Birukova, Anna, Liu, Feng, Crow, Michael T, Garcia, Joe G N

“…We have previously shown that thrombin-induced endothelial cell barrier dysfunction involves cytoskeletal rearrangement and contraction, and we have elucidated…”
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Hypoxia, BNip3 Proteins, and the Mitochondrial Death Pathway in Cardiomyocytes by Crow, Michael T

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Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury by Gandolfo, Maria Teresa, Jang, Hye Ryoun, Bagnasco, Serena M., Ko, Gang-Jee, Agreda, Patricia, Satpute, Shailesh R., Crow, Michael T., King, Landon S., Rabb, Hamid

“…T lymphocytes modulate early ischemia-reperfusion injury in the kidney; however, their role during repair is unknown. We studied the role of…”
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Interaction of Filamin A with the Insulin Receptor Alters Insulin-dependent Activation of the Mitogen-activated Protein Kinase Pathway by He, Hua-Jun, Kole, Sutapa, Kwon, Yong-Kook, Crow, Michael T., Bernier, Michel

“…The biological actions of insulin are associated with a rapid reorganization of the actin cytoskeleton within cells in culture. Even though this event requires…”
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Shear Stress-Mediated Cytoskeletal Remodeling and Cortactin Translocation in Pulmonary Endothelial Cells by Birukov, Konstantin G, Birukova, Anna A, Dudek, Steven M, Verin, Alexander D, Crow, Michael T, Zhan, Xi, DePaola, Natacha, Garcia, Joe G. N

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Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation by Templin, Andrew T, Samarasekera, Tanya, Meier, Daniel T, Hogan, Meghan F, Mellati, Mahnaz, Crow, Michael T, Kitsis, Richard N, Zraika, Sakeneh, Hull, Rebecca L, Kahn, Steven E

“…Islet amyloid is present in more than 90% of individuals with type 2 diabetes, where it contributes to β-cell apoptosis and insufficient insulin secretion…”
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Activation of CaMKIIδC Is a Common Intermediate of Diverse Death Stimuli-induced Heart Muscle Cell Apoptosis by Zhu, Weizhong, Woo, Anthony Yiu-Ho, Yang, Dongmei, Cheng, Heping, Crow, Michael T., Xiao, Rui-Ping

“…Ca2+-calmodulin-dependent protein kinase II (CaMKII) is expressed in many mammalian cells, with the δ isoform predominantly expressed in cardiomyocytes…”
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Adenovirus-mediated gene transfer of the human tissue inhibitor of metalloproteinase-2 blocks vascular smooth muscle cell invasiveness in vitro and modulates neointimal development in vivo by CHENG, L, MANTILE, G, CAPOGROSSI, M. C, PAULY, R, NATER, C, FELICI, A, MONTICONE, R, BILATO, C, GLUZBAND, Y. A, CROW, M. T, STETLER-STEVENSON, W

“…Endovascular injury induced by balloon withdrawal leads to the increased activation of matrix metalloproteinases (MMPs) in the vascular wall, allowing smooth…”
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