Search Results - "Crouzier, Thomas"

Mucins as multifunctional building blocks of biomaterials by Petrou, Georgia, Crouzier, Thomas

“…Mucins are large glycoproteins that are ubiquitous in the animal kingdom. Mucins coat the surfaces of many cell types and can be secreted to form mucus gels…”
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Polyelectrolyte Multilayer Films of Controlled Stiffness Modulate Myoblast Cell Differentiation by Ren, Kefeng, Crouzier, Thomas, Roy, Christian, Picart, Catherine

“…In addition to their chemical properties and topographical features, the mechanical properties of gels have been recently demonstrated to play an important…”
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Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications by Boudou, Thomas, Crouzier, Thomas, Ren, Kefeng, Blin, Guillaume, Picart, Catherine

“…The design of advanced functional materials with nanometer‐ and micrometer‐scale control over their properties is of considerable interest for both fundamental…”
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Layer‐By‐Layer Films as a Biomimetic Reservoir for rhBMP‐2 Delivery: Controlled Differentiation of Myoblasts to Osteoblasts by Crouzier, Thomas, Ren, Kefeng, Nicolas, Claire, Roy, Christian, Picart, Catherine

“…Efficient delivery of growth or survival factors to cells is one of the most important long‐term challenges of current cell‐based tissue engineering…”
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Charged glycan residues critically contribute to the adsorption and lubricity of mucins by Marczynski, Matthias, Balzer, Bizan N., Jiang, Kun, Lutz, Theresa M., Crouzier, Thomas, Lieleg, Oliver

“…[Display omitted] •Removal of negatively charged glycan moieties compromises mucin lubricity•Glycan removal affects mucin adsorption efficiency but not mucin…”
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Swimming bacteria promote dispersal of non-motile staphylococcal species by Samad, Tahoura, Billings, Nicole, Birjiniuk, Alona, Crouzier, Thomas, Doyle, Patrick S, Ribbeck, Katharina

“…Swimming motility is considered a beneficial trait among bacterial species as it enables movement across fluid environments and augments invasion of tissues…”
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Presentation of BMP-2 from a Soft Biopolymeric Film Unveils its Activity on Cell Adhesion and Migration by Crouzier, Thomas, Fourel, Laure, Boudou, Thomas, Albigès-Rizo, Corinne, Picart, Catherine

“…The dramatic effect of morphogenetic protein 2 (BMP‐2), presented to cells in a “matrix bound” manner is described. BMP‐2 is either delivered in solution or…”
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Mucin Multilayers Assembled through Sugar–Lectin Interactions by Crouzier, Thomas, Beckwitt, Colin H, Ribbeck, Katharina

“…Multilayer films of biopolymers are attractive tools to exploit the extraordinary properties of certain biomacromolecules and introduce new functionalities to…”
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Modulating Mucin Hydration and Lubrication by Deglycosylation and Polyethylene Glycol Binding by Crouzier, Thomas, Boettcher, Kathrin, Geonnotti, Anthony R., Kavanaugh, Nicole L., Hirsch, Julie B., Ribbeck, Katharina, Lieleg, Oliver

“…A key property of mucin glycoproteins is their exceptional capacity to hydrate and lubricate surfaces. In vivo, mucins assemble into mucus hydrogels that cover…”
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Antifungal Activity of Chitosan against Histoplasma capsulatum in Planktonic and Biofilm Forms: A Therapeutic Strategy in the Future? by Brilhante, Raimunda Sâmia Nogueira, Costa, Anderson da Cunha, Mesquita, Jacó Ricarte Lima de, Dos Santos Araújo, Gessica, Freire, Rosemeyre Souza, Nunes, João Victor Serra, Nobre, Augusto Feynman Dias, Fernandes, Mirele Rodrigues, Rocha, Marcos Fábio Gadelha, Pereira Neto, Waldemiro de Aquino, Crouzier, Thomas, Schimpf, Ulrike, Viera, Rodrigo Silveira

“…Histoplasmosis is a respiratory disease caused by , a dimorphic fungus, with high mortality and morbidity rates, especially in immunocompromised patients…”
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Modification of Single Walled Carbon Nanotube Surface Chemistry to Improve Aqueous Solubility and Enhance Cellular Interactions by Crouzier, Thomas, Nimmagadda, Aditya, Nollert, Matthias U, McFetridge, Peter S

“…Single walled carbon nanotubes (SWNTs) continue to demonstrate the potential of nanoscaled materials in a wide range of applications. The ability to modulate…”
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Portable Quartz Crystal Resonator Sensor for Characterising the Gelation Kinetics and Viscoelastic Properties of Hydrogels by Miranda-Martínez, Andrés, Yan, Hongji, Silveira, Valentin, Serrano-Olmedo, José Javier, Crouzier, Thomas

“…Hydrogel biomaterials have found use in various biomedical applications partly due to their biocompatibility and tuneable viscoelastic properties. The ideal…”
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A defensive blanket against viral infection of the lungs by Crouzier, Thomas

“…A safe, inhalable formulation of mucin-interacting hydrogel microparticles creates a dense protective network in the lungs against viral infections…”
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Researchers in the cloud by Crouzier, Thomas

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Polysaccharide-based polyelectrolyte multilayers by Crouzier, Thomas, Boudou, Thomas, Picart, Catherine

“…In recent years, the layer-by-layer technique has grown in various fields. One of the emerging trends of bio-applications is the use of polysaccharides as main…”
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Structural Alterations of Mucins Are Associated with Losses in Functionality by Marczynski, Matthias, Jiang, Kun, Blakeley, Matthew, Srivastava, Vaibhav, Vilaplana, Francisco, Crouzier, Thomas, Lieleg, Oliver

“…Commercial mucin glycoproteins are routinely used as a model to investigate the broad range of important functions mucins fulfill in our bodies, including…”
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Immune‐Informed Mucin Hydrogels Evade Fibrotic Foreign Body Response In Vivo by Yan, Hongji, Seignez, Cédric, Hjorth, Morgan, Winkeljann, Benjamin, Blakeley, Matthew, Lieleg, Oliver, Phillipson, Mia, Crouzier, Thomas

“…The immune‐mediated foreign body response to biomaterial implants can trigger the formation of insulating fibrotic capsules that can compromise implant…”
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Ion Pairing and Hydration in Polyelectrolyte Multilayer Films Containing Polysaccharides by Crouzier, Thomas, Picart, Catherine

“…Thin films constituted of poly(l-lysine) (PLL) as polycation and of the anionic polysaccharides hyaluronan (HA), chondroitin sulfate (CSA), and heparin (HEP)…”
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Covalently-crosslinked mucin biopolymer hydrogels for sustained drug delivery by Duffy, Connor V., David, Laurent, Crouzier, Thomas

“…[Display omitted] The sustained delivery of both hydrophobic and hydrophilic drugs from hydrogels has remained a challenge requiring the design and scalable…”
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Spatial Configuration and Composition of Charge Modulates Transport into a Mucin Hydrogel Barrier by Li, Leon D., Crouzier, Thomas, Sarkar, Aniruddh, Dunphy, Laura, Han, Jongyoon, Ribbeck, Katharina

“…The mucus barrier is selectively permeable to a wide variety of molecules, proteins, and cells, and establishes gradients of these particulates to influence…”
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